Esophageal carcinoma: initial results of palliative treatment with covered self-expanding endoprostheses.

Abstract

The insertion of plastic-covered endoprostheses provides rapid, safe, and effective palliation of malignant esophageal obstruction.

Stenting in Esophageal Strictures

“…This is most likely due to reduced friction between the membrane and the esophageal wall [30]. In the prospective randomized trial of expandable metal stents in the palliation of malignant esophageal obstruction at the gastroesophageal junction recently performed by Vakil et al [82], there was no significant difference in the incidence of stent migration (2/30 with uncovered stents as compared with 4/32 with covered stents; p = 0.44).…”

“…Stent insertion is a straightforward procedure associated with a negligible mortality and a low morbidity, and, in most patients, it rarely needs to be repeated. Moreover, placement of a metal stent across a tight stricture produces a virtually immediate and substantial improvement in swallowing [30][31][32].…”

In Vivo Evaluation of 5-Fluorouracil-Containing Self-Expandable Nitinol Stent in Rabbits: Efficiency in Long-Term Local Drug Delivery

“…[4][5][6] However, the failure of this endoluminal stent frequently occurred resulting from ingrowth and overgrowth of the device by tumor cells. [7][8][9][10][11] The overgrowth and ingrowth may result in restenosis and shortening the effective lifespan of the treatment. Moreover, with this palliative treatment, long-term survival cannot be expected, because proliferation and growth of malignant cells cannot be inhibited.…”

Antimigration property of a newly designed covered metal stent for esophageal stricture: an in vivo animal study

“…Overall migration rates of covered stents have been reported to be 5% to 32%, 3,[7][8][9][10][11] and migrated stents may induce serious problems such as luminal obstruction or perforation of the bowel. 12 Recently, we designed a novel, fully covered SEMS that resists migration (Hanarostent Skidpoof; M.I. Tech Co Ltd, Pyeongtaek, Korea).…”