Erythema Multiforme Exudativum (The Stevens-Johnson Syndrome)

Dresner, Ellis

doi:10.1016/s0140-6736(49)91604-9

Cited by 16 publications

(4 citation statements)

References 31 publications

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“…This case demonstrates extensive involvement of the gastrointestinal tract secondary to SJS, and is the first reported pediatric case in which both the upper and lower gastrointestinal tracts are involved. Since its first description in 1949, 16 we have been able to identify only 14 pediatric cases of SJS/TEN with gastrointestinal involvement, five of which had isolated esophageal involvement (Table 1). [17][18][19][20][21][22][23][24][25][26][27] These five cases experienced the most common presentation of gastrointestinal tract involvement in children: progressive dysphagia weeks to years after the acute illness due to an esophageal stricture.…”

Section: Discussionmentioning

confidence: 99%

<p>Severe Gastrointestinal Involvement in Pediatric Stevens-Johnson Syndrome: A Case Report and Review of the Literature</p>

Bechek¹,

García²,

Chiou³

2020

CEG

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Stevens-Johnson syndrome and toxic epidermal necrolysis form a rare but severe disease spectrum characterized by widespread epidermal detachment. Gastrointestinal manifestations of the disease, however, are rarely described in the pediatric literature and have a high mortality among adults. There are limited data on the treatment of these cases, with conflicting evidence regarding the benefit of steroids, IVIG, or other immunosuppressive agents. We review previous instances of gastrointestinal involvement in children and report the case of a previously healthy 13-year-old who presented with the typical ocular and skin findings of Stevens-Johnson syndrome, subsequently developed severe life-threatening diarrhea, and was found to have severe esophagitis, duodenitis, and colitis on endoscopic evaluation. Treatment was initiated with an immediate, short course of steroids along with early introduction of an enteral diet via nasogastric tube, and resulted in full gastrointestinal recovery. This case highlights successful medical treatment of the first reported pediatric case of SJS/TEN with both upper and lower gastrointestinal tract involvement.

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Section: Discussionmentioning

confidence: 99%

<p>Severe Gastrointestinal Involvement in Pediatric Stevens-Johnson Syndrome: A Case Report and Review of the Literature</p>

Bechek¹,

García²,

Chiou³

2020

CEG

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“…The first reports of gastrointestinal involvement in SJS/TEN were via case reports in 1949 and 1956 where an acute and recurrent history, respectively, of abdominal pain and exudative diarrhea in a patient with SJS was presumed to be associated with the disease [36,37]. No focused discussions on the gastrointestinal manifestations of SJS/TEN occurred in the literature until 1974, when esophageal stricture and resultant progressive dysphagia were described as late complications of SJS/TEN.…”

Section: Gastrointestinal/hepaticmentioning

confidence: 99%

Complications of Stevens–Johnson syndrome beyond the eye and skin

Saeed

Mantagos

Chodosh

2016

Burns

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“…), larvae on the trees. Dresner (1949) published an extensive piece of work on Beauveria bassiana which included the host range of the fungus, artificial culture methods, moisture requirements, and labora tory and field applications of the spores. Beauveria bassiana was re covered by Steinhaus (1952) from cadavers of European corn borer larvae sent to California from Iowa and Ohio.…”

Section: Beauveriamentioning

confidence: 99%