Esophageal granular cell tumor colliding with intramucosal adenocarcinoma: a case report

Abstract

We report a case of a granular cell tumor colliding with intramucosal adenocarcinoma of the esophagus. A 58-year-old white was found to have a 5 mm nodule in the distal esophagus detected by upper gastrointestinal endoscopy performed as part of the workup of long standing reflux. Endoscopic biopsies revealed intramucosal adenocarcinoma arising in the setting of Barrett’s esophagus. The adenocarcinoma infiltrated a granular cell tumor also present at the nodular site. Endoscopic mucosal resection using Duette band ligation and hot snare electrocautery was performed. Margins were negative for both tumors, and endoscopic surveillance for recurrence is planned.

A Collision Tumor Consisting of Granular Cell Tumor and Adenocarcinoma in the Uterus of an Aged Djungarian Hamster

“…The present case of collision of a malignant adenocarcinoma and a benign granular cell tumor may be unique. In humans, the coexistence of granular cells as a part of tumors has been reported in three cases including ductal carcinomas of the breast 5 , intramuscular adenocarcinoma of the esophagus 22 and adenocarcinoma-malignant lymphoma composite of the stomach 23 . To our knowledge, there has been no report in animals of a collision or composite tumor including granular cells as one of the elements of the tumor tissues.…”

Esophageal Granular Cell Tumor and Eosinophils: A Multicenter Experience

“…There are reports of concomitant presentation of eGCT and other neoplasms, both benign and malignant, including leiomyoma, squamous cell carcinoma and intramucosal adenocarcinoma in the setting of Barrett esophagus [18][19][20]. The latter illuminates one of the more interesting and novel ndings of our study: the presence of eGCT in patients with an established diagnosis of Barrett esophagus or histologic evidence of goblet cell metaplasia having eGCT.…”

Successful transendoscopic oesophageal mass ablation in two dogs with Spirocerca lupi associated oesophageal sarcoma

“…, Alkhoury et al . ). Only two cases of mass removal using snares are published in veterinary medicine, one describing tracheal carcinoma cold snare debulking in two cats (Queen et al .…”

“…Food and water were withheld for 12 hours following the procedure. Two days following surgery the dog was discharged with 15 mg/kg amoxicillin-clavulanate, Transendoscopic oesophageal mass ablation including oesophageal masses (Alobid et al 2007, Liu et al 2008, Alkhoury et al 2009). Only two cases of mass removal using snares are published in veterinary medicine, one describing tracheal carcinoma cold snare debulking in two cats (Queen et al 2010), and the other an endometrial cyst removal in a mare (Rambags and Stout 2005).…”