Essential and xenobiotic elements in cottage cheese from the Slovak market with a consumer risk assessment

Capcarová, Marcela; Harangozo, Ľuboš; Árvay, Július; Tóth, Tomáš; Gabríny, Lucia; Binkowski, Łukasz J.; Palšová, Lucia; Skalická, M.; Garcia, María de la Luz; Stawarz, Robert; Massányi, Peter

doi:10.1080/03601234.2020.1762420

Cited by 12 publications

(15 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study revealed ivermectin-treated animal demonstrated necrosis in the endometrial lining, coupled with degenerated luminal epithelium. Cadmium administration promotes abnormal follicular growth, cell death, follicular damage, and tumours [68][69][70][71]. These reports have been in agreement with the result obtained in this study; atretic follicules, arrest of follicular development, and degeneration of ovarian cortex were reported in this study in line with the reports of Golubnitschaja et.…”

Section: Discussionsupporting

confidence: 93%

Ivermectin and Allium cepa Protect against Cadmium-Induced Ovarian and Uterine Damage in Adult Wistar Rats

Dare

2022

PAJOLS

View full text Add to dashboard Cite

Background: Female reproductive organs are more susceptible to the risk of increased cadmium accumulation. Ivermectin is a known therapeutic drug in general medicine, while Allium cepa possesses antioxidant ability. This study investigated the effects of Ivermectin and Allium cepa on cadmium-induced ovarian and uterine damage in adult Wistar rats. Methodology: Twenty-Eight adult female Wistar rats were randomly divided into six groups. Group (A); control group, Group (B); treated with 1.2 mg/kg b.w of Ivermectin, Group (C); treated with 1.2 mg/kg BW of Ivermectin and 2 mg/kg BW Cadmium respectively, Group (D); treated with 2 mg/kg BW Cadmium, Group (E); treated with 2 mg/kg BW Cadmium and 1.5 ml Allium cepa respectively, and Group (F); treated with 1.5 ml Allium cepa. The administration was done orogastrically and daily for four weeks. Animals were euthanized by cervical dislocation twenty- four hours after the last administration, Ovary and Uterus excised following abdominal incision, tissues for histological observation fixed in Bouins’ fluid for H/E stain, Masson trichrome, fuelgen stain, and toluidine blue stain respectively. Samples for enzymes assay were homogenized in 5% sucrose solution for lipid peroxidation using; MDA and the antioxidant enzymes using SOD and CAT. Result: Cadmium treatment exerted oxidative stress, elevated the enzyme markers for oxidative damage in the ovary and uterus, and increased lipid peroxidation leading to cell membrane damage. Histological alterations, degeneration of ovarian follicles, and loss of endometrial lining characterized the animals exposed to cadmium. Allium cepa increased the antioxidant enzymes; SOD and CAT while lowering the MDA activities in Cadmium-induced oxidative stress. Histological integrity of the ovary and uterus was maintained; follicular development was evident at various stages, and the endometrial lining integrity was maintained. Conclusion: This study demonstrated the protective role of Allium cepa and Ivermectin against cadmium toxicity on the reproductive organs in female adult Wistar rats

show abstract

Section: Discussionsupporting

confidence: 93%

Ivermectin and Allium cepa Protect against Cadmium-Induced Ovarian and Uterine Damage in Adult Wistar Rats

Dare

2022

PAJOLS

View full text Add to dashboard Cite

show abstract

“…Closer to our data, Ünal et al (2005) established a wide range of Ca levels, between 183.5-651.0 mg/100 g, in five different varieties of Turkish cheese. Concerning Mg, mean concentrations detected in this trial were within values previously documented in processed cheese (19.9 mg/100 g) (Cruijsen et al, 2019); in Dutch and Swiss-type cheese (33.0 mg/100 g) (Aljewicz and Cichosz, 2015); and below levels of several cottage cheeses from the Slovak market (5.8-8.4 mg/100 g) (Capcarova et al, 2020).…”

Section: Chemical Characterization Of Cheese: Nutrient Composition An...supporting

confidence: 79%

“…Since milk is not considered a good dietary source of Zn, few investigations report Zn concentration in cheese. The former study by Capcarova et al (2020) detected low Zn values of 0.18− 0.23 mg/100 g. The higher moisture content of the cottage cheese compared with the short-ripened cheeses of the present assay could partially explain the high differences in the Zn and Mg content. On their part, Herman-Lara (2015) detected Zn concentrations of 3.6-4.1 mg/100 g in their study.…”

Section: Chemical Characterization Of Cheese: Nutrient Composition An...contrasting

confidence: 44%

Bioavailability evaluation of calcium, magnesium and zinc in Brazilian cheese through a combined model of in vitro digestion and Caco-2 cells

Teixeira

Pallone

Delgado-Andrade

et al. 2022

Journal of Food Composition and Analysis

View full text Add to dashboard Cite

“…Third, the cumulative effect of environmental factors may play a crucial role in advanced maternal age's effect on spontaneous abortion ( 56 ). Previous studies found correlations between ambient air pollutant levels ( 57 ), exposure to Bisphenol A ( 58 ), and exposure to heavy metals such as cadmium, lead, and mercury ( 59 ) and spontaneous abortion.…”

Section: Discussionmentioning

confidence: 99%

Non-linear Relationship of Maternal Age With Risk of Spontaneous Abortion: A Case-Control Study in the China Birth Cohort

Zhang

Yang

Sun

et al. 2022

Front. Public Health

View full text Add to dashboard Cite

BackgroundSpontaneous abortion is one of the prevalent adverse reproductive outcomes, which seriously threatens maternal health around the world.ObjectiveThe current study is aimed to evaluate the association between maternal age and risk for spontaneous abortion among pregnant women in China.MethodsThis was a case-control study based on the China Birth Cohort, we compared 338 cases ending in spontaneous abortion with 1,352 controls resulting in normal live births. The main exposure indicator and outcome indicator were maternal age and spontaneous abortion, respectively. We used both a generalized additive model and a two-piece-wise linear model to determine the association. We further performed stratified analyses to test the robustness of the association between maternal age and spontaneous abortion in different subgroups.ResultsWe observed a J-shaped relationship between maternal age and spontaneous abortion risk, after adjusting for multiple covariates. Further, we found that the optimal threshold age was 29.68 years old. The adjusted odds ratio (95% confidence interval) of spontaneous abortion per 1 year increase in maternal age were 0.97 (0.90–1.06) on the left side of the turning point and 1.25 (1.28–1.31) on the right side. Additionally, none of the covariates studied modified the association between maternal age and spontaneous abortion (P > 0.05).ConclusionsAdvanced maternal age (>30 years old) was significantly associated with increased prevalence of spontaneous abortion, supporting a J-shaped association between maternal age and spontaneous abortion.

show abstract

Essential and xenobiotic elements in cottage cheese from the Slovak market with a consumer risk assessment

Cited by 12 publications

References 39 publications

Ivermectin and Allium cepa Protect against Cadmium-Induced Ovarian and Uterine Damage in Adult Wistar Rats

Ivermectin and Allium cepa Protect against Cadmium-Induced Ovarian and Uterine Damage in Adult Wistar Rats

Bioavailability evaluation of calcium, magnesium and zinc in Brazilian cheese through a combined model of in vitro digestion and Caco-2 cells

Non-linear Relationship of Maternal Age With Risk of Spontaneous Abortion: A Case-Control Study in the China Birth Cohort

Contact Info

Product

Resources

About