Estudo Epidemiológico E De Concordância Diagnóstica Entre a Citologia, Colposcopia E Histopatologia, Em Pacientes Com Diagnóstico De Papilomavírus Humano.

Abstract

Estudo epidemiológico e de concordância diagnóstica entre a citologia, colposcopia e histopatologia, em pacientes com diagnóstico de Papilomavírus Humano.Epidemiological study and diagnostic compatibility among cytology, colposcopy and histopathology in patients with Human Papillomavirus diagnosis. ABSTRACTThe diagnosis of intraepithelial lesions and carcinoma of the cervix is performed by combining three methods, namely cytology, colposcopy, and histology. The present study represents a retrospective and descriptive cross-sectional epidemiological study of patients' charts with cytological and colposcopic findings compatible with HPV infection, at the Potengi Clinic, in the year 2012 (Natal/RN). We analyzed 111 medical records of patients diagnosed with HPV and the data collected were age, menarche, the onset of sexual life, marital status, sexual partners, contraceptive methods used and results of cytological, colposcopic and histopathological exams. Patients had a mean age of 30 years, most of whom were married (71.2%), menarche at 12-year-old, and sexual debut at approximately 17 years, with a mean of 9.4 partners. About 38% of them use oral contraceptives, 37% do not use any method and only 10% use condoms. The concordance between cytology and colposcopy and between cytology and histology was very significant (rs=0,953; p<0,05). From the analysis of the present study, it can be concluded that the association of cytological, colposcopic and histological methods is more efficient in the diagnosis of lesions caused by viruses such as HPV and carcinoma and should, therefore, be used together. RESUMOO diagnóstico das lesões intraepiteliais e do carcinoma do colo uterino é realizado mediante a associação de três métodos, que são a citologia, colposcopia e histologia. O presente estudo representa uma pesquisa epidemiológica transversal retrospectiva e descritiva de prontuários de pacientes com achados citológicos e colposcópicos, compatíveis com a infecção por HPV, atendidas na clínica Potengi, no ano de 2012 (Natal, RN). Foram analisados 111 prontuários de pacientes diagnosticadas com HPV e os dados coletados foram idade, menarca, início da vida sexual, estado civil, parceiros sexuais, métodos contraceptivos utilizados e resultados de exames citológicos, colposcópicos e histopatológicos. As pacientes tinham média de idade 30 anos, sendo a maioria casada (71,2%), com menarca aos 12

Description of Referrals for Colposcopy in a Hospital in Brazil

“…These results are similar to those observed in the project 12 made for the standardization of the terminology of HPV-Lower Anogenital Squamous associated lesions, in which they found the alterations LSIL, HSIL and high-grade squamous intraepithelial lesions not excluding epidermoid carcinoma (HSIL/CA) in higher frequency, corresponding to 99.1% of the total lesions. [13][14][15] A sensitivity of 70.5% and specificity of 77.8% was found for cytology, demonstrating its value as a screening test for these types of lesions. The PPV of 75.7% is in line with what was observed in the literature searched in a cross-sectional observational study 16 performed in a Women Health Center in the state of Piauí, Brazil, with a PPV index for cytology ranging from 62.2% to 85%.…”

“…These results are similar to those observed in the project 12 made for the standardization of the terminology of HPV- Lower Anogenital Squamous associated lesions, in which they found the alterations LSIL, HSIL and high-grade squamous intraepithelial lesions not excluding epidermoid carcinoma (HSIL/CA) in higher frequency, corresponding to 99.1% of the total lesions. 13 14 15 …”

Citologia, Colposcopia E Histologia

“…Esses achados foram corroborados por um outro estudo epidemiológico desenvolvido com 111 pacientes que realizaram exame citológico, colposcópico e histopatológico. Neste estudo, verificou-se que a colposcopia, apresentou maior prevalência de alterações menores em relação aos achados maiores, corroborando com os laudos citopatológicos 9 .…”