Escitalopram oxalate (Lexapro)-induced acneiform eruption

Khanna, Sarika; Chirinos, Rodolfo E.; Venna, Suraj

doi:10.1016/j.jaad.2012.03.032

Cited by 9 publications

(3 citation statements)

References 5 publications

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“…Dermatologic side effects due to vortioxetine are redness of the face, neck, arms, and occasionally, upper chest, red or purple spots on the skin, itching skin [10]. No published reports have been found about vortioxetine in the English publications; however, case reports of escitalopram [11], sertraline [12], and duloxetine [13] are present.…”

Section: Discussionmentioning

confidence: 99%

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Acneiform eruption associated with the use of vortioxetine

Aytaş

2018

Psychiatry and Clinical Psychopharmacology

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Acneiform is used to describe eruptions that resemble acne vulgaris, but are not aetiologically similar. A number of drugs that can be responsible for acneiform eruptions exist. Vortioxetine is a multimodal antidepressant molecule that shows an antagonistic effect to the 5HT1D, 5HT3, and 5HT7 receptors, a partial agonistic effect to the 5HT1B receptor and a fully agonistic effect to the 5HT1A receptor, and also is an inhibitor to the serotonin transporter (SERT). In this article, we report a female patient who developed acneiform eruption during vortioxetine treatment.

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Section: Discussionmentioning

confidence: 99%

“…A 32-year-old woman, diagnosed with depression, developed pustular eruptions starting at the abdomen and spread to the arms and legs, 2 weeks after escitalopram use and the lesions decreased within weeks after medication was discontinued and without additional treatment needed [11].…”

Section: Discussionmentioning

confidence: 99%

Acneiform eruption associated with the use of vortioxetine

Aytaş

2018

Psychiatry and Clinical Psychopharmacology

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“…4 Several drugs have been associated with the development of acneiform eruptions including corticosteroids, anticonvulsants, antipsychotics, antidepressants, lithium, antituberculosis drugs, and immunomodulating molecules. 6 Acne may be related to sertralineinduced high activity in the serotonergic system at the dermal and epidermo-dermal junctional area. 6 Acne may be related to sertralineinduced high activity in the serotonergic system at the dermal and epidermo-dermal junctional area.…”

Section: Discussionmentioning

confidence: 99%