Estudio de enfermedad celíaca en pacientes con psoriasis

H, Perla Calderón; A, Pilar Valdés; D., Viviana Zemelman; T, Jaime Poniachik; H, Carmen Hurtado; Garmendia, María Luisa; G, Patricia Abumohor; P, María Cristina Echavarri

doi:10.4067/s0034-98872007001000010

Cited by 7 publications

(4 citation statements)

References 38 publications

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“…anti-gliadin antibodies, AGAs) and the setting, including the design as single-centre studies performed in tertiary centres [8,9,10,11,12,13,14,20]. …”

Section: Discussionmentioning

confidence: 99%

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Association between Coeliac Disease and Psoriasis: Italian Primary Care Multicentre Study

Bastiani¹,

Gabrielli

Lora³

et al. 2015

Dermatology

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Background: Studies assessing the association between coeliac disease (CD) and psoriasis show conflicting results. Objective: To assess in the primary care setting the prevalence of CD in patients with psoriasis and the response to a gluten-free diet (GFD) in subjects with psoriasis and CD. Methods: We enrolled 218 patients with psoriasis and 264 controls. Coeliac screening was carried out in all subjects (Eurospital, Trieste, Italy). In subjects with a positive serology, the diagnosis of CD was confirmed histologically. Results: Nine (4.1%) psoriatic patients had positive anti-tissue transglutaminase antibodies compared to only 1 among controls (0.4%, p < 0.05; OR 2.03, 95% CI 1.42-90.11). The diagnosis of CD was confirmed histologically in all 10 subjects. At 6 months GFD was associated with a great improvement of skin lesions in 7 out of 8 patients with psoriasis. Conclusion: Our multicentre primary care study showed an high prevalence of CD in psoriasis and an improvement of skin lesions in CD under GFD.

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“…anti-gliadin antibodies, AGAs) and the setting, including the design as single-centre studies performed in tertiary centres [8,9,10,11,12,13,14,20]. …”

Section: Discussionmentioning

confidence: 99%

“…Several studies investigating the possible association between CD and psoriasis were subsequently published. However, due to contrasting data the available results are inconclusive [8,9,10,11,12,13,14]. Most of the few available data on the effects of GFD on psoriatic skin lesions are contained in case reports [14,15,16,17].…”

Section: Introductionmentioning

confidence: 99%

Association between Coeliac Disease and Psoriasis: Italian Primary Care Multicentre Study

Bastiani¹,

Gabrielli

Lora³

et al. 2015

Dermatology

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“…Para el diagnóstico de la EC, Heredia, Castro y Palma (2007), proponen basarse en la clínica, en los marcadores serológicos y en la biopsia de intestino delgado, la cual continúa siendo el patrón de oro para la mayoría de los investigadores, a lo que se añade que la solicitud de estudios genéticos es recomendada solo a familiares de primer grado de un paciente celíaco. Calderón, et al (2007), señalan que el diagnóstico de EC requiere del uso combinado de la clínica, marcadores serológicos, además de una biopsia de intestino delgado, que puede demostrar desde infiltrado linfocitario en el epitelio hasta atrofia de vellosidades.…”

Section: Discussionunclassified

Auditoria clínica para el diagnóstico de la enfermedad celiaca

Montero

Escalante

2014

Revenf

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RESUMENLa enfermedad celíaca es una inflamación crónica de la mucosa del intestino delgado por intolerancia al gluten. Hasta hace poco se había considerado como una enfermedad infrecuente, pero con el aumento de la sospecha clínica y el advenimiento de nuevas pruebas serológicos, han permitido una mayor facilidad en el diagnóstico y aumento de los casos detectados, por lo que hoy se sabe que es una condición de alta frecuencia. Sin embargo, en Costa Rica no existe un protocolo para que los médicos realicen su diagnóstico, por lo que el objetivo de esta investigación, es conocer la opinión de médicos que laboran en hospitales pertenecientes a la Caja Costarricense de Seguro Social sobre la definición de la EC, sus manifestaciones y exámenes diagnósticos necesarios para descartar o confirmar la presencia de esta enfermedad y posteriormente, dar a conocer las recomendaciones dadas según las Guías de Práctica Clínica y la mejor evidencia científica sobre la realización del diagnóstico de la enfermedad celiaca. Se determinó que las Guías de Práctica Clínica y la evidencia científica coinciden en que el diagnóstico de esta enfermedad requiere del uso combinado de la clínica (lo que requiere amplio conocimiento de los distintos patrones de presentación de la enfermedad), marcadores séricos, además de una biopsia de intestino delgado. La realización de investigaciones como ésta, ayuda a superar las dificultades que interfieren en la adecuación de la práctica clínica a la evidencia científica y poner en marcha estrategias de mejora, que contribuyan al fortalecimiento y selección del mejor criterio clínico, lo que tendrá un impacto directo y positivo sobre la atención de los pacientes.Palabras clave: Enfermedad celiaca, diagnóstico médico, auditoria clínica, guías de práctica clínica, medicina basada en evidencia.

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“…[20][21][22] It has long been accepted that psoriasis is not confined to the skin, also affecting nails and joints, but recent studies have proposed psoriasis as a systemic illness, with multiple organ system involvement. 23 Epidemiological studies have shown an increase in the prevalence of celiac disease in patients with psoriasis, 19,20,[24][25][26] including a case-control study of 12,502 patients with psoriasis, which demonstrated an association (odds ration [OR] = 2.70) in all age groups, although the association strength decreased as age increased. 27 Similarly, a case-control study of 11,793 children diagnosed with celiac disease <20 years of age, between 1969 and 2008, demonstrated a significant risk of developing psoriasis later in life (hazard ration [HR] = 2.05), and 51.3% of psoriasis could be attributed to the underlying celiac disease 20 (Table 1).…”

Section: Psoriasismentioning

confidence: 99%

Could it be gluten? Additional skin conditions associated with celiac disease

2021

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Celiac disease is a multifactorial, inflammatory disorder initiated and sustained by the ingestion of gluten. Occurring across a broad population, the intestinal and extraintestinal manifestations of celiac disease are variable in severity and may be nonspecific in presentation. Given that environmental, genetic, and immune factors involved in the pathogenesis of celiac disease that the digestive tract and skin share many characteristics, and with a prevalence of 0.5-1% in most populations, it is reasonable to consider varying presentations of skin conditions that are linked with celiac disease. The association between celiac disease and skin conditions has been discussed earlier, but new studies have emerged suggesting cutaneous involvement in addition to dermatitis herpetiformis.We review the current literature identifying the relationship and potential mechanisms between celiac disease and various skin conditions.

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Estudio de enfermedad celíaca en pacientes con psoriasis

Cited by 7 publications

References 38 publications

Association between Coeliac Disease and Psoriasis: Italian Primary Care Multicentre Study

Association between Coeliac Disease and Psoriasis: Italian Primary Care Multicentre Study

Auditoria clínica para el diagnóstico de la enfermedad celiaca

Could it be gluten? Additional skin conditions associated with celiac disease

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