Erythrocytosis and Hypernephroma

Thorling, Eivind B.; Ersbak, J

doi:10.1111/j.1600-0609.1964.tb00004.x

Cited by 13 publications

(1 citation statement)

References 14 publications

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“…The animals were described in detail by Poul Hansen in 1963. The analysis was described more exhaustively in a previous paper (Thorling & Ersbak 1964). The test material (serum, urine) was given subcutaneously for two consecutive days in doses of 2 ml.…”

Section: Eivind B Thorlingmentioning

confidence: 99%

Erythropoietin in Serum from Patients with Leucosis Assays in Starved Rats

Thorling¹

1965

Scandinavian Journal of Haematology

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The results are reported of a study on the E.S.F. (erythropoietic‐stimulating‐factor) in serum from 47 patients with leucosis and 11 patients with other haematological disorders, and a survey is given of previous studies of the same nature The analyses were performed over a period of 2 years Fe59 incorporation in the erythrocytes in starved rats was used as a criterion of the E.S.F. content in serum In patients with chronic lymphatic leucosis and acute leucosis, a reciprocal relationship was found between the E.S.F. titre and the haemoglobin percentage, and a similar reciprocal relationship was found between the E.S.F. titre and the bone marrow erythropoiesis. This must be interpreted to mean that there are other factors which determine these patients' defective erythropoiesis In patients with chronic myeloid leucosis, low values of E.S.F. were found in serum in spite of often reduced haemoglobin levels. Patients with high titres were observed, however, but in these cases the extramedullary erythropoiesis was inhibited, partly because of splenectomy, partly caused by roentgen treatment of the spleen. It seems reasonable to assume that the extramedullary, often ineffective splenic erythropoiesis requires E.S.F., and this might result in the low serum level and perhaps indirectly deprive the bone marrow of its natural stimulation

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Section: Eivind B Thorlingmentioning

confidence: 99%

Erythropoietin in Serum from Patients with Leucosis Assays in Starved Rats

Thorling¹

1965

Scandinavian Journal of Haematology

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Regulation of Erythropoietin Production

Fisher

1992

Comprehensive Physiology

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The sections in this article are: Physicochemical Properties of Erythropoietin Assay and Standardization of Erythropoietin Model for Kidney Production of Erythropoietin Renal Site of Production of Erythropoietin Extrarenal Erythropoietin Production Sites of Action of Erythropoietin Anemia of Renal Insufficiency Erythropoietin and Polycythemia Pharmacological Agents that Influence Erythropoietin Production Pharmacokinetics of Erythropoietin Potential Therapeutic uses of Erythropoietin Summary

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Polyglobulie und Polycythaemia vera

Stecher¹,

Reinhardt²

1970

Blut Und Blutkrankheiten

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Erythrocytosis and Hypernephroma

Cited by 13 publications

References 14 publications

Erythropoietin in Serum from Patients with Leucosis Assays in Starved Rats

Erythropoietin in Serum from Patients with Leucosis Assays in Starved Rats

Regulation of Erythropoietin Production

Polyglobulie und Polycythaemia vera

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