Epithelioid leiomyosarcoma of the larynx

Sindwani, Raj; Matthews, T. Wayne; Thomas, Justin; Venkatesan, Varagur

doi:10.1002/(sici)1097-0347(199809)20:6<563::aid-hed12>3.0.co;2-l

Cited by 10 publications

(10 citation statements)

References 15 publications

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“…LLMS is uncommon; we identified 62 cases in the English‐language literature (Table 1). 1,3–55 Tangjaturonrasme found that the number of LLMS cases was increasing; four cases were reported from 1961 to 1970, compared to 21 cases from 2000 to 2010. This may be a result of advances in diagnostic techniques, including immunohistochemical techniques and electron microscopy 46 .…”

Section: Discussion/literature Reviewmentioning

confidence: 99%

“…It was first reported by Jackson and Jackson in 1939 2 . To the best of our knowledge, 62 cases of LLMS have been reported in the English‐language literature 1,3–55 …”

Section: Introductionmentioning

confidence: 99%

“…Factors predisposing to LLMS include radiation exposure, surgery, multiple basal cell carcinoma syndrome, Gardner syndrome, tuberous sclerosis, neurofibromatosis, Werner syndrome, retinoblastoma, Turcot syndrome, and Epstein–Barr virus (EBV) infection in immunosuppressed patients 1,3–55 …”

Section: Introductionmentioning

confidence: 99%

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Epstein–Barrvirus‐associated leiomyosarcoma of the larynx in an adult patient with human immunodeficiency virus infection: Case report and review of the literature

et al. 2022

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We investigated the clinical features, treatment, and prognosis of laryngeal leiomyosarcoma (LLMS) and Epstein-Barr virus-associated (EBV-associated) LMS. We report a case of EBV-associated LLMS in an adult patient with HIV infection. We also conducted a review of the English-language literature on LLMS and EBV-associated leiomyosarcoma. To the best of our knowledge, 62 cases of LLMS and EBV-associated leiomyosarcoma have been reported to date. Of patients with LLS, 18.9% had distant metastases and 17.0% had local recurrence. The overall 5-year survival rate was 64.0%. Distant metastases affected the survival of patients with LLMS (p = 0.04). EBV-positive patients had a low survival rate (p = 0.01). Among patients with EBV-associated LMS, 8.2% had distant metastases and recurrence and the overall 5-year survival rate was 50.0%. EBV-associated LLMS is rare. The EBV infection might be a poor prognostic factor of LLMS.

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Section: Discussion/literature Reviewmentioning

confidence: 99%

“…It was first reported by Jackson and Jackson in 1939 2 . To the best of our knowledge, 62 cases of LLMS have been reported in the English‐language literature 1,3–55 …”

Section: Introductionmentioning

confidence: 99%

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Epstein–Barrvirus‐associated leiomyosarcoma of the larynx in an adult patient with human immunodeficiency virus infection: Case report and review of the literature

et al. 2022

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“…[1][2][3][4] All reported cases are primary leiomyosarcoma. 2 Additionally, the benign counterpart, leiomyoma, is rarely reported.…”

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confidence: 99%

“…2 Additionally, the benign counterpart, leiomyoma, is rarely reported. 4 The reason for the paucity could be the low amount of smooth muscles in this region. The development of leiomyosarcoma after previously treated SCC is an unreported event at this anatomic site.…”

mentioning

confidence: 99%