Estimation of Gestosis of Pregnancy (EPH‐Gestosis)

Abstract

Abstract. Systolic and diastolic blood pressure, urinary protein and amount of edema were compared with factors reflecting the prognosis and condition of the newborn in a series of 4404 patients with EPH‐gestosis, collected from the Helsinki University Central Hospital in 1965–1969 and the University Women's Clinic, Würzburg, in 1960–1969. No significant association was observed between slight and moderate edema and the prognosis of the newborn. The systolic blood pressure gave more significant information than the diastolic blood pressure. The amount of urinary protein showed the most consistent correlation with an impaired prognosis. The systolic blood pressure and proteinuria were thus the most significant indicators. An index for estimation of the prognosis in EPH‐gestosis was constructed on this basis. The purpose of this index is to provide a means of assessing the severity of the condition in the initial stage of treatment by exact use of simple observations. The index defines the risk of perinatal mortality, prematurity, asphyxia and smallness for dates in the individual case.

The efficacy of antihypertensive treatment in pregnant women with chronic and gestational hypertension: a population-based study

“…However, intrauterine growth retardation is found more frequently in newborns of hypertensive women, along with an increase of frequency and severity of maternal blood pressure. 24 This finding was confirmed in our study because a 2.2-fold higher risk for low-birthweight newborns was found. In addition, a strong association between severe CH and a higher risk for some pregnancy complications, including threatened abortions, preterm deliveries and placental disorders, was clear in our data set.…”

Prediction of maternal and fetal complications in preeclampsia

“…Older studies have demonstrated a relationship between the degree of albuminuria (6,7) and perinatal outcome, whereas a more recent investigation questions this relationship (8).…”

Antihypertensive Treatment with the Adrenergic Beta-Receptor Blocker Metoprolol during Pregnancy

“…A higher diastolic pressure is associated with higher perinatal mortality and a higher incidence of intrauterine growth retardation (Tervilla et al, 1973). This may be taken as evidence that elevated blood pressure during pregnancy should be treated.…”