Erythema multiforme: Clinical spectrum and immunopathogenesis

Ibuprofen-Induced Pancytopenia and Erythema Multiforme in an Elderly Female Patient

“…The estimate of mucous membrane involvement is typically around 25 to 60%; the oropharynx, lips, and conjunctiva are the most frequently and severely affected. The most well-recognized presentation is the abrupt onset of symmetrically distributed erythematous macules and papules that grow into bullous, gyrate, vesicular, annular, or iris-shaped lesions that may become hemorrhagic [7]. Our patient reported days of ulcerated lesions of the oral cavity with positive Nikolsky's sign followed by symmetric targetoid skin lesions on the limbs.…”