Equally weighted multivariate optimization of feeding rate for sub‐yearling great sturgeon (<scp><i>Huso huso</i></scp>) using desirability function model

Mani, Amir; Ebrahimi, Eisa

doi:10.1111/jwas.12857

Cited by 6 publications

(5 citation statements)

References 45 publications

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“…Desirability function is a tool to determine the optimum measure for independent variables by first, evaluating the desirability index for each response, and then merging all response variables into a single desirability function ranging from 0 to 1 to describe the superior values of the independent parameters. ( Mani and Ebrahimi, 2022 ; Naguib et al, 2020 ).…”

Section: Methodsmentioning

confidence: 99%

Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity & in vivo biodistribution utilizing radioiodinated zopiclone

Taha

Nour

Mamdouh

et al. 2023

International Journal of Pharmaceutics: X

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Section: Methodsmentioning

confidence: 99%

Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity & in vivo biodistribution utilizing radioiodinated zopiclone

Taha

Nour

Mamdouh

et al. 2023

International Journal of Pharmaceutics: X

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“…The growth parameters were measured after the feeding experiment according to the following formulas (Hajiahmadian et al, 2012; Mani & Ebrahimi, 2021):

Weight gain (WG) = Wf (normalg) - Wi (normalg)

Weight gain (%) = [Wf (normalg) - Wi (normalg) / Wi (normalg)] \times 100

Feed conversion ratio (FCR) = Total feed intake / Wf (normalg) - Wi (normalg)

Specific growth rate (SGR) = 100 (\ln Wf - \ln Wi) / T

Thermal growth coefficient (TGC) = 100 \times [Wf 1 / 3 - Wi 1 / 3 / (T) \times ° C]

\begin{matrix} left Condition of factor ()(, CF) ()(%) goodbreak= (][, total length ()(, cm) / fish weight ()(, g)) goodbreak\times 100 \end{matrix}

\begin{matrix} left Protein efficiency ratio ()(, PER) goodbreak= wet \end{matrix}

…”

Section: Methodsmentioning

confidence: 99%

“…The growth parameters were measured after the feeding experiment according to the following formulas (Hajiahmadian et al, 2012;Mani & Ebrahimi, 2021)…”

Section: Growth Parametersmentioning

confidence: 99%

Probiotic effects of the fungi,Aspergillus nigeron growth, immunity, haematology, intestine fungal load and digestive enzymes of the common carp,Cyprinus carpio

Jasim

Abdelbasset

Shichiyakh

et al. 2022

Aquaculture Research

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The present study was conducted to investigate the probiotic role of the unicellular fungi, Aspergillus niger on growth performance, immunity, haematology and digestive enzymes in common carp, Cyprinus carpio. One non‐supplemented group (T0) was considered as control and two groups fed the fungi including T1 (fish supplemented with diet containing 1 × 103 A. niger) and T2 (fish supplemented with diet containing 1 × 106 A. niger) considered as the experimental treatments in three replicates. Fish were fed experimental diets for 60 days. The survival rate and growth parameters (final length and weight, weight gain (%), thermal growth coefficient (TGC), protein efficiency ratio and lipid efficiency ratio) significantly increased in A. niger supplemented fish compared with control (p < 0.05). The values of FCR (feed conversion ratio) and CF (condition of factor) significantly decreased after feeding experiment in fish of T2 and T1 compared with control (p < 0.05). The plasma levels of lysozyme and total immunoglobulin significantly elevated in A. niger supplemented groups compared with control (p < 0.05). The RBC (red blood cell) counts, Hb (haemoglobin) concentrations, MCH (mean corpuscular haemoglobin) and MCV (mean corpuscular volume) values significantly increased in A. niger supplemented fish compared with control (p < 0.05). The WBC (white blood cell) and Hct (haematocrit) value were higher in fish of T2 compared with control (p < 0.05). The number of neutrophils significantly increased in the treatment, T2 compared with control (p < 0.05). Furthermore, the lymphocyte counts significantly increased in A. niger supplemented fish compared with control (p < 0.05). The body composition of fish showed increases in the fish dry matter and protein content and decreases in lipid content of T1 and T2 groups compared with control (p < 0.05). The digestive enzymes (protease, trypsin, amylase, lipase and alkaline phosphatase), apparent protein ad lipid digestibility significantly increased in response to dietary level of 1 × 106 A. niger compared with control (p < 0.05). The supplementation of fish with A. niger also prompted the load of the fungi in intestine (p < 0.05). The results of the present study confirmed the probiotic role of A. niger in common carp, since it improved growth, immunity, digestion and the fish haematology.

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“…To determine the optimal values for the independent variables, the desirability function method was employed. This approach entailed evaluating the desirability index for each response variable and then combining all response variables into a single desirability function that ranged from 0 to 1, indicating the ideal values of the independent parameters [ 51 ].…”

Section: Methodsmentioning

confidence: 99%

Combining the potential of 3D printed buccal films and nanostructured lipid carriers for personalised cannabidiol delivery

Abdella,

Kim,

Afinjuomo

et al. 2023

Drug Deliv. and Transl. Res.

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Cannabidiol (CBD) has been recognized for its numerous therapeutic benefits, such as neuroprotection, anti-inflammatory effects, and cardioprotection. However, CBD has some limitations, including unpredictable pharmacokinetics and low oral bioavailability. To overcome the challenges associated with CBD delivery, we employed Design of Experiments (DoE), lipid carriers, and 3D printing techniques to optimize and develop buccal film loaded with CBD-NLCs. Three-factor Box-Behnken Design was carried out to optimise the NLCs and analyse the effect of independent factors on dependent factors. The emulsification-ultrasonication technique was used to prepare the NLCs. A pressure-assisted micro-syringe printing technique was used to produce the films. The produced films were studied for physicochemical, and mechanical properties, release profiles, and predicted in vivo performance. The observed particle size of the NLCs ranged from 12.17 to 84.91 nm whereas the PDI varied from 0.099 to 0.298. Lipid and sonication time positively affected the particle size whereas the surfactant concentration was inversely related. CBD was incorporated into the optimal formulation and the observed particle size, PDI, and zeta potential for the CBD-NLCs were 94.2 ± 0.47 nm, 0.11 ± 0.01 and − 11.8 ± 0.52 mV. Hydroxyethyl cellulose (HEC)-based gel containing the CBD-NLCs was prepared and used as a feed for 3D printing. The CBD-NLCs film demonstrated a slow and sustained in vitro release profile (84. 11 ± 7.02% in 6 h). The predicted AUC0–10 h, Cmax, and Tmax were 201.5 µg·h/L, 0.74 µg/L, and 1.28 h for a film with 0.4 mg of CBD, respectively. The finding demonstrates that a buccal film of CBD-NLCs can be fabricated using 3D printing. Graphical Abstract

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Equally weighted multivariate optimization of feeding rate for sub‐yearling great sturgeon (Huso huso) using desirability function model

Cited by 6 publications

References 45 publications

Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity & in vivo biodistribution utilizing radioiodinated zopiclone

Cod liver oil nano-structured lipid carriers (Cod-NLCs) as a promising platform for nose to brain delivery: Preparation, in vitro optimization, ex vivo cytotoxicity & in vivo biodistribution utilizing radioiodinated zopiclone

Probiotic effects of the fungi,Aspergillus nigeron growth, immunity, haematology, intestine fungal load and digestive enzymes of the common carp,Cyprinus carpio

Combining the potential of 3D printed buccal films and nanostructured lipid carriers for personalised cannabidiol delivery

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