Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage

Adão, Diego; Góis, Aécio Flávio Teixeira de; Pacheco, Rafael Leite; Pimentel, Carolina Frade Magalhães Girardin; Riera, Rachel

doi:10.1002/14651858.cd013176.pub2

Cited by 6 publications

(2 citation statements)

References 71 publications

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“…5 Corresponding images of gastric fundus shown in primary (left lateral decubitus) and secondary (left lateral semi-recumbent) position with successful endotherapy done in the secondary position. need for second look endoscopy, and shorter hospital stay but without any benefit in blood transfusion requirement, endoscopy duration, or for emergency surgery [8,9]. In our hospital, erythromycin is not given routinely due to unavailability and adverse effects.…”

Section: Discussionmentioning

confidence: 98%

“…Prokinetics such as erythromycin and metoclopramide have shown to increase gastric emptying and improve visualization in acute upper gastrointestinal bleeding. Erythromycin use has been associated with adequate visualization, less need for second look endoscopy, and shorter hospital stay but without any benefit in blood transfusion requirement, endoscopy duration, or need for emergency surgery 8 9 . In our hospital, erythromycin is not given routinely due to unavailability and adverse effects.…”

Section: Discussionmentioning

confidence: 99%

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Utility of gastroscopy in the left lateral semi-recumbent position: A blood-free coup!

Patra,

Harindranath,

Ansari

et al. 2023

Endosc Int Open

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Background and study aims The utility of esophagogastroduodenoscopy (EGD) in the left lateral semi-recumbent position in the setting of acute upper gastrointestinal bleeding (UGIB) with a persistent fundal pool of blood for adequate visualization and effective endotherapy has not been studied. This study aimed to evaluate the feasibility, efficacy, and safety of this position in such settings. Patients and methods A prospective study of patients presenting with acute UGIB with an uncleared fundal pool of blood was conducted. All underwent EGD in the left lateral decubitus and secondary left lateral semi-recumbent positions. Outcomes in secondary position in terms of adequate visualization of the fundus, identification of new or additional sources of bleeding, and effectiveness of endotherapy were studied. Results We screened 860 patients and included 44 patients (5.11%) with a persistent fundal pool of blood. Endoscopy in the primary position revealed the source of bleeding in 37 of 44 patients (84%). The source of the bleeding was not identified in seven of 44 patients (16%). Endoscopy in the secondary position showed clearance of fundal pool in all 44 patients (100%). A new source of bleeding was identified in all seven patients (100%) and an additional source could be identified in another five patients (13.6%). Endotherapy was performed in the secondary position for all 44 patients with 100% technical success and 94% clinical success. Conclusions These data show that endotherapy in the left lateral semi-recumbent position is feasible, safe, and effective. It should be done when endoscopy in the left lateral decubitus position reveals a pool of blood in the fundus and there is inadequate visualization of the fundus.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%