Essential and fatty oils of Agastache rugosa

Zakharov, A.M.; Dolya, V. S.; Захарова, О. И.; Беспалова, Array А.; Литвинова, Н. В.

doi:10.1007/bf00598595

Cited by 4 publications

(4 citation statements)

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“…The polyphenols were characterized by their molecular ion peaks and MS/MS fragmentation patterns, in comparison with previously published data. Out of the 12 previously reported polyphenols (Zakharova et al ., ; Itokawa et al ., ; Vogelmann, ; Zakharov et al ., ; Oh et al ., ; Tuan et al ., ; Zielińska and Matkowski, ), only three rosmarinic acid derivatives and apigenin ( 6–8 and 13 ) were found in the present A . rugosa extracts.…”

Section: Resultsmentioning

confidence: 97%

“…Twelve polyphenolic components of A . rugosa were previously reported: tilianin, acacetin, linarin, agastachin, luteonin 7‐ O ‐glucoside, (iso)agastachoside, 5‐hydroxy‐4‐methoxy‐7‐ O ‐rhamnosylflavone, apigenin 7‐ O ‐glucoside, rosmarinic acid, apigenin, 4',5‐dihydroxy‐3,3′,7‐trimethoxyflavone and 3,4‐dihydroxyphenyllactic acid (Zakharova et al ., ; Itokawa et al ., ; Vogelmann, ; Zakharov et al ., ; Oh et al ., ; Tuan et al ., ; Zielińska and Matkowski, ). Only one polyphenol and rosmarinic acid have been reported previously using Korean A .…”

Section: Introductionmentioning

confidence: 97%

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The polyphenolic profiles and antioxidant effects of Agastache rugosa Kuntze (Banga) flower, leaf, stem and root

Desta

Kim

et al. 2015

Biomedical Chromatography

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Agastache rugosa Kuntze (Korean mint) is used as a spice and in folk medicine in East Asia. The present study identified a total of 18 polyphenols from the flower, leaf, stem and roots of this plant using high-performance liquid chromatography-tandem mass spectrometry. Fourteen of these compounds had not previously been identified in these plant tissues. Each polyphenol was validated in comparison with external calibration curves constructed using structurally related compounds, with determination coefficients >0.9993. The limits of detection and quantification were 0.092-0.650 and 0.307-2.167 mg/L, respectively. Recoveries of 61.92-116.44% were observed at two spiking levels, with 0.91-11% precision, expressed as relative standard deviation (except anthraquinone spiked at 10 mg/L). Hydroxycinnamic acid was the most abundant compound in the root, while the flowers showed the highest total flavonoid level. Antioxidant activities, determined in terms of reducing power, Fe(2+) chelating activity and the radical scavenging activities using α,α-diphenyl-β-picrylhydrazyl and 2-2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid, increased in a concentration-dependent manner; the highest activity was identified in the stems, followed by leaves > flowers > roots. These findings indicate that A. rugosa is a good source of bioactive compounds and can be used as a functional food.

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Section: Resultsmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 97%

The polyphenolic profiles and antioxidant effects of Agastache rugosa Kuntze (Banga) flower, leaf, stem and root

Desta

Kim

et al. 2015

Biomedical Chromatography

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“…The seed oil from A. rugosa studied for fatty acid composition consisted of 91 % unsaturated fatty acids, of which 52 % were C18:3 (linolenic acid), 27.5 % were C18:2 (linoleic acid) and 11.5 % were monounsaturated C18:1 (oleic acid) acids (Zakharov et al 1988 ).…”

Section: Phytochemistrymentioning

confidence: 99%

Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae)

2014

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Agastache is a small genus of Lamiaceae, comprising 22 species of perennial aromatic medicinal herbs. In this article, we review recent advances in phytochemical, pharmacological, biotechnological and molecular research on Agastache. The phytochemical profile of all Agastache species studied to date is generally similar, consisted of two main metabolic classes—phenylpropanoids and terpenoids. In the relatively variable essential oils, most populations of different Agastache species contain over 50 % of a phenylallyl compound—estragole. Also, other volatile compounds (methyleugenol, pulegone, menthone, isomenthone and spathulenol) were reported in various proportions. Major non-volatile metabolites belong to phenolic compounds, such as caffeic acid derivatives, especially rosmarinic acid as well as several flavones and flavone glycosides like acacetin, tilianin, agastachoside, and a rare dimeric malonyl flavone (agastachin). Two unique lignans—agastenol and agastinol—were also isolated. Terpenoids include triterpenoids of oleanane-type (maslinic acid, oleanolic acid and β-amyrin), ursane-type (ursolic acid, corosolic acid and α-amyrin), and typical plant sterols, as well as abietane-type oxidized diterpenes (e.g., agastaquinone, agastol, and others). The bioactivity of various extracts or individual compounds in vitro and in vivo include antimicrobial, antiviral and anti-mutagenic activity, cytotoxic activity to cancer cell lines, and anti-nociceptive, anti-inflammatory, anti-atherogenic, antioxidant as well as biocidal activity to several foodstuff pests. Biotechnological and molecular studies have focused on in vitro propagation and enhancing the biosynthesis of bioactive metabolites in cell or organ cultures, as well as on the expression of genes involved in phenolic biosynthesis.

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“…84-92 % methyl eugenol and only 2-6 % estragole 12 . Chemotypes of the essential oil components in individual A. rugosa samples collected from Scotland and the USA have been analyzed [13][14][15] , but those in the case of Korean A. rugosa samples have not been analyzed in detail. The essential oil contents of the leaves and inflorescences of Korean A. rugosa are 0.29 and 0.38 % (in dry weight), respectively, with estragole constituting ca.…”

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confidence: 99%

Chemical Composition of Essential Oils from Flower and Leaf of Korean Mint, Agastache rugosa

Lim¹,

Jang²,

Park³

et al. 2013

Asian J. Chem.

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Korean mint, Agastache rugosa Kuntze belongs to the family Labiatae, is a perennial herb widely distributed in East and Southeast Asian countries. Agastache rugosa has been used in Chinese traditional medicine for the treatment of cholera, emesis and miasma and has been reported to have antitumor, antifungal, HIV integrase inhibitory and cytotoxic activities 1-7. In addition, the leaves and flowers of A. rugosa are used as spices in fish-based foods and as a source of honey, respectively 8. Estragole (p-allylanisole, methyl chavicol), a component of the essential oil extracted from A. rugosa, is used as a sweet condiment as well as in perfumes and salad dressings. Moreover, estragole is an important constituent of root beer and can be used to prepare other flavoring agents such as anethole and anisaldehyde. In Korea, the essential oil from A. rugosa has traditionally been used for medicinal purposes 8. In addition, estragole is a major component (56-94 %) of the leaf of natural populations of A. rugosa grown in Ames, Iowa 9,10 and Ishikawa, Hyogo Prefecture, Japan 11,12. In contrast, a population of A. rugosa (A. rugosa O. Kuntze var. methyleugenolifera) collected from Kitami, Hokkaido, Japan, has been found to contain

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Essential and fatty oils of Agastache rugosa

Cited by 4 publications

References 2 publications

The polyphenolic profiles and antioxidant effects of Agastache rugosa Kuntze (Banga) flower, leaf, stem and root

The polyphenolic profiles and antioxidant effects of Agastache rugosa Kuntze (Banga) flower, leaf, stem and root

Phytochemistry and bioactivity of aromatic and medicinal plants from the genus Agastache (Lamiaceae)

Chemical Composition of Essential Oils from Flower and Leaf of Korean Mint, Agastache rugosa

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