Establishment of a Pediatric Liver Transplantation Program: Experience With 100 Transplantation Procedures

Ciria, Rubén; Sánchez-Hidalgo, Juan Manuel; Briceño, Javier; Naranjo, Álvaro; Pleguezuelo, M.; Díaz-Nieto, Rafael; Luque, A.; Jiménez, José Luís; García-Menor, Emilia; Gilbert, Juan J.; Mata, Manuel de la; Pérez-Navero, Juan Luís; Solórzano, G; Rufián, Sebastián; Pera, C; López‐Cillero, Pedro

doi:10.1016/j.transproceed.2009.06.072

Cited by 6 publications

(3 citation statements)

References 5 publications

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“…The majority (63%) of liver donors were cadaveric and almost half were reduced size. The use of a living donor (12%) became more common in the last two decades ( Table 1 ) as shown by others [ 13 ]. In 22 years of OLT in children 27% took place in infants (<12 months of age) and less than 1% in neonates (<2 month).…”

Section: Discussionmentioning

confidence: 82%

Early Critical Care Course in Children after Liver Transplant

Kukreti

Daoud

Bola

et al. 2014

Critical Care Research and Practice

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Objective. To review the critical care course of children receiving orthotopic liver transplantation (OLT). Methods. A retrospective chart review of patients admitted to the pediatric critical care following OLT performed in our center between 1988 and 2011. Results. A total of 149 transplants in 145 patients with a median age of 2.7 (IQR 0.9–7) years were analyzed. Mortality in the first 28 days was 8%. The median length of stay (LOS) was 7 (4.0–12.0) days. The median length of mechanical ventilation (MV) was 3 (1.0–6.2) days. Open abdomen, age, and oxygenation index on the 2nd day predicted LOS. Open abdomen, age, amount of blood transfused during surgery, and PRISM III predicted length of MV. 28% of patients had infection and 24% developed acute rejection. In recent group (2000–2011) OLT was performed in younger patients; the risk of infection and acute rejection was reduced and patients required longer LOS and MV compared with old group (1988–1999). Conclusion. The postoperative course of children after OLT is associated with multiple complications. In recent years OLT was performed in younger children; living donors were more common; the rate of postoperative infection and suspected rejection was reduced significantly; however patients required longer MV and LOS in the PCCU.

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Section: Discussionmentioning

confidence: 82%

Early Critical Care Course in Children after Liver Transplant

Kukreti

Daoud

Bola

et al. 2014

Critical Care Research and Practice

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“…The presence of two or more of these factors was associated with a significant reduction in graft and patient survival to about 25-40 %. Other series have also noted lower graft survival in children aged less than 2 years with ALF possibly reflecting technical challenges in small babies [20]. This population is the most challenging group, and further improvements in perioperative surgical and intensive care are needed to make progress.…”

Section: Acute Liver Failurementioning

confidence: 99%

Pediatric Liver Transplantation

Heaton

2015

Textbook of Pediatric Gastroenterology, Hepatology and Nutrition

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“…They should be prevented, and if occurred; should be diagnosed and managed early to improve graft and patient outcomes, however, those outcomes are affected also by additional variables (i.e. Large for size graft (LFSG), pediatric end-stage liver disease (PELD)/model for end-stage liver disease (MELD) scores, centre experience/volume, operative time, operative blood loss, blood transfusion units, etc); those variables should be modulated also for getting better short-and long-term outcomes [ 8 , [22] , [23] , [24] , [25] , [26] ] .…”

Section: Introductionmentioning

confidence: 99%