Estimating constituents of optical isomers in mixed solution based on spin Hall effect of light

Abstract

In this paper, an optical method for precisely estimating constituents of optical isomers (OIs) in mixed solution is presented. We convert the composition ratio of OI into polarization-rotation-dependent spin Hall effect of light (SHEL). The theoretical model between the SHEL and OI composition ratio is established in the geometrical-optics picture, and the spatial shift can be measured through weak measurement technique. Based on our theory, the concentrations of glucose and fructose in a mixed solution are separately obtained. Our accurate measurements of the chiral enantiomer composition can provide an avenue for chiral drug synthesis and analysis.

Polarised infrared light enables enhancement of histo-morphological diagnosis of prostate cancer

“…Consequently, corresponding rotation of the second polarizer causes passing of the light through it ( Figure 2). 4 For the polarizing of infrared light we used a Linear Polarizer APIR29-020 (American Polarizers, Inc). In experiments LED was placed outside the prostate gland, from the bottom side, enabling near infrared light to totally penetrate a first polarize film, prostate tissue sample, another polarize film and finally to the CCD camera.…”

Spin Hall Effect of Light: From Fundamentals To Recent Advancements

“…The concentration of glucose and fructose were measured by determining their optical rotations. [ 124,125 ] The polarization of the incident beam in a prism is pre‐rotated by passing through the solutions, and consequently the spin Hall shift is varied in response to the rotation angle. The concentrations of glucose, fructose, and their mixture were measured within the range of 0 to 5 mg mL −1 .…”

Influence of Solvent Properties on the Measurement Accuracy of Specific Rotation of Chiral Molecular Solutions Based on Photonic Spin Hall Effect

“…[22,25,26] Qiu et al used SHEL to verify that this method can realize chiral molecules recognition and detect the concentration of chiral molecular solutions. [25] Zhou et al used SHEL to measure the ratio of optical isomers in the mixed solution. In the range of small optical rotation, the concentration of chiral molecules has a linear relationship with the SHEL.…”

“…With the development of weak measurement technology, spin Hall effect of light has been widely used in refractive index sensing, [ 21,22 ] graphene thickness measurement, [ 23,24 ] precise measurement of optical conductivity of atomically thin crystals, detection of chemical reaction rate, and measurement of ion concentration. [ 22,25,26 ] Qiu et al used SHEL to verify that this method can realize chiral molecules recognition and detect the concentration of chiral molecular solutions. [ 25 ] Zhou et al used SHEL to measure the ratio of optical isomers in the mixed solution.…”