Essential Oils and Methylglyoxal: A Possible Alternative Treatment for Antibiotic Resistant Bacterial Infections

Abstract

<p><strong>Objective: </strong>Essential oils are of significant interest in today’s world of healthcare because these compounds have a variety of medicinal properties. In this study, we evaluated the <em>in vitro</em> antibiotic role of essential oils as a possible alternative treatment in combatting Methicillin-resistant <em>Staphylococcus aureus</em> (MRSA).</p><p><strong>Methods: </strong>In conjunction with carrier oils, three essential oils (cassia, cinnamon bark, and thyme), as well as methylglyoxal were tested on MRSA using the Kirby-Bauer disc diffusion method.</p><p><strong>Results: </strong>The minimum inhibitory concentration of each tested essential oil and methylglyoxal in carrier oil was determined to be 25% essential oil and 75% carrier oil mixture. This concentration worked much more effectively than the standard antibiotic, vancomycin, which is currently used to treat MRSA infections.</p><p><strong>Conclusion: </strong>Antibacterial emollients made from naturally occurring products like essential oils can be cost-effective alternatives to antibiotics. The results of this research show that these emollients are more effective against MRSA than standard antibiotics in cell culture.</p>

Chemical composition and antibacterial activity of essential oils against pathogens often related to cattle endometritis

“…Our results of IZD of cinnamon essential oil against E. coli (32 mm) are similar to those described by Nimje et al [31] (32 mm), Melo et al [32] (30 mm) and Zhu et al [34] (30 mm), and larger than those described by Zhang et al [19] (19 mm). Based on the results observed in the present study the IZD (38 mm) of cinnamon essential oil against S. aureus, our results are in agreement with those described by Melo et al [32] (40 mm) and Cieslak et al [33] (35 mm), and larger than those described by Zhu et al [34] (29 mm), Zhang et al [19] (28 mm) and Nimje et al [31] (21 mm). The main component of Cinnamon cassia oil used in this study was cinnamaldehyde (86%).…”

“…Several authors have reported the antibacterial activity of Cinnamon cassia essential oil [19,[31][32][33][34]. Our results of IZD of cinnamon essential oil against E. coli (32 mm) are similar to those described by Nimje et al [31] (32 mm), Melo et al [32] (30 mm) and Zhu et al [34] (30 mm), and larger than those described by Zhang et al [19] (19 mm).…”