Essential Oil Constituents of<i>Piper vicosanum</i>Yunker from the Brazilian Atlantic Forest

Mesquita, Jussara; Oliveira, Alaı́de Braga de; Braga, Fernão Castro; Lombardi, Júlio Antônio; Cunha, A. Proença da; Salgueiro, Lígia; Cavaleiro, Carlos

doi:10.1080/10412905.2006.9699123

Cited by 6 publications

(5 citation statements)

References 29 publications

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“… Parque Estabdual do Rio Doce, Minas Gerais state, Brazil Aerial parts (HD) α-Pinene (6.1%), 1,8-cineole (10.4%), limonene (45.5%) --- [ 153 ] P. vicosanum Yunck. Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais state, Brazil Aerial parts (HD) α-Pinene (7.2%), 1,8-cineole (15.0%), limonene (40.0%), terpinolene (10.1%) --- [ 153 ] P. vicosanum Yunck. Dourados, Mato Grosso do Sul, Brazil Leaf (HD) Limonene (9.1%), γ-elemene (14.2%), α-alaskene (13.4%) Anti-inflammatory (rat paw edema, 100–300 mg/kg) [ 89 ] P. vitaceum Yunck.…”

Section: Table A1mentioning

confidence: 99%

Essential Oils from Neotropical Piper Species and Their Biological Activities

Silva

et al. 2017

IJMS

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The Piper genus is the most representative of the Piperaceae reaching around 2000 species distributed in the pantropical region. In the Neotropics, its species are represented by herbs, shrubs, and lianas, which are used in traditional medicine to prepare teas and infusions. Its essential oils (EOs) present high yield and are chemically constituted by complex mixtures or the predominance of main volatile constituents. The chemical composition of Piper EOs displays interspecific or intraspecific variations, according to the site of collection or seasonality. The main volatile compounds identified in Piper EOs are monoterpenes hydrocarbons, oxygenated monoterpenoids, sesquiterpene hydrocarbons, oxygenated sesquiterpenoids and large amounts of phenylpropanoids. In this review, we are reporting the biological potential of Piper EOs from the Neotropical region. There are many reports of Piper EOs as antimicrobial agents (fungi and bacteria), antiprotozoal (Leishmania spp., Plasmodium spp., and Trypanosoma spp.), acetylcholinesterase inhibitor, antinociceptive, anti-inflammatory and cytotoxic activity against different tumor cells lines (breast, leukemia, melanoma, gastric, among others). These studies can contribute to the rational and economic exploration of Piper species, once they have been identified as potent natural and alternative sources to treat human diseases.

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Section: Table A1mentioning

confidence: 99%

Essential Oils from Neotropical Piper Species and Their Biological Activities

Silva

et al. 2017

IJMS

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“…The genus Piper (Piperaceae family) consists of more than 700 species distributed in tropical and subtropical regions in the world and is used mainly for spices and seasonings. Traditionally, this genus is employed to treat inflammation, skin irritation, bronchitis, and intestinal pains [8,9]. Some EOs from this genus for example P. gaudichaudianum , P. humaytanum , P. permucronatum , and P. hostmanianum exhibit larvicidal activity [10].…”

Section: Introductionmentioning

confidence: 99%

Biological Activities and Chemical Constituents of Essential Oils from Piper cubeba Bojer and Piper nigrum L.

et al. 2019

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In this study, we evaluated antioxidant, antihyperuricemic, and herbicidal activities of essential oils (EOs) from Piper cubeba Bojer and Piper nigrum L.; two pepper species widely distributed in tropics, and examined their chemical compositions. Dried berries of P. cubeba and P. nigrum were hydro-distilled to yield essential oil (EO) of 1.23 and 1.11% dry weight, respectively. In the antioxidant assay, the radical scavenging capacities of P. cubeba EO against DPPH and ABTS free radicals were 28.69 and 24.13% greater than P. nigrum, respectively. In the antihyperuricemic activity, P. cubeba EO also exhibited stronger inhibitory effects on xanthine oxidase (IC50 = 54.87 µg/mL) than P. nigrum EO (IC50 = 77.11 µg/mL). In the herbicidal activity, P. cubeba EO showed greater inhibition on germination and growth of Bidens pilosa and Echinochloa crus-galli than P. nigrum EO. Besides, P. cubeba EO decreased 15.98–73.00% of photosynthesis pigments of B. pilosa and E. crus-galli, while electrolyte leakages, lipid peroxidations, prolines, phenolics, and flavonoids contents were increased 10.82–80.82% at 1.93 mg/mL dose. Gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) analyses revealed that P. nigrum and P. cubeba EOs principally possessed complex mixtures of monoterpenes and sesquiterpenes. Terpinen-4-ol (42.41%), α-copaene (20.04%), and γ-elemene (17.68%) were the major components of P. cubeba EO, whereas β-caryophyllene (51.12%) and β-thujene (20.58%) were the dominant components of P. nigrum EO. Findings of this study suggest both P. cubeba and P. nigrum EOs were potential to treat antioxidative stress and antihyperuricemic related diseases. In addition, the EOs of the two plants may be useful to control B. pilosa and E. crus-galli, the two invasive and problematic weeds in agriculture practice.

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“…Essential volatile oils, characteristic of most species of this genus, have also been object of several studies, revealing valuable biological activities and interesting compositions with monoterpenoids, sesquiterpenoids and seldom phenyl-and arylpropanoids (Mesquita et al, 2006). According to Mesquita et al (2006), the composition of P. vicosanum leaves was dominated by monoterpenoids, with limonene and 1.8-cineole as major compounds. These data corroborate the results obtained in this study, in which the predominance of monoterpenoids (limonene) was identified in the OPV, in addition to sesquiterpenoids (Y-elemene and a-alaskene).…”

Section: Discussionmentioning

confidence: 99%

“…The genus Piper (Piperaceae family) comprises about 2000 species distributed in the tropical and subtropical regions. Piper species have been widely used in folk medicine for the treatment of various diseases such as bronchitis, intestinal pains, skin irritations and inflammation, and in the preparation of ceremonial drinks (Mesquita et al, 2006;Wang et al, 2014). Phytochemical analyses of this genus have demonstrated the occurrence of alkaloids, amides, propenylphenols, lignans, neolignans, steroids, pyrones, chalcones, dihydrochalcones, flavones and terpenoids (Sengupta and Ray, 1987;Parmar et al, 1997).…”

Section: Introductionmentioning

confidence: 99%

“…Piper vicosanum Yuncker is a shrub that occurs in the Brazilian Atlantic Forest. The study carried out by Mesquita et al (2006), revealed that this species possesses volatile oils with valuable biological activities, such as limonene (45.5%), a-pinene (6.1%), piperitone (3.4%), b-caryophyllene (1.4%), a-selinene (3.2%), Dcadinene (2.2%), spathulenol (0.3%), caryophyllene oxide (0.4%), bpinene (0.2%), linalool and germacrene D traces, demonstrating the need for further studies about this species. Thus, due to the lack of studies in the literature using the Piper species, this study evaluated the anti-inflammatory effects of the essential oil extracted from P. vicosanum leaves (OPV) and determined the toxicological potential of this oil through acute toxicity, genotoxicity and mutagenicity tests.…”

Section: Introductionmentioning

confidence: 99%

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Toxicological analysis and anti-inflammatory effects of essential oil from Piper vicosanum leaves

Brait

Vaz

Arrigo

et al. 2015

Regulatory Toxicology and Pharmacology

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This study assessed the anti-inflammatory effects of the essential oil from Piper vicosanum leaves (OPV) and evaluated the toxicological potential of this oil through acute toxicity, genotoxicity and mutagenicity tests. The acute toxicity of OPV was evaluated following oral administration to female rats at a single dose of 2 g/kg b.w. To evaluate the genotoxic and mutagenic potential, male mice were divided into five groups: I: negative control; II: positive control; III: 500 mg/kg of OPV; IV: 1000 mg/kg of OPV; V: 2000 mg/kg of OPV. The anti-inflammatory activity of OPV was evaluated in carrageenan-induced pleurisy and paw edema models in rats. No signs of acute toxicity were observed, indicating that the LD50 of this oil is greater than 2000 mg/kg. In the comet assay, OPV did not increase the frequency or rate of DNA damage in groups treated with any of the doses assessed compared to that in the negative control group. In the micronucleus test, the animals treated did not exhibit any cytotoxic or genotoxic changes in peripheral blood erythrocytes. OPV (100 and 300 mg/kg) significantly reduced edema formation and inhibited leukocyte migration analyzed in the carrageenan-induced edema and pleurisy models. These results show that OPV has anti-inflammatory potential without causing acute toxicity or genotoxicity.

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Essential Oil Constituents ofPiper vicosanumYunker from the Brazilian Atlantic Forest

Cited by 6 publications

References 29 publications

Essential Oils from Neotropical Piper Species and Their Biological Activities

Essential Oils from Neotropical Piper Species and Their Biological Activities

Biological Activities and Chemical Constituents of Essential Oils from Piper cubeba Bojer and Piper nigrum L.

Toxicological analysis and anti-inflammatory effects of essential oil from Piper vicosanum leaves

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