Estimation of total antioxidant capacity levels in saliva of caries-free and caries-active children

Abstract

Background and Objectives:The purpose of this study was to evaluate total antioxidant levels in caries-free and caries-active children.Materials and Methods:The present study included one hundred and twenty healthy children who were divided into two groups; Group I and Group II, comprising of age groups 7 to 10 years and 11 to 14 years. respectively. Both the groups were then sub-divided equally according to gender. They were further divided into caries-free and caries-active children with 15 children in each group. Unstimulated saliva was collected by suction method. The samples were then analyzed for total antioxidant capacity. The data was then statistically analyzed using Student's t-test (unpaired).Results:The results revealed that the total antioxidant capacity of saliva increased significantly in caries-active children when compared to caries-free children.Conclusion:Within the limitation of this study, we can conclude that the physicochemical properties of saliva in particular total antioxidant capacity play a role in the development of caries.

Salivary and Serum Antioxidant and Oxidative Stress Markers in Dental Caries

“…There are also limited studies on salivary TAC in dental caries [Tulunoglu et al, 2006;Hegde et al, 2009;Preethi et al, 2010;Dodwad et al, 2011;Kumar et al, 2011;Mahjoub et al, 2014].…”

Salivary Biomarkers in Caries Affected and Caries Free Children

“…These findings were in agreement with Roa et al, [50] who found no difference in total protein levels between caries-free and caries-active adults. On contrast, Preethi et al, and Dodwad et al, [18,51] have shown that total proteins were significantly higher in caries active in comparison to caries free children. Salivary α-defensin is part of antimicrobial innate immunity.…”

Evaluation of Total Antioxidant Capacity (TAC) of Saliva in Caries Active and Caries free Tribal School Going Children of Wardha District.

“…[1]The reason for increased TAC in caries active tribal children could be : It has been seen that salivary peroxidase system constitutes to be one of the major salivary antioxidant systems. Salivary peroxidase brings about the control of oral bacteria that form dental plaque, to imbalance in the ecology, which lead to dental caries.…”

“…Results of studies on TAC Tulunoglu et al [9] Total antioxidant values were higher in caries active groups Uberos et al [13] Total antioxidant capacity of the saliva of patients with caries in deciduous teeth was greater than among those without caries Prabhakar et al [14] Total antioxidant capacity of saliva increased significantly in caries active children Hegde et al [15] Total antioxidant capacity of saliva increased in children with caries Preethi et al [10] Total antioxidant capacity of saliva increased in caries active children Kumar et al [16] TAC of saliva increased in children with Severe early childhood caries and increasing prevalence of dental caries predisposes to the increase in TAC of saliva Dodwad et al [1] Total antioxidant capacity of saliva increased significantly in cariesactive children when compared to caries-free children Hegde et al1 [7] TAC level increases with increase in severity of caries Ahmadi-Motamayel et al [18] TAC was significantly higher in the saliva of caries active group relative to the caries free subjects Mahjoub et al1 [9] TAC levels and salivary total protein increased in children with severe early childhood caries compared with caries-free children Pandey et al [20] Total antioxidants in saliva increased with caries activity Muchandi et al [21] Salivary TAC increases in patients with early childhood caries Silva et al [22] Salivary Total Antioxidant capacity was higher in children with early childhood caries as compared to caries free children …”

“…The saliva by constantly bathing the oral mucosa and teeth, acts as a cleansing solution, a lubricant, a buffer, and an ion reservoir of calcium and phosphate, which are necessary for remineralization of initial carious lesions. [1] Saliva serves as a mirror of the body's health and has various defense mechanisms such as enzymatic and immunologic defense systems against bacteria, fungi, viruses, protection of mucosa and promotes its healing. One of such important defense mechanism is antioxidants system.…”