Erectile dysfunction as a predictor of two-year prognosis in acute myocardial infarction

Apostolović, Svetlana; Stanojević, Dragana; Janković–Tomašević, Ružica; Šalinger-Martinović, Sonja; Kostić, Tomislav; Perišić, Zoran

doi:10.5603/cj.a2017.0006

Cited by 4 publications

(3 citation statements)

References 25 publications

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“…In patients presented with acute MI, the presence of ED was found to be associated with and adverse outcome. ED was found to be a significant and an independent predictor of death and re-hospitalization in men presented with acute MI 23 …”

Section: Discussionmentioning

confidence: 90%

Erectile dysfunction severity as a predictor of left main and/or three-vessel disease in acute coronary syndrome patients

Al-Daydamony

Shawky

Tharwat

2018

Indian Heart Journal

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BackgroundCoronary artery disease (CAD) is a leading cause of morbidity and death. Early diagnosis of patients with left main and/or three-vessel disease (LM/3VD) among acute coronary syndrome (ACS) patients is beneficial. The relation between erectile dysfunction (ED) and cardiovascular diseases was previously noticed. The aim of our work was to find out if the severity of ED could predict the presence of LM/3VD in ACS patients.Patients and methodsEighty-five male patients with ACS were included in the study. Clinical assessment, estimation of international index of erectile function (IIEF) score, and coronary angiography were performed in all patients. Gensini score was calculated to assess the severity of CAD. Based on IIEF score, the patients were divided into two groups: Group 1: patients with mild or no ED (IIEF score ≥17), Group 2: patients with moderate or severe ED (IIEF score <17).ResultsPatients with IIEF score <17 had significantly higher prevalence of LM CAD (4.3% versus 18.4%, p = 0.035), 3VD (17% versus 39.5%, p = 0.021) and LM/3VD (21.3% versus 55.3%, p = 0.0012), as well as higher mean Gensini score (23.5 ± 10.8 versus 34.1 ± 12.7, p = 0.0001). The independent predictors of LM/3VD in order of significance were: age, heart rate, IIEF <17, Killip class >1, and ST-depression or ST-elevation in lead aVR ≥1 mV. There was a significant negative correlation between IIEF score and Gensini score (r = −0.383, p = 0.0003).ConclusionThe presence of moderate or severe ED in men with ACS is associated with higher Gensini score and more incidence of LM/3VD. IIEF score <17 was an independent predictor of LM/3VD.

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Section: Discussionmentioning

confidence: 90%

Erectile dysfunction severity as a predictor of left main and/or three-vessel disease in acute coronary syndrome patients

Al-Daydamony

Shawky

Tharwat

2018

Indian Heart Journal

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“…Furthermore, a study by Nguyen et al [1] found that patients exposed to ADT had a higher risk of diabetes, coronary heart disease, myocardial infarction, and sexual dysfunction. These long-term side effects are well-recognized stand-alone or surrogate factors associated with vascular disease, which has been directly linked to the pathogenesis of some forms of dementia [9,25,26]. In combination with a potential direct biopsychological influence of ADT, these side effects may contribute to the increased risk of developing dementia in patients undergoing ADT.…”

Section: Discussionmentioning

confidence: 99%

Risk of Dementia and Depression in Young and Middle-aged Men Presenting with Nonmetastatic Prostate Cancer Treated with Androgen Deprivation Therapy

Tully

Nguyen

Herzog

et al. 2021

European Urology Oncology

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“…Отримані дані узгоджуються з результатами тих досліджень, у яких показано, що зниження концентрацій тестостерону у чоловіків супроводжується збільшенням смертності, поширеності атеросклеро-зу та ішемічної хвороби серця, збільшення товщини комплексу інтима-медіа в сонних артеріях, а також маси жирової тканини і поширеності порушень глікемічного профілю. Незалежні чинники ризику для ЕД і серцево-судинних захворювань є добре відомими -вік, куріння, ЦД, гіпертензія, дисліпідемія, депресія, ожиріння та малорухомий спосіб життя [10]. Показано, що одні й ті самі чинники ризику розвитку захворювань коронарних артерій є також чинниками ризику розвитку ЕД [6].…”

Section: рис 2 розподіл пацієнтів за ступенем еректильної дисфункціїunclassified

Myocardial Infarction in Young Men, Features of Clinical Course and State of Erectile Function

Makukha¹,

Kravchenko²,

Andrieiev

et al. 2021

Clin. and prev. med.

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Aim of the study is to determine the features of the clinical course and study the state of erectile function in young men who have suffered MI. 112 male patients of Caucasian race of the Ukrainian population under the age of 50 (mean 43.21±2.8 years) who have had MI were examined. Clinical and anamnestic data indicate the similarity of young men who have suffered MI with their peers. Yes, there are no significant differences in the percentage of smokers, burdened family history. Analysis of erectile dysfunction, according to the IIEF-5 questionnaire, indicates the presence of problems in young men who have suffered MI. All examined patients were admitted to the hospital within 12 hours from the first symptoms of MI, which allowed to perform urgent coronary angiography with subsequent endovascular intervention - stenting. According to the cardiac ventriculography, about half of the patients (50 - 44.6%) had a three-vessel disease despite the young age. One third of patients received as a beta-blocker the new class of drug of the 3rd generation - nebivalol (37 patients - 33.0%), which is important for young patients, as this drug has no adverse effects on erectile function in men. 44 (39.3%) received bisoprolol, a more common long-term beta-blocker. 31 patients had contraindications to beta-blockers. Conclusions. Myocardial infarction in young men was characterized by a high frequency of anginal form of the clinical course, multivessel disease of the coronary arteries, lipid profile disorders, a high proportion of patients with erectile dysfunction. Erectile dysfunction in young men is an early marker of coronary heart disease. All men with ED should undergo a thorough cardiac examination to determine lipid profile and testosterone levels. In patients with coronary heart disease, the symptoms of ED should be actively identified, initiate targeted lifestyle changes to reduce risks, as well as taken into account when choosing drugs for medical treatment.

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Erectile dysfunction as a predictor of two-year prognosis in acute myocardial infarction

Cited by 4 publications

References 25 publications

Erectile dysfunction severity as a predictor of left main and/or three-vessel disease in acute coronary syndrome patients

Erectile dysfunction severity as a predictor of left main and/or three-vessel disease in acute coronary syndrome patients

Risk of Dementia and Depression in Young and Middle-aged Men Presenting with Nonmetastatic Prostate Cancer Treated with Androgen Deprivation Therapy

Myocardial Infarction in Young Men, Features of Clinical Course and State of Erectile Function

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