Epithelial Pathology

Angela, C.

doi:10.1016/b978-1-4160-3435-3.50012-9

Cited by 5 publications

(6 citation statements)

References 456 publications

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“…Meanwhile, chronic trauma due to various factors, such as a fractured tooth, sharp edged teeth, root pieces or improper denture, is the most typical reason for carcinoma of the lateral border and ventral surface of the tongue. 3,10 In the present article, in case 3, it is difficult to guess the probable etiology for OSCC of the lateral border of the tongue because, even though the patient has teeth with sharp cusps, he had a history of an adverse habit for 15 years.…”

Section: Discussionmentioning

confidence: 99%

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Clinical aspects of oral cancer: A case report series

Dangore–Khasbage¹

2017

Dent. Med. Probl.

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Section: Discussionmentioning

confidence: 99%

“…10 The common symptoms of OSCC are a painless growth, painless ulcer, loosening of teeth, exfoliation of teeth, discomfort, difficulty in swallowing, etc.…”

Section: Discussionmentioning

confidence: 99%

Clinical aspects of oral cancer: A case report series

Dangore–Khasbage¹

2017

Dent. Med. Probl.

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Section: Introductionmentioning

confidence: 99%

“…[1] Histopathologically it is graded into well, moderate and poorly differentiated lesion, based on the keratinization and degree of anaplasia. [1] Other recognized variants of oral SCC include verrucous, spindle, adenosquamous and basaloid variants. [1] This case report describes a case of oral SCC involving the left posterior lateral border of the tongue and lingual vestibule in a 35 year old, which showed prominent clear cell changes.…”

Section: Introductionmentioning

confidence: 99%

“…[1] Other recognized variants of oral SCC include verrucous, spindle, adenosquamous and basaloid variants. [1] This case report describes a case of oral SCC involving the left posterior lateral border of the tongue and lingual vestibule in a 35 year old, which showed prominent clear cell changes. Previously, seven such cases are reported involving the skin[23] and one case in the oral cavity,[4] indicating the rarity of this oral variant.…”

Section: Introductionmentioning

confidence: 99%

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A rare case of clear cell variant of oral squamous cell carcinoma

et al. 2015

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Oral squamous cell carcinoma with prominent clear cell differentiation is a rare occurrence. A 35-year-old female patient presented with a nonhealing ulcer persistent for 1-month involving the left lateral border of the tongue and lingual vestibule. Lobules of malignant squamous epithelial cells with abundant cytoplasm and vesicular nuclei in the connective tissue were observed following histopathology. Neoplastic cells constituting majority of lobules exhibited clear cell changes. Periodic acid-Schiff and mucicarmine stains showed negative reaction. Immunohistochemical study using antibody for cytokeratin, revealed diffuse and intense positivity. The neoplastic cells showed complete negative reaction with antibodies for vimentin, smooth muscle actin and homatropine bromide-45 antigens.

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Papillary Variant of Squamous Cell Carcinoma Arising on the Gingiva: 61 Cases Reported from Within a Larger Series of Gingival Squamous Cell Carcinoma

Fitzpatrick

Neuman

Cohen

et al. 2013

Head and Neck Pathol

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Papillary squamous cell carcinoma (PSCCA) is a rarely occurring variant of squamous cell carcinoma (SCCA) with distinctive exophytic and papillary features and a more favorable prognosis than conventional SCCA. The larynx is the most commonly affected site in the head and neck. The oral cavity, oropharynx, sinonasal tract, and nasopharynx are also affected. Within the oral cavity cases have been reported on the alveolar ridge, oral mucosa, floor of the mouth, ventral tongue, and rarely other areas. We identified 61 cases of gingival PSCCA within the parameters of a larger study of 519 cases of gingival SCCA. We evaluated the clinical and histologic features of these lesions. The average age of the PSCCA patient was 74 years, with a very slight male predominance of 1.2:1. The mandible was affected nearly twice as often (64 %, n = 39) as the maxilla (35 %, n = 21, and 1 % of cases unspecified), and the most common location by far was the mandibular posterior region (52 %, n = 32). Most lesions were reportedly present over 2 months in duration (48 %, n = 29) prior to biopsy but a significant amount of clinicians were unsure of the duration of the lesion as well (36 %, n = 22). Only 10 cases (16 %) were reportedly present less than 2 months. The most common clinical presentation was that of an erythematous or mixed white and red exophytic mass (74 %, n = 45). 62 % (n = 38) of submitting clinicians considered a malignant or premalignant lesion in their differential diagnosis, but other clinical impressions included papillomas, reactive gingival lesions, and fungal infections. Histologically, 88 % (n = 52 of 59 cases graded) of the lesions were either well or moderately-well differentiated. PSCCA is a rare subtype of SCCA which has been reported infrequently involving the gingiva or alveolar ridges but should be considered by clinicians for the differential diagnosis of papillary gingival masses.

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Epithelial Pathology

Cited by 5 publications

References 456 publications

Clinical aspects of oral cancer: A case report series

Clinical aspects of oral cancer: A case report series

A rare case of clear cell variant of oral squamous cell carcinoma

Papillary Variant of Squamous Cell Carcinoma Arising on the Gingiva: 61 Cases Reported from Within a Larger Series of Gingival Squamous Cell Carcinoma

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