The focus of enterprise resource planning (ERP) adoption among Higher Education Institutions (HEIs) has attracted the interest of many Information System (IS) researchers. As a result of its great business values, the adoption of ERP solution is increasingly growing within HEIs. However, very limited studies have focused their attention towards understanding the determinants of ERP adoption among HEIs, especially in Egypt. Furthermore, the adoption of ERP systems in Egypt is still in the beginning stage with no many adopters among HEIs. Therefore, this study aims to fill in the gap by investigating technological, organizational and environmental (TOE) framework among HEIs. Accordingly, the objective of this research paper is mainly trying to introduce a conceptualized research model that can be used to examine ERP adoption among HEIs. This article contributes to the development of theoretical framework of the ERP adoption to explain the competitive advantage within HEIs by using TOE framework. The current study will provide guidelines to ERP providers, the government, and HEIs in Egypt to accelerate ERP adoption.