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Background Poor sleep quality is now a cause of sexual dysfunction. Aim To investigate variations in sleep quality among patients with different types of premature ejaculation (PE) and a control group. Methods Patients with PE were categorized into groups according to 4 types: lifelong (LPE), acquired (APE), variable (VPE), and subjective (SPE). Basic demographic information about the participants was first collected, and then clinical data were obtained. Outcomes Outcomes included the 5-item International Index of Erectile Function, Premature Ejaculation Diagnostic Tool, 7-item Generalized Anxiety Disorder, 9-item Patient Health Questionnaire, Pittsburgh Sleep Quality Index, self-estimated intravaginal ejaculation latency time (minutes), and sleep monitoring parameters obtained from a wearable device (Fitbit Charge 2). Results A total of 215 participants were enrolled in the study, of which 136 patients with PE were distributed as follows: LPE (31.62%), APE (42.65%), VPE (10.29%), and SPE (15.44%). Subjective scales showed that patients with APE were accompanied by a higher prevalence of erectile dysfunction, anxiety, and depression, as well as poorer sleep quality (assessed by the Pittsburgh Sleep Quality Index). The results of objective sleep parameters revealed that average durations of sleep onset latency (minutes) and wake after sleep onset (minutes) in patients with APE (mean ± SD; 20.03 ± 9.14, 55 ± 23.15) were significantly higher than those with LPE (15.07 ± 5.19, 45.09 ± 20.14), VPE (13.64 ± 3.73, 38.14 ± 11.53), and SPE (14.81 ± 4.33, 42.86 ± 13.14) and the control group (12.48 ± 3.45, 37.14 ± 15.01; P < .05). The average duration of rapid eye movement (REM; minutes) in patients with APE (71.34 ± 23.18) was significantly lower than that in patients with LPE (79.67 ± 21.53), VPE (85.93 ± 6.93), and SPE (80.86 ± 13.04) and the control group (86.56 ± 11.93; P < .05). Similarly, when compared with the control group, patients with LPE had significantly longer durations of sleep onset latency and wake after sleep onset and a significantly shorter duration of REM sleep. Clinical Implications Our study suggests that clinicians should pay attention not only to male physical assessment but also to mental health and sleep quality. Strengths and Limitations This study suggests that changes in sleep structure occur in patients with PE, which may provide some direction for future research. However, the cross-sectional study design does not allow us to conclude that sleep is a risk factor for PE. Conclusion After controlling for traditional parameters such as age, erectile dysfunction, anxiety, and depression, sleep parameters are independently associated with PE. Patients with APE and LPE show significant alterations in sleep parameters, with patients with APE having notably poorer sleep quality, whereas patients with VPE and SPE have sleep parameters similar to controls.
Background Poor sleep quality is now a cause of sexual dysfunction. Aim To investigate variations in sleep quality among patients with different types of premature ejaculation (PE) and a control group. Methods Patients with PE were categorized into groups according to 4 types: lifelong (LPE), acquired (APE), variable (VPE), and subjective (SPE). Basic demographic information about the participants was first collected, and then clinical data were obtained. Outcomes Outcomes included the 5-item International Index of Erectile Function, Premature Ejaculation Diagnostic Tool, 7-item Generalized Anxiety Disorder, 9-item Patient Health Questionnaire, Pittsburgh Sleep Quality Index, self-estimated intravaginal ejaculation latency time (minutes), and sleep monitoring parameters obtained from a wearable device (Fitbit Charge 2). Results A total of 215 participants were enrolled in the study, of which 136 patients with PE were distributed as follows: LPE (31.62%), APE (42.65%), VPE (10.29%), and SPE (15.44%). Subjective scales showed that patients with APE were accompanied by a higher prevalence of erectile dysfunction, anxiety, and depression, as well as poorer sleep quality (assessed by the Pittsburgh Sleep Quality Index). The results of objective sleep parameters revealed that average durations of sleep onset latency (minutes) and wake after sleep onset (minutes) in patients with APE (mean ± SD; 20.03 ± 9.14, 55 ± 23.15) were significantly higher than those with LPE (15.07 ± 5.19, 45.09 ± 20.14), VPE (13.64 ± 3.73, 38.14 ± 11.53), and SPE (14.81 ± 4.33, 42.86 ± 13.14) and the control group (12.48 ± 3.45, 37.14 ± 15.01; P < .05). The average duration of rapid eye movement (REM; minutes) in patients with APE (71.34 ± 23.18) was significantly lower than that in patients with LPE (79.67 ± 21.53), VPE (85.93 ± 6.93), and SPE (80.86 ± 13.04) and the control group (86.56 ± 11.93; P < .05). Similarly, when compared with the control group, patients with LPE had significantly longer durations of sleep onset latency and wake after sleep onset and a significantly shorter duration of REM sleep. Clinical Implications Our study suggests that clinicians should pay attention not only to male physical assessment but also to mental health and sleep quality. Strengths and Limitations This study suggests that changes in sleep structure occur in patients with PE, which may provide some direction for future research. However, the cross-sectional study design does not allow us to conclude that sleep is a risk factor for PE. Conclusion After controlling for traditional parameters such as age, erectile dysfunction, anxiety, and depression, sleep parameters are independently associated with PE. Patients with APE and LPE show significant alterations in sleep parameters, with patients with APE having notably poorer sleep quality, whereas patients with VPE and SPE have sleep parameters similar to controls.
Background Red ginseng (RG) is a traditional herb commonly used in China, Korea, and other East Asian countries. Recently, it has demonstrated a better clinical value in men’s reproductive health (MRH). The present review aimed to examine the effects of RG treatment on MRH. Results Overall, 42 articles related to RG application in MRH were reviewed, of which 31 were animal experiments and 11 were clinical studies. Furthermore, this review analyzed the use of RG in some male reproductive diseases in clinical trials and determined the associated mechanisms of action. The mechanism of action of RG in MRH may be related to oxidative stress, regulation of sex hormones and spermatogenesis-related proteins, and anti-inflammation. Conclusions The application of RG for the treatment of male infertility, erectile dysfunction, and prostate diseases has the potential to contribute to MRH.
YouTube'a gönderilen erken boşalma (PE) ile ilgili Türkçe videoların bilgilendirici değerini değerlendirmek. Youtube.com'da 15-16 Ağustos 2023 tarihleri arasında yayınlanan, "erken boşalma" anahtar kelimesi ile erişilen, Türkçe yayınlanan ve arama sonuçlarında standart bir alaka düzeyi sırasına göre görüntülenen ilk 103 video incelenmiştir. Ürün tanıtımlarının yapıldığı videolar çalışma dışında tutulmuştur. Videoların bilgi içeriğinin kalitesi, DISCERN puanlaması kullanılarak değerlendirildi. Elde edilen veriler IBM SPSS for Windows 21 kullanılarak analiz edilmiştir. Dahil edilme kriterlerini karşılayan 100 videonun %87'sinin sağlık çalışanları tarafından yüklendiği belirlendi. Videolar içeriklerine göre incelendiğinde yayınlanan videoların konularının öncelikli olarak teşhis ve tedavi odaklı olduğu belirlendi. Videoların toplam süresi 521,37 dakikadır (3,49 (0,34;36,06)). Toplam izlenme sayısı 17165500 (43000(1000;2100000)) olurken, toplam beğeni sayısı 52093,38(279.0000(1;2200)) olarak belirlendi. Videoların aylık ortalama beğeni sayısı 15.9375(2.4329;91.8750), aylık görüntülenme ortanca değeri ise 2512.5000(500.0000;15228.0833) dir.. Videoların 14'ü kötü, 10'u orta ve 76'sı yüksek içerik kalitesine sahipti. DISCERN puanları ile aylık ortalama beğeni ve görüntüleme sayısı arasında pozitif bir korelasyon vardı. Doktorlar tarafından yüklenen videolar yüksek bir DISCERN puanına sahipken, diğer videoların içerik kalitesi orta ile zayıf arasındaydı. Video uzunluğu ile izlenme sayısı (r=0,217 p=0,030) ve video beğeni sayısı (r=0,581 p<0,001) arasında pozitif korelasyon bulundu. PE ile ilgili Türkçe You Tube videolarının büyük bir kısmı Sağlık profesyonellerince yüklenmiş, içerik güvenirlik kalitesi genel olarak yüksek videolardır. Kullanıcılar çoğunlukla içerik güvenirlik kalitesi yüksek ve uzun videoları daha çok izlemekte ve beğenmektedirler.
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