Erkrankungen der peripheren Nerven

Krücke, W.

doi:10.1007/978-3-642-48003-4_1

Cited by 15 publications

(2 citation statements)

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“…In this way, basket-like formations ( fig. 2 b) developed compa- rable with the 'ResidualknaueT described by Kriicke (13), In all cases, particularly those with a long-standing case history, a marked fibrosis of the nerve fibers between both muscle layers ( fig. 3b) was recognized.…”

Section: Resultsmentioning

confidence: 99%

Intramural Ganglion Cell Degeneration in Inflammatory Bowel Disease

Oehmichen

Reifferscheid²

1977

Digestion

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Comparable histologic alterations of intramural nervous tissue were reported in various diseases of the small and large intestine. In 6 cases, an intestinal obstruction was present which led to secondary intramural inflammation. The obstruction was induced by the spastic segment in Hirschsprung’s disease (3 cases), by rectal atresia (2 cases) and by postoperative ischemic damage to the intestinal wall (1 case). In 4 other patients, the inflammation was predominant. The diseases considered were necrotizing enterocolitis (1 case), membranous enteritis (1 case) and Crohn’s disease (2 cases). On the one hand, inflammatory infiltration composed primarily of lymphocytes was observed histologically in various degrees proximal to the obstruction in all cases. On the other, comparable alterations were found in sputtering of nerve fibers and deterioration of nerve cells (degenerative alterations) in the plexus myentericus as well as hyperplasia and hyperchromasia of ganglion cells, Schwann cell proliferation and fibrosis in nerve fibers (reactive alterations). Until now such alterations were only observed in Chagas’ disease and in ulcerative colitis, especially complicated by toxic megacolon. It is suspected that the neurodegenerative alterations in these diseases are toxically induced.

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Section: Resultsmentioning

confidence: 99%

Intramural Ganglion Cell Degeneration in Inflammatory Bowel Disease

Oehmichen

Reifferscheid²

1977

Digestion

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“…Spinal nerves are usually monofascicular with epi-perineural covering, which accounts for their sonographic appearance consisting of hypoechoic oval structure surrounded by hyperechoic perineurial rim (Haun et al, 2010). Autopsy studies in early AIDP have demonstrated that initial lesion is inflammatory oedema predominating in spinal roots and ventral rami of spinal nerves (Haymaker and Kernohan, 1949, Krücke, 1955, Berciano et al, 2017). Intriguingly, such topography of lesions concurs with that originally found in AMAN, literally reported as follows (McKhann et al, 1993): “The most proximal site of fibre degeneration was in the proximal or mid-ventral roots; the proportion of degenerating fibres increased distally toward the ventral root exit from the dura.…”

Section: Discussionmentioning

confidence: 99%