Estrabismo y cataratas congénitas

Objective To evaluate the characteristics of strabismus in infants who underwent cataract surgery with and without intraocular lens (IOL) implantation. Design Secondary outcome analysis in a prospective, randomized clinical trial Participants The Infant Aphakia Treatment Study (IATS) is a randomized, multicenter (n = 12) clinical trial comparing treatment of aphakia with a primary IOL or contact lens in 114 infants with a unilateral congenital cataract. Intervention Infants underwent cataract surgery with or without placement of an IOL. Main Outcome Measures The proportion of patients who developed strabismus during the first 12 months of follow-up was calculated using the life-table method, and compared across treatment groups and age strata using a log-rank test. Results Strabismus developed within the first 12 months of follow-up in 38 (life table estimate: 66.7%) pseudophakic infants and 42 (life table estimate: 74.5%) infants treated with contact lenses (p=0.59). The younger cohort (< 49 days) at the time of surgery developed less strabismus (29 of 50, life table estimate: 58.0%) than the older cohort (≥ 49 days) (51 of 64, life table estimate: 80.0%) (p<0.01). Conclusions Intraocular lens placement does not prevent the early development of strabismus following congenital cataract surgery. However, strabismus was less likely to develop in infants whose cataract was removed at an earlier age.

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“…Weisber et al, Hiles and Sheridan, and Merino reported success rates between 75 and 83.3% in older children. 9,15,16 …”

Section: Discussionmentioning

confidence: 99%

One-Year Strabismus Outcomes in the Infant Aphakia Treatment Study

et al. 2013

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“…Cataracthas profound consequenceson the quality of life and with a greater impacton children compared to adults. Untreated cataract predisposes children to ocular comorbidities such as amblyopia [9], strabismus [32], and nystagmus [33]. The associated vision loss could compromiseacademic performance [16,17], social relations [34], career aspiration [35] and mental health [18].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Childhood Cataract and Associated Factors Among a Pediatric Population at A Tertiary Hospital in Ghana

Amankwaa-Frempong

Atia

Kumah

et al. 2022

Preprint

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Background: Childhood cataract unlike adult-related cataract has received a little attention despite the devastating consequences on the early development of the visual system and the overall impact on the quality of life of children. The existence of accurate epidemiological data is a primary step towards management strategies, however, there remains a paucity of data in sub-Saharan Africa including Ghana. Therefore, the study sought to investigate the prevalence of childhood cataract and its associated factors among a pediatric population at a tertiary health facility in Ghana. Methods: The study employed a retrospective electronic medical-record review on 263 pediatric cataract cases examined (from January 2019 to December 2020) at the pediatric ophthalmology department of the Komfo Anokye Teaching Hospital, Kumasi, Ghana. Patient clinical data including sociodemographic, signs and symptoms, primary diagnosis and associated ocular complications were gathered and analyzed using Statistical package and Service Solution (SPSS). Chi-square and regression statistics were used to summarize data at a significance of p< 0.05. Results: The prevalence of childhood cataract was 4.25% (263/6,188). The proportionate distribution of cataracts was congenital (39.5%), traumatic (33.1%) and developmental (26.6%). Over half (51.7%) of the subjects had unilateral cataract. The major complications of childhood cataracts were strabismus (5.70%), nystagmus (3.0%) and retinal detachment (1.90%). Older age (2-12 years, OR = 0.27, p<0.001; > 12 years, OR = 0.12, p<0.001) was significantly associated with reduced odds of congenital cataract. Similarly, increasing age (2-12 years, OR = 12.59, p<0.001; > 12 years, OR = 7.57, p = 0.004) and female sex (OR = 0.58, p = 0.038) was significantly associated with decreased odds of traumatic cataracts. Conversely, older age (2-12 years, OR = 11.02, p<0.001; > 12 years, OR = 26.57, p<0.001) and female sex (OR = 2.27, p = 0.008) were significantly associated with increased odds of developmental cataracts. Conclusion: Our results suggest a higher burden of childhood cataract (approximately four in every hundred children had childhood cataract). This evidence warrants the implementation of pre-school vision screening and eye health education programmes to promote early detection and prevention of avoidable vision impairment and/or blindness within the pediatric population.

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Strabismus in Children with Cataracts

Bothun

2016

Congenital Cataract

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Estrabismo y cataratas congénitas

Cited by 13 publications

References 10 publications

One-Year Strabismus Outcomes in the Infant Aphakia Treatment Study

One-Year Strabismus Outcomes in the Infant Aphakia Treatment Study

Prevalence of Childhood Cataract and Associated Factors Among a Pediatric Population at A Tertiary Hospital in Ghana

Strabismus in Children with Cataracts

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