“…This modeling was successful and denoising techniques have also been developed: sub-sampling (Zhang et al [48], Zhang [49]), pre-averaging (Podolskij and Vetter [43], Jacod et al [25]), and others (Zhou [50]). There are many studies that treat both non-synchoronicity and market microstructure noise: Malliavin and Mancino [34], Mancino and Sanfelici [35], Park and Linton [42], Voev and Lunde [47], Griffin and Oomen [19], Christensen et al [12,13], Koike [27,29,28], Aït-Sahalia et al [4], Barndorff-Nielsen et al [6], Bibinger [8,9].…”