The chemical composition of Prangos scabra and component activities have been investigated by several authors [1][2][3][4][5][6]. The air-dried fruits and inflorescence of Prangos scabra yielded 1.6% and 0.3% of a pale yellow oil, respectively. In the DPPH assay, the essential oils of the fruits (EOF) and inflorescence (EOI) exhibited weak free radical scavenging activities with RC 50 values of 1.58 and 1.42 mg/mL, respectively.The identified compounds from these essential oils [7,8], their retention indices, amounts (%) are summarized in Table 1. In the present study, while 20 major components, 67.1% of which were sesquiterpenes and 23.3% oxygenated sesquiterpenes, were identified in the EOF, the EOI were found to contain 14 main components, among which 15% were sesquiterpenes and 45.3% were oxygenated sesquiterpenes.The two most abundant components of the EOF were identified as β-elemene (19.9%) and β-farnesene (16.2%), whereas the EOI consists of epi-globulol (21.1%) and β-elemene (19.7%) as the two major components. Among the oxygenated sesquiterpenes, epi-globulol, spathulenol, caryophyllenoxide, and α-cadinol were the main components. The EOF contained only a small amount of monoterpenes, β-pinene (0.1%) and D-limonene (0.3%), while no monoterpenes in the EOI were present in detectable amounts. It is interesting to note that β-pinene, D-limonene, germacrene D, valencene, α-bisabolol, γ-cadinene, germacrene B, elemol, p-cresol, and α-bisabolol were present in the EOF but not in the EOI. Similarly, β-selinene, calarene, and p-methoxyacetophenone were found in the EOI but not in the EOF (Table 1).A comparison of the essential oil composition of Prangos scabra with that of some other members of the genus Prangos, available in the literature [4,6,[9][10][11][12][13][14][15][16][17][18][19], shows that considerable variations exist in the compositions of the essential oils of different species of the genus Prangos, especially in terms of the type of major components present. It has been found that the most abundant component in the essential oils of P. uloptera [6,9,10,12], P. asperula subsp. haussknechth [11], P. bornmuelleri [15], P. heyniae [13], P. ferulaveae [18], and P. uechtritzii [13] were, respectively, α-pinene (15.0%), ∆ 3 -carene (16.1%), germacrene D (42%), β-bisabolene (53.3%), γ-terpinene (27.8%), and p-cymene (10.9%), whereas β-elemene was the main component of P. scabra. However, α-and β-pinene, germacrene D, and germacrene B are of common occurrence in the essential oils of fruits of nearly all investigated Prangos species.
ACKNOWLEDGMENT