Estudio clínico aleatorizado entre sutura de polidioxanona y de naylon en el cierre de laparotomía en pacientes de riesgo

Docobo-Durantez, Fernando; Sacristán-Pérez, Cristina; Flor-Civera, Blas; Lledó-Matoses, Salvador; Kreisler, Esther; Biondo, Sebastiano

doi:10.1016/s0009-739x(06)70877-6

Cited by 7 publications

(3 citation statements)

References 13 publications

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“…They concluded that abdominal wall closure should be performed with slow-absorption sutures such as PDS since this type of suture has a similar complication rate to non-absorbable sutures [3]. Gaikwad et al declared an alarmingly higher incidence of wound dehiscence in the PDS group than nylon group.…”

Section: Discussionmentioning

confidence: 99%

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A Comparative Study of Polydioxanone and Nylon for Abdominal Wall Closure With Interrupted Figure of Eight in Peritonitis Cases

et al. 2016

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Background: In emergency and elective settings, some surgeons prefer continuous or interrupted closure of abdominal fascia, because in a continuous suturing, cutting out of even a single bite of tissue leads to opening of the entire wound and high risk of burst abdomen, whereas in interrupted method, they found much lower risk of burst abdomen. The aim is to assess the complication rate with the same closure technique between two different sutures. The best suture is one that maintains tensile strength throughout the healing process with good tissue approximation and less wound infection, is well tolerated by patient and is technically simple and expedient. The aim was to compare the non-absorbable sutures (nylon) and delayed absorbable sutures (polydioxanone (PDS)) for abdominal wall closure in cases of peritonitis. We used a different technique to close the abdominal wall fascia and study the postoperative complications.

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Section: Discussionmentioning

confidence: 99%

“…The wound pain was evaluated; in nylon group, it was found to be 30% as compared to 6.7% in PDS group (Table 2 and Table 3 [2][3][4]). However, this difference was found to be statistically insignificant.…”

Section: Observations and Analysismentioning

confidence: 99%

A Comparative Study of Polydioxanone and Nylon for Abdominal Wall Closure With Interrupted Figure of Eight in Peritonitis Cases

et al. 2016

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“…It is completely absorbed into the tissues in 6 months [15] and has 6 weeks’ half-life in its tensile strength [16]. PDS retains its tensile strength well in pancreatic juice [17] and has been reported to have low tissue reactivity [15,18,19,20,21]. This is why PDS is extensively used in pancreatic surgery, and was chosen for the present study investigating not the effects of suturing method, but instead the effects of thread thickness, loop tightness and the number of passes through the pancreas.…”

Section: Discussionmentioning

confidence: 99%

Effects of Diameter, Number and Tightness of Sutures on Pancreatic Injury Response

Lämsä¹,

Jin²,

Nordback³

et al. 2008

Dig Surg

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Background: We have experimental data indicating that the pancreas is easily damaged by any intervention. The present study compared the effects of suture diameter, number of needle passes and suture tightness on rat pancreas. Methods: Under anesthesia, rat pancreas was sutured either with one loose stitch of 6-0 polydioxanone (PDS II) or 3-0 PDS II, with 5 passes of loose running 6-0 PDS II, or with 6-0 PDS II loop tightened to 0.6 or 1.2 N. Amylase activity and pancreatic tissue histology at the suturing site and farther away, were evaluated 1, 3, 7 and 21 days postoperatively. Results: Each suturing exposure and the sham-operation induced temporary amylase activity elevation on day 1 when compared with the baseline. In histology, 3-0 suture, 5 needle passes and 1.2-newton loop induced more damage than 6-0 suture, single needle pass and 0.6-newton loop, respectively. Similar but milder changes were observed in samples from the remote site. Conclusions: The pancreas reacts to suturing with widespread injury response resembling that of acute pancreatitis. In attempting to reduce suturing-induced widespread injury, as few and thin sutures and as loose suture tightness as possible should be used. Although these findings may seem obvious, they have not previously been proven in terms of histology.

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Closure methods for laparotomy incisions for preventing incisional hernias and other wound complications

Patel

Paskar

Nelson

et al. 2017

Cochrane Database of Systematic Reviews

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Estudio clínico aleatorizado entre sutura de polidioxanona y de naylon en el cierre de laparotomía en pacientes de riesgo

Cited by 7 publications

References 13 publications

A Comparative Study of Polydioxanone and Nylon for Abdominal Wall Closure With Interrupted Figure of Eight in Peritonitis Cases

A Comparative Study of Polydioxanone and Nylon for Abdominal Wall Closure With Interrupted Figure of Eight in Peritonitis Cases

Effects of Diameter, Number and Tightness of Sutures on Pancreatic Injury Response

Closure methods for laparotomy incisions for preventing incisional hernias and other wound complications

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