Esophageal ulcers caused by reactivation of ganglionary tuberculosis: a case report

Hadlich, Everton; Galperim, Bruno; Rizzon, Carlos Fernando Carvalho

doi:10.1590/s1413-86702007000200026

Cited by 6 publications

(4 citation statements)

References 9 publications

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“…There are cases where treatment was successfully carried out with only three drugs for six months, excluding ethambutol [12,13]. Surgical treatment is reserved for complications such as esophageal, tracheoesophageal and aortoesophageal fistulas, the latter of which can lead to death by massive hematemesis [14].…”

Section: Discussionmentioning

confidence: 99%

Dysphagia as a manifestation of esophageal tuberculosis: a report of two cases

et al. 2011

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IntroductionEsophageal involvement by Mycobacterium tuberculosis is rare and the diagnosis is frequently made by means of an esophageal biopsy during the evaluation of dysphagia. There are few cases reported in the literature.Case presentationWe present two cases of esophageal tuberculosis in 85- and 65-year-old male Caucasian patients with initial complaints of dysphagia and epigastric pain. Upper gastrointestinal endoscopy resulted in the diagnosis of esophageal tuberculosis following the biopsy of lesions of irregular mucosa in one case and a sessile polyp in the other. Pulmonary tuberculosis was detected in one patient. In one patient esophageal stricture developed as a complication. Antituberculous therapy was curative in both patients.ConclusionAlthough rare, esophageal tuberculosis has to be kept in mind in the differential diagnosis of dysphagia. Pulmonary involvement has important implications for contact screening.

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Section: Discussionmentioning

confidence: 99%

Dysphagia as a manifestation of esophageal tuberculosis: a report of two cases

et al. 2011

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“…These drugs can also be used for treatment if the patient is intolerant toward the first-line agents. Though these drugs are currently approved by the FDA for treatment of TB, it is commonly used to treat the same [11][12][13][14].…”

Section: Discussionmentioning

confidence: 99%

A Rare Cause of Esophageal Dysphagia – Secondary Esophageal Tuberculosis

Baleguli¹,

Rizvi²,

Varghese³

et al. 2022

Cureus

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Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. It continues to be one of the most common causes of death in adults across all countries. It is found to be relatively lower in North America. When aerosol droplets that contain Mycobacterium tuberculosis are inhaled, it can deposit in the respiratory tract, particularly in the patient's lungs. Following this deposition, one of the four outcomes can take place. These include clearance of the organism immediately, primary disease, latent infection, and reactivation disease. Unhindered bacterial growth after primary infection can lead to a hematogenous spread of bacilli to produce disseminated TB. Esophageal involvement causing esophageal TB can be primary or secondary esophageal TB.We present a unique case of secondary esophageal TB with symptoms of dysphagia and odynophagia with primary TB focus on the lung. Computed tomography (CT) of the chest noted diffuse bilateral miliary lung disease. TB QuantiFERON gold and sputum culture were positive for TB. Mycobacterial culture for identification with high-performance liquid chromatography showed isoniazid-resistant TB. The patient was started on antitubercular therapy with rifampin, ethambutol, moxifloxacin, and pyrazinamide for a total of nine months. Esophagogastroduodenoscopy (EGD) reported severe ulcerations of the oropharynx and focal ulceration in the proximal to the mid esophagus. Histopathology revealed active ulcerative and granulomatous esophagitis with mycobacterial organisms. After EGD she was started on a full liquid diet and advanced as tolerated. After discharge, she followed with the Health Department and had three negative sputum cultures after the completion of therapy.

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“…Esophageal tuberculosis treatment is based on chemotherapy with four drugs (isoniazid, rifampicin, pyrazinamide and ethambutol) in a first phase lasting for two months, followed by a period of four to six months with two drugs (isoniazid and rifampicin). There are cases where treatment was successfully carried out with only three drugs for six months, excluding ethambutol [8], [9]. The two most common differential diagnoses are carcinoma of esophagus and Crohn’s disease of the esophagus [6], [7].…”

Section: Discussionmentioning

confidence: 99%