Erratum to “Persistent symptoms and decreased health-related quality of life after symptomatic pediatric COVID-19: A prospective study in a Latin American tertiary hospital” [Clinics. 2021;76:e3511]

Fink, Thais T.; Marques, Heloísa Helena de Sousa; Gualano, Bruno; Lindoso, Lívia; Bain, Vera; Astley, Camilla; Martins, Fernanda; Matheus, Denise; Matsuo, Olivia Mari; Suguita, Priscila; Trindade, Vitor; Paula, Camila Sanson Yoshino de; Farhat, Sylvia Costa Lima; Palmeira, Patricia; Leal, Gabriela Nunes; Suzuki, Lisa; Filho, Vicente Odone; Carneiro‐Sampaio, Magda; Duarte, Alberto J. S.; Antonângelo, Leila; Battistella, Linamara Rizzo; Polanczyk, Guilherme; Pereira, Rosa Maria Rodrigues; Carvalho, Carlos Roberto Ribeiro; Buchpiguel, Carlos Alberto; Buchpiguel, Carlos Alberto; Seelaender, Marília; Silva, Clóvis A.; Pereira, Maria Fernanda Bádue

doi:10.1016/j.clinsp.2022.100024

Cited by 7 publications

(24 citation statements)

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“…Nine of the 27 studies included an uninfected control group. [5][6][7][8][18][19][20][21][22] Six studies compared the proportion of children and adolescents with persistent symptoms in those with and without evidence of prior SARS-CoV-2 infection. 5,8,[19][20][21][22] The difference in proportions varied between -0.5% and 13.2% (median 3.0%, IQR 1.4%-3.6%) (Fig.…”

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confidence: 99%

“…Two studies did not report the proportion of children affected by long COVID symptoms in the control group. 6,18 Although many studies included a control group, they all had other deficiencies meaning their results need to be viewed with caution. Many had low response rates or differences in response and inclusion rates between children with and without SARS-CoV-2 infection (Table, Supplemental Digital Content 1, http:// links.lww.com/INF/E684).…”

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confidence: 99%

“…We identified 27 studies (13 cross-sectional studies, 5–17 9 prospective cohort studies, 18–26 4 case series 27–30 and 1 retrospective cohort study 31 ) investigating persistent symptoms in a total of 34,664 SARS-CoV-2-infected and 38,988 uninfected children and adolescents. The number of children in each study varied from 5 to 30,117 [median 105, interquartile range (IQR) 30–859].…”

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confidence: 99%

“…Two studies did not report the proportion of children affected by long COVID symptoms in the control group. 6,18…”

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confidence: 99%

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The Challenge of Studying Long COVID: An Updated Review

Zimmermann

Pittet

Curtis

2022

Pediatric Infectious Disease Journal

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Accurately determining the risk of long COVID is challenging. Existing studies in children and adolescents have considerable limitations and distinguishing long-term SARS-CoV-2 infection-associated symptoms from pandemic-related symptoms is difficult. Over half of individuals in this age group, irrespective of COVID-19, report physical and psychologic symptoms, highlighting the impact of the pandemic. More robust data is needed to inform policy decisions.

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confidence: 99%

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confidence: 99%

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confidence: 99%

“…Two studies did not report the proportion of children affected by long COVID symptoms in the control group. 6,18…”

mentioning

confidence: 99%

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The Challenge of Studying Long COVID: An Updated Review

Zimmermann

Pittet

Curtis

2022

Pediatric Infectious Disease Journal

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“…7-11 This difference may have resulted because the current study treated symptom duration as a continuous measure or because the current cohort included a large number of infants and toddlers with mild symptoms. In contrast, many prior studies have focused on adolescents, 9,22 included hospitalized patients, 23,24 or focused on symptoms persisting beyond 12 weeks. 10,25 The results did display a strong association between duration of fatigue and child obesity, an important medical factor reported in previous studies of SARS-CoV-2.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Symptom Duration Between Children With SARS-CoV-2 and Peers With Other Viral Illnesses During the COVID-19 Pandemic

Hicks

2023

Clin Pediatr (Phila)

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Some children and young people (CYP) with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) experience persistent symptoms, commonly called “long COVID.” It remains unclear whether symptoms of SARS-CoV-2 persist longer than those of other respiratory viruses, particularly in young children. This cross-sectional study involved 372 CYP (0-15 years) tested for SARS-CoV-2. Character and duration of symptoms (cough, runny nose, sore throat, rash, diarrhea, vomiting, sore muscles, fatigue, fever, loss of smell) were compared between CYP with a positive test (n = 100) and those with a negative test (n = 272), while controlling for medical/demographic covariates. The average duration of symptoms for CYP with a positive SARS-CoV-2 test (8.5 ± 10 days) did not differ from that of CYP with a negative test (7.2 ± 5 days, P = .71, d = 0.046). A positive SARS-CoV-2 test did not increase the risk (36/372, 10%) of symptoms persisting for ≥3 weeks (odds ratio = 0.96, 95% confidence interval = 0.45-2.0). These results suggest CYP with non-SARS-CoV-2 infections experience a similar duration of symptoms as peers with SARS-CoV-2 infection.

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COVID-19 related headaches: epidemiology, pathophysiology, impacts, and management

Aiyegbusi

2023

Current Opinion in Neurology

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Purpose of review This is an expert overview of the recent literature on the nature, epidemiology, pathophysiology, impact, and management of COVID-19 related headache, in the acute phase of infection and in post-COVID-19 syndrome. Recent findings Headache is one of the commonest symptoms of COVID-19 during acute infection and it is often experienced by individuals who go on to develop long COVID. There is a higher prevalence of headache in individuals with long COVID who contracted the Delta variant than in those who were infected with the Wuhan or Alpha variants. Headaches related to COVID-19 infection are commoner and may be more intense in women. There are indications that presence of headache might indicate a more benign COVID-19 infection and a better chance of survival. However, the impact of COVID-19 related headache could be substantial leading to poor quality of life in individuals affected. Headache that changes in its nature in terms of frequency and severity should be investigated to exclude cerebrovascular complications. There are promising new therapies for its treatment, but further research is needed. Summary The findings of this review can promote a better understanding of COVID-19 related headache and guide clinicians in the management of patients.

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Erratum to “Persistent symptoms and decreased health-related quality of life after symptomatic pediatric COVID-19: A prospective study in a Latin American tertiary hospital” [Clinics. 2021;76:e3511]

Cited by 7 publications

References 0 publications

The Challenge of Studying Long COVID: An Updated Review

The Challenge of Studying Long COVID: An Updated Review

Comparison of Symptom Duration Between Children With SARS-CoV-2 and Peers With Other Viral Illnesses During the COVID-19 Pandemic

COVID-19 related headaches: epidemiology, pathophysiology, impacts, and management

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