Our understanding of Chalcolithic settlements in southern Iberia (c. 3200–2200 bce) has changed dramatically in recent decades. Instead of clearly bounded and dense settlements, archaeology is establishing a range of site types, some sparsely settled, some quite large. Such varied settlement typology is now understood as being part of a thriving period of development, which included monumental tombs, high-quality craft organisation and highly dynamic exchange networks. This article presents recent work around the River Antas in Almeria, Spain, which has revealed a complex settlement network along the river for the period in question. This new evidence challenges our understanding of prehistoric habitation in the area and poses new questions about major settlement pattern changes in the prehistory of the region.