In the case of adjustable drives systems with an induction motor (IM), a harmonic regime is manifested, whose knowledge and analysis are always necessary. However, most studies are focused on specific drive systems, the results of these works being valid only for drive systems of the same type. The objective of the present paper was to determine the harmonics consequences not only on the technical characteristics of the IM but also on the power supply as well as on the mechanical drive system. Thus, by initiating a methodology for estimating the consequences of each voltage harmonic separately, the aim was to substantiate a generally applicable method, which allows the evaluation, for any application, of the overall effects of the harmonics. The main feature of the method used in this paper was the consideration of the presence of voltage harmonics in the stator voltage of the IM, of certain frequencies and with certain levels, and the determination of all the electrical and mechanical consequences on the model of the drive system. It has been found that the harmonics of the IM affects the power quality (PQ) of the power supply, having significant influences also on the mechanical part of the drive system.