Esporotricosis fija con cuerpo asteroide junto al fragmento vegetal

Orellana, Álvaro; Moreno‐Coutiño, Gabriela; Poletti, Eduardo David; Vega, Maria Elisa; Arenas, Roberto

doi:10.1016/j.riam.2009.07.001

Cited by 3 publications

(3 citation statements)

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“…Cutaneous infections may also exhibit hyperkeratosis, parakeratosis, and pseudoepitheliomatous hyperplasia (130). Foreign bodies of vegetal origin related to the traumatic inoculation of the agent may also be encountered (182).…”

Section: Histopathological Examinationmentioning

confidence: 99%

Sporothrix schenckii and Sporotrichosis

Barros

Paes²,

Schubach³

2011

Clin Microbiol Rev

531

677

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SUMMARY Sporotrichosis, which is caused by the dimorphic fungus Sporothrix schenckii , is currently distributed throughout the world, especially in tropical and subtropical zones. Infection generally occurs by traumatic inoculation of soil, plants, and organic matter contaminated with the fungus. Certain leisure and occupational activities, such as floriculture, agriculture, mining, and wood exploitation, are traditionally associated with the mycosis. Zoonotic transmission has been described in isolated cases or in small outbreaks. Since the end of the 1990s there has been an epidemic of sporotrichosis associated with transmission by cats in Rio de Janeiro, Brazil. More than 2,000 human cases and 3,000 animal cases have been reported. In humans, the lesions are usually restricted to the skin, subcutaneous cellular tissue, and adjacent lymphatic vessels. In cats, the disease can evolve with severe clinical manifestations and frequent systemic involvement. The gold standard for sporotrichosis diagnosis is culture. However, serological, histopathological, and molecular approaches have been recently adopted as auxiliary tools for the diagnosis of this mycotic infection. The first-choice treatment for both humans and cats is itraconazole.

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Section: Histopathological Examinationmentioning

confidence: 99%

Sporothrix schenckii and Sporotrichosis

Barros

Paes²,

Schubach³

2011

Clin Microbiol Rev

531

677

View full text Add to dashboard Cite

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“…Sporotrichosis has been classified into four clinical categories: (a) fixed cutaneous, (b) lymphocutaneous, (c) multifocal, and (d) extracutaneous (systemic or visceral). It has a bad prognosis as it is associated with immunosuppression [ 24 , 25 , 26 , 28 , 29 , 30 , 31 ]. Figure 2 illustrates two of the most common clinical lesions of sporotrichosis.…”

Section: Sporothrix and Sporotrichosismentioning

confidence: 99%

Fungal Glycosidases in Sporothrix Species and Candida albicans

Ortiz-Ramírez,

Cuéllar-Cruz,

Villagómez-Castro

et al. 2023

JoF

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Glycoside hydrolases (GHs) are enzymes that participate in many biological processes of fungi and other organisms by hydrolyzing glycosidic linkages in glycosides. They play fundamental roles in the degradation of carbohydrates and the assembly of glycoproteins and are important subjects of studies in molecular biology and biochemistry. Based on amino acid sequence similarities and 3-dimensional structures in the carbohydrate-active enzyme (CAZy), they have been classified in 171 families. Members of some of these families also exhibit the activity of trans-glycosydase or glycosyl transferase (GT), i.e., they create a new glycosidic bond in a substrate instead of breaking it. Fungal glycosidases are important for virulence by aiding tissue adhesion and colonization, nutrition, immune evasion, biofilm formation, toxin release, and antibiotic resistance. Here, we review fungal glycosidases with a particular emphasis on Sporothrix species and C. albicans, two well-recognized human pathogens. Covered issues include a brief account of Sporothrix, sporotrichosis, the different types of glycosidases, their substrates, and mechanism of action, recent advances in their identification and characterization, their potential biotechnological applications, and the limitations and challenges of their study given the rather poor available information.

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“…In addition to intact polymorphonuclear cells, the granuloma formed during sporotrichosis may also contain cellular debris, caseous material, lymphocytes, plasmocytes, giant and epithelioid cells, fibroblasts and yeasts (Quintella et al, 2011). Some authors also report that foreign material of vegetal origin related to the traumatic inoculation of the agent may be found in rare cases (Orellana et al, 2009). Some histopathologic changes on analysed tissues may be also related to the observation of the etiologic agent on tissue sections.…”

Section: Conventional Diagnosismentioning

confidence: 99%