Erythrocyte sedimentation rate as a marker for coronary heart disease

Abstract

BackgroundPatients with angina pectoris or myocardial infarction frequently present without evidence of cardiac-specific heart enzymes by laboratory analysis or specific pathologic electro-cardiogram findings. The current study analyzed the efficacy of the erythrocyte sedimentation rate as an additional potential indicator for coronary heart disease, the aim being to enable quicker identification of patients with angina pectoris or myocardial infarction so that they can be more rapidly treated.MethodsPatients with angina pectoris or myocardial infarction who had undergone a heart catheter examination were included in the study. The diagnosis of acute coronary heart disease was made by the physician who performed coronary angiography. Patients without coronary heart disease were used as a control group. The erythrocyte sedimentation rate was measured in all patients. Patients with angina pectoris or myocardial infarction and an inflammatory or tumor disease were excluded.ResultsThe erythrocyte sedimentation rate was prolonged in 79 (58.09%) of 136 patients; 69 (50.74%) patients (95% confidence interval ±8.4%, 42.34%–59.14%) had coronary heart disease and a prolonged erythrocyte sedimentation rate. The erythrocyte sedimentation rate was prolonged in ten (7.35%) patients (95% confidence interval ±4.39%, 2.96%–11.74%) without coronary heart disease by coronary angiography. The specificity of the erythrocyte sedimentation rate for coronary heart disease was 70.59% and the sensitivity was 67.65%.ConclusionErythrocyte sedimentation rate may be a useful additional diagnostic criterion for coronary heart disease.

ESR rate can be a marker for coronary artery disease

“…Prakash et al2 have pointed to conflicting reports in the literature documenting the tendency of patients with periodontitis to develop anemia. Hence, this study was undertaken to assess whether periodontitis can cause an anemic state by evaluating and comparing the red blood cell count and levels of hemoglobin, hematocrit, ESR, serum iron, and serum ferritin between subjects with and without periodontitis, anemia, rheumatoid arthritis, and other hematologic conditions 1. However, this study shows that there is no statistically significant difference between rates of ESR in men and women.…”

“…The aim of Yayan’s1 study was to utilize the erythrocyte sedimentation rate (ESR) as a rapid guide to identify patients with acute coronary syndrome (ACS) or myocardial infarction. ESR is arguably a nonspecific biomarker which is elevated in almost every condition.…”

“…Finally, Yayan et al showed that ESR was prolonged in patients with CAD who had undergone a percutaneous coronary intervention procedure, and suggest that ESR may be a useful additional diagnostic criterion for CAD 1. Arguably, a study should be conducted to check inflammatory biomarkers in the absence of confounding factors which may be misleading about the patient, ie, fever, an altered immune system leading to hypothermia, and underlying medical conditions, such as inflammatory bowel disease, rheumatoid arthritis, or even systemic lupus erythematosus.…”

The correlation between preoperative erythrocyte sedimentation rate and postoperative outcome in adult cardiac surgery

“…Manchon et al16 (1988) reported the high recurrence of issues (95%) such as infection, malignancy and inflammation in patients with ESR levels >70 mm/h. Yayan17 showed that ESR usually is high in patients with coronary heart disease, and this may be due to the inflammatory etiology of coronary heart disease. Togan et al7 similarly demonstrated that in male patients who had undergone CABG surgery, the elevated preoperative ESR can bring about midterm postoperative adverse events such as morbidity and mortality.…”

Spiroergometrie in der erweiterten flugmedizinischen kardiovaskulären Beurteilung

“…Ein Verfahren, das problemlos mit der Ergometrie verbunden werden kann, bislang jedoch in der Kardiologie wenig zur Anwendung gekommen ist, ist die Spiroergometrie. Hier wird neben dem Belastungs-EKG kontinuierlich das Atemvolumen und über in-und exspiratorische Sauerstoffund Kohlendioxidkonzentrationen auch die Sauerstoffaufnahme ( Blutsenkung und CRP sind zwar ebenfalls mit einem erhöhten kardiovaskulären Risiko assoziiert, sind jedoch sehr unspezifisch und auch bei banalen Infekten erhöht [16,17]. Im Fall der TSH-Bestimmung sind die Hypothyreose sowie die Hyperthyresose mit einem erhöhten kardiovaskulären Risiko assoziiert [18,19].…”