Epstein-Barr virus-associated gastric carcinoma: Evidence of age-dependence among a Mexican population

Abstract

Among Latin-American countries, Mexico has the lowest frequency of EBVaGC. Indeed, the Mexican population >50 years of age was selectively affected. Ethnic variations are responsible for the epidemiologic behavior of EBVaGC among the worldwide population.

Association Of Epstein-Barr Virus With Gastric Carcinoma Among Sudanese Patients

“…Consistent to the previous studies males showed higher risk of infection compared to females [20,21], metaanalysis of 15,952 cases shown that EBV-positive in GC occur more frequently in male than in female patients [22]. Most studies indicated that lifestyle or occupational factors may exist among males [10,23,24].The highest incidence of EBV in Gastric cancer was at (50-59) year age [21,25].…”

“…Most studies indicated that lifestyle or occupational factors may exist among males [10,23,24].The highest incidence of EBV in Gastric cancer was at (50-59) year age [21,25]. Occurrence in elderly persons and male predominance are common in EBV-associated gastric carcinomas [26].…”

The presence of JC virus in gastric carcinomas correlates with patient's age, intestinal histological type and aberrant methylation of tumor suppressor genes

“…Similar finding has been reported for Epstein-Barr virusassociated gastric carcinomas. 37 Furthermore, in this study, we found that JCV is more commonly detected in intestinal histological type of gastric carcinomas (P ¼ 0.04). This finding seems in harmony with the known description in literature.…”

Epstein–Barr virus antibody level and gastric cancer risk in Korea: a nested case–control study

“…In our study, EBV latent infection antibodies were not associated with gastric cancer risk. These differences may be due to infection by different EBV strains, which are believed to influence EBV-infected gastric cancer worldwide in combination with different environmental factors (Herrera-Goepfert et al, 2005).…”

“…Epstein -Barr virus infection is believed to be related to 5 -16% of gastric adenocarcinomas, with variations across populations (Burgess et al, 2002;Macsween and Crawford, 2003;Correa et al, 2004;Herrera-Goepfert et al, 2005). Most studies to date have been tumour tissue-based, providing information about the role of EBV in gastric carcinogenesis, but providing limited information on the association between EBV infection and gastric cancer, particularly adenocarcinoma -the most prominent histology (Tokunaga and Land, 1998;Chang and Kim, 2005;Akiba et al, 2008).…”