Estudio de 1.595 casos de brucelosis en la provincia de Almería (1972–1998) según datos epidemiológicos de declaración de la enfermedad

García, Pilar Barroso; Pelayo, R. Rodríguez-Contreras; Extremera, Blas Gil; Martin, Allison; Huertas, G. Guijarro; Salguero, Acurio; Carreño, Tapia

doi:10.1016/s0014-2565(02)71152-1

Cited by 14 publications

(11 citation statements)

References 8 publications

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“…The two groups were not significantly different in this respect (P > 0.05). The mean CD 4 + cell count in patients infected with HIV was 803± 656.7 cell/µL (Min: 50 cell/µL, Max: 4546 cell/µL). The mean number of CD 4 + cells in women was higher than that of men, but the difference was not statistically significant (P = 0.6) ( Table 1).…”

Section: Resultsmentioning

confidence: 99%

“…All patients and controls were informed about the study and signed the written consent; 89 HIV positive patients were included in the study, and for each patient a questionnaire was filled out. The questionnaire included demographic information, age, gender, CD 4 + cell count, and duration of the infection since diagnosis of the disease. A 5 mL blood sample was obtained from each patient and serological tests to detect anti-Brucella antibodies were carried out for each sample.…”

Section: Methodsmentioning

confidence: 99%

“…HIV infection was diagnosed using the enzyme-linked immunosorbent assay (ELISA) and then the results were confirmed by the Western Blot method. The number of CD 4 + cells in the infected patients was obtained from their medical file. Since risky behaviors including abusing IV-drugs, was the main route of infection acquisition for most of the patients, co-infection of HBV (Diaplus, San Francisco, USA), HCV (Diaplus, San Francisco, USA), and HTLV-1 (Dima, Goettingen, Germany) were evaluated by the ELISA test (16)(17)(18).…”

Section: Methodsmentioning

confidence: 99%

“…in human is called brucellosis (1,2). The prodromal phase of the disease is two to three weeks, but in some patients may last for several months (3,4). Serological methods for brucellosis diagnosis are of great importance to evaluate the disease prevalence in endemic areas (5,6).…”

Section: Introductionmentioning

confidence: 99%

“…relies upon cellular immune response (9)(10)(11)(12). In HIV infected patients, as the disease progresses, the number of CD 4 + cells decrease, which leads to cellular immune deficiency (13). In brucellosis, elimination of the bacteria from contaminated macrophages is very hard (14).…”

Section: Introductionmentioning

confidence: 99%

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Seroprevalence of Brucellosis in HIV-Infected Patients in Sanandaj, Iran

Rezaee

Rashidi

Ghaedi

et al. 2013

Arch Clin Infect Dis

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Background: Infection with human immunodeficiency virus (HIV) leads to cellular immune deficiency and theoretically patients infected with HIV are susceptible to brucellosis. Objectives: The current study aimed to determine brucellosis rate in the patients infected with HIV. Patients and Methods: We included 89 HIV + patients from Sanandaj Consultation Center for Behavioral Diseases. Patients signed informed written consent before filling out the questionnaire. After serum collection, standard Wright tube, Coombs-Wright and 2ME-Wright tests were performed. Moreover, blood samples obtained from 502 individuals, who were not infected with HIV, were served as the control. Results:The mean age of participants in the experimental and control groups were 33.31 ± 7.47 and 34.38 ± 11.29 years, respectively. In the Wright tube test for the HIV + group, 71 individuals (79.8%) did not have an antibody against Brucella spp., while 18 patients (20.2%) were positive for the antibody. According to the results of Wright tube test for the control group, 63 (12.5%) participants were positive for antiBrucella antibody. The frequency of antibody against Brucella spp. in the HIV + group was significantly higher than that of the control group (P = 0.042). Conclusions: HIV positive individuals in areas endemic for brucellosis must be investigated for the disease.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Seroprevalence of Brucellosis in HIV-Infected Patients in Sanandaj, Iran

Rezaee

Rashidi

Ghaedi

et al. 2013

Arch Clin Infect Dis

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Human Brucellosis and Its Complications

Araj

2015

Neurobrucellosis

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Seroprevalence of camel brucellosis (Camelus dromedarius) in Somaliland

Ghanem

El-Khodery

Saad³

et al. 2009

Trop Anim Health Prod

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The present study was delineated to investigate the prevalence and risk factors of camel brucellosis in Northern Somalia (Somaliland). The study was carried out at three main districts of camel-rearing regions of Somaliland (Awdal, Waqoyi Galbed and Togdheer) in the period from July to November, 2008. A total of 1246 camel blood sera were randomly collected from 42 sporadic small scale camel herds. Two serological tests were used to screen all serum samples, Rose Bengal Plate Test (RBPT) and indirect ELISA (I-ELISA). Multivariate logistic regression was constructed to study the risk factors associated with Brucella seropositive cases. The overall prevalence of camel brucellosis in districts under investigation was 3.9% by RBPT and 3.1% by (I-ELISA). Multivariate logistic regression on animal level showed that locality (P < 0.05; OR: 6.254; CI, 1.186-32.976), herd size (P < 0.001; OR: 5.493; CI, 2.956-10-207), rearing with other ruminants (P < 0.001; OR: 12.433; CI, 3.957-39.060), and contact with other camels (P < 0.05; OR: 5.311; CI, 1.093-25.800) were the potential risk factors. However, herd size (P < 0.05; OR: 5.425; CI, 1.181-24.932), and rearing with other ruminants (P < 0.05; OR: 20.466; CI, 1.456-28.638) were recorded as risk factors on the herd level. The results of the present investigation indicate that the Brucella spp. exists within the camel herds in Somaliland. Further studies need to be done on Brucella infection in the other ruminants to determine which measure should be followed for control of brucellosis.

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Estudio de 1.595 casos de brucelosis en la provincia de Almería (1972–1998) según datos epidemiológicos de declaración de la enfermedad

Cited by 14 publications

References 8 publications

Seroprevalence of Brucellosis in HIV-Infected Patients in Sanandaj, Iran

Seroprevalence of Brucellosis in HIV-Infected Patients in Sanandaj, Iran

Human Brucellosis and Its Complications

Seroprevalence of camel brucellosis (Camelus dromedarius) in Somaliland

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