Complex optimal design and control processes often require repeated evaluations of expensive objective functions and consist of large design spaces. Data-driven surrogate models such as neural networks and Gaussian processes provide an attractive alternative to expensive simulations and are utilized frequently to represent these objective functions in optimization. However, pure data-driven models, due to a lack of adherence to basic physics laws and constraints, are often poor at generalizing and extrapolating. This is particularly the case, when training occurs over sparse high-fidelity datasets. A class of Physicsinfused machine learning (PIML) models integrate ML models with low-fidelity partial physics models to improve generalization performance while retaining computational efficiency. This paper presents two potential approaches for Physics infused modelling of aircraft aerodynamics which incorporate Artificial Neural Networks with a low-fidelity Vortex Lattice Method model with blown wing effects (BLOFI) to improve prediction performance while also keeping the computational cost tractable. This paper also develops an end-to-end auto differentiable open-source framework that enables efficient training of such hybrid models. These two PIML modelling approaches are then used to predict the aerodynamic coefficients of a 6 rotor eVTOL aircraft given its control parameters and flight conditions. The models are trained on a sparse high-fidelity dataset generated using a CHARM model. The trained models are then compared against the vanilla low-fidelity model and a standard pure data-driven ANN. Our results show that one of the proposed architecture outperforms all the other models and at a nominal increase in execution time. These results are promising and pave way to PIML frameworks which are able generalize over different aircraft and configurations thereby significantly reducing costs of design and control.