Estructura genética de poblaciones indígenas del occidente colombiano mediante el uso de marcadores ligados al cromosoma Y

Franco, Fabián Andrés; Barreto, Guillermo

doi:10.18257/raccefyn.476

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…Regarding the Andean populations, they behave completely different from the Amazonian indigenous communities, where the geographical position is very important in structuring the populations. Among their geographical positions are the central, eastern and western mountain ranges, which act as a physical barrier to gene flow in the different populations [74]. It is also important to mention that the Andean populations have a different social organization than those of the Amazon, they do not have linguistic exogamy, which gives greater weight to geographical proximity, speaking in terms of population structuring.…”

Section: Plos Onementioning

confidence: 99%

New Y-SNPs in QM3 indigenous populations of Colombia

Espitia Fajardo,

Rivera Franco,

Braga

et al. 2023

PLoS ONE

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In evolutionary studies of human populations based on the Y chromosome, the majority of Native Americans belong to the QM3 lineage. Therefore, to study the history of groups inhabiting northern South America, it is necessary to have a higher resolution of the tree. The objective of this work was to identify new SNPs of the QM3 lineage that would allow the evaluation of the phylogenetic relationships between Andean and Amazonian populations of Colombia. Sequences previously obtained from two Y chromosomes of Amazonian populations were used, from which 13 potential SNPs were selected and typed in 171 Amazonian samples from the Vaupés region and in 60 samples from the Pasto, Nasa, Embera, Arhuaco and Kogüi ethnic groups of the Andean region. In addition, the main SNPs/markers (L56, L54, M346, M848, Z780, CTS11780) defining autochthonous Q lineages were typed, along with others defined by different SNPs/markers as reported in the literature (CTS11357, SA05, Z19319, Z5915, and Z19384). It was found that all the new SNPs are present in the Amazonian samples and only 2 of them are shared with the Embera, Nasa and Pasto, but none with the Kogüi and Arhuaco from the northern Andes, in the Colombian Caribbean. Combining the 13 variants of the present study with 14 previously reported and using TMRCA, a new QM3 tree proposal is generated. This method makes it possible to increase the number of sublineages of QM3 with a higher resolution and to detect differences between the different populations of Vaupés in the Amazon, as in the case of the Kubeos and Pisamiras, the latter of which is in grave danger of extinction. These new sublineages are useful for microevolutionary studies of the Amerindian populations of South America.

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Section: Plos Onementioning

confidence: 99%

New Y-SNPs in QM3 indigenous populations of Colombia

Espitia Fajardo,

Rivera Franco,

Braga

et al. 2023

PLoS ONE

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Paternal portrait of populations of the middle Magdalena River region (Tolima and Huila, Colombia): New insights on the peopling of Central America and northernmost South America

et al. 2018

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The valley of the Magdalena River is one of the main population pathways in Colombia. The gene pool and spatial configuration of human groups in this territory have been outlined throughout three historical stages: the Native pre-Hispanic world, Spanish colonization, and XIX century migrations. This research was designed with the goal of characterizing the diversity and distribution pattern of Y-chromosome lineages that are currently present in the Tolima and Huila departments (middle Magdalena River region). Historic cartography was used to identify the main geographic sites where the paternal lineages belonging to this area have gathered. Twelve municipalities were chosen, and a survey that included genealogical information was administered. Samples collected from 83 male volunteers were analyzed for 48 Y-SNPs and 17 Y-STRs. The results showed a highly diverse region characterized by the presence of 16 sublineages within the major clades R, Q, J, G, T and E and revealed that 93% (n = 77) of haplotypes were different. Among these haplogroups, European-specific R1b-M269 lineages were the most representative (57.83%), with six different subhaplogroups and 43 unique haplotypes. Native American paternal ancestry was also detected based on the presence of the Q1a2-M3*(xM19, M194, M199) and Q1a2-M346*(xM3) lineages. Interestingly, all Q1a2-M346*(xM3) samples (n = 7, with five different haplotypes) carried allele six at the DYS391 locus. This allele has a worldwide frequency of 0.169% and was recently associated with a new Native subhaplogroup. An in-depth phylogenetic analysis of these samples suggests the Tolima and Huila region to be the principal area in all Central and South America where this particular Native lineage is found. This lineage has been present in the region for at least 1,809 (+/- 0,5345) years.

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Estructura genética de poblaciones indígenas del occidente colombiano mediante el uso de marcadores ligados al cromosoma Y

Cited by 2 publications

References 15 publications

New Y-SNPs in QM3 indigenous populations of Colombia

New Y-SNPs in QM3 indigenous populations of Colombia

Paternal portrait of populations of the middle Magdalena River region (Tolima and Huila, Colombia): New insights on the peopling of Central America and northernmost South America

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