EPOCHA-AH 1998–2017. Dynamics of prevalence, awareness of arterial hypertension, treatment coverage, and effective control of blood pressure in the European part of the Russian Federation

Abstract

Aim.To perform a repeated epidemiological study of a representative sample in the European part of the Russian Federation in 2017 and to compare the dynamics of arterial hypertension (AH) prevalence with the effectiveness of blood pressure (BP) control in the population compared to 1998, 2002, and 2007.Materials and methods.A representative sample of the European part of the Russian Federation was created in 2002 and re-examined in 2007 and 2017. In 1998, a pilot project was performed for examining a representative sample for the Nizhniy Novgorod region.Results.During 19 years of follow-up, the AH prevalence increased from 35.5 to 43.3%. Te awareness and treatment coverage reached 76.9 and 79.3%, respectively, in 2017. Achievement of the target BP with a single measurement also increased among patients receiving antihypertensive medication from 14.3 to 34.9%. For the treatment of AH, medium-acting antihypertensive drugs are used, ofen at suboptimal doses.Conclusion.Epidemiological indices of awareness, treatment coverage, and number of effectively managed patients with AH have improved. However, the AH prevalence has increased by 7.8% for 19 years, which indicates inefciency of the primary prevention of this disease.

Prevalence, Awareness, Treatment and Control of Hypertension in Russian Federation (Data of Observational ESSERF-2 Study)

“…Увеличение частоты АГ в ЭССЕ-2 продемонстрировано в Рязанской области в сравнении с проводимым ранее на этой территории исследованием МЕРИДИАН-РО, в котором распространенность АГ составила 45,9% [10]. О росте этого показателя говорят и исследователи проекта ЭПОХА-АГ, проводимого на Европейской части РФ, однако эти данные трудно использовать для сравнения, так как исследование по описанному авторами дизайну является когортным [13].…”

“…In the first decade of the 2000s, within the framework of the Federal Target Program for the Prevention and Treatment of AH in the Russian Federation (AH Monitoring), several representative sections were made, in which the prevalence of AH in the country was studied [12]. From 2002 to 2017 the cohort observation EPOCHA-AH was conducted in 8 regions of the European part of the Russian Federation [13].…”

“…С 2002 по 2017 гг. в 8 регионах европейской части РФ было проведено когортное наблюдение ЭПОХА-АГ [13].…”

“…The growth of this parameter is also indicated by researchers of the EPOCHA-AH project conducted in the European part of the Russian Federation. However, these data are difficult to use for comparison, since the study as described by the authors has the cohort design [13].…”

Comparative Analysis of Lipid Peroxidation System in Humans and Rats with Arterial Hypertension

“…Arterial hypertension (AH) is one of the most common diseases of the cardiovascular system, characterized by a persistent increase in blood pressure. (1,2) AH often manifests itself in childhood and adolescence. (3,4) Like any pathological condition, AH, in addition to pathological reactions, is accompanied by the inclusion of sanogenetic mechanisms reflecting the dynamic complex of defense and adaptive reactions arising under the influence of a pathogenic factor and aimed at restoring the disturbed selfregulation of the body.…”