Estudo Espectrofotométrico Da Atividade Foto-Protetora De Extratos Aquosos De Achillea Millefolium, Brassica Oleracea Var. Capitata, Cyperus Rotundus, Plectranthus Barbatus, Porophyllum Ruderale (Jacq.)

Rosa, Marcelo Barcellos da; Oliveira, Tancredo G. de; Carvalho, Camilo Amaro de; Silva, Fabiano D.; Carvalho, Leandro Machado de; Nascimento, Paulo Cı́cero do; Peres, Rodrigo L.

doi:10.5216/ref.v5i1.4620

Cited by 15 publications

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“…Currently, there has been great interest in using plant compounds in sunscreens, especially when they exhibit antioxidant activity (Polonini, Raposo, Brandão, 2011). Thus, flavonoids, tannins, and other phenolic compounds are studied in relation to photoprotective capacity, once they present absorption in the ultraviolet region (Rosa et al, 2008;Violante et al, 2009). Since the extract of C. officinalis present phenolic compounds in its composition, cream and gel formulations were evaluated for this capacity.…”

Section: Resultsmentioning

confidence: 99%

Physical chemistry evaluation of stability, spreadability, in vitro antioxidant, and photo-protective capacities of topical formulations containing Calendula officinalis L. leaf extract

Deuschle

Bortoluzzi

et al. 2015

Braz. J. Pharm. Sci.

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Calendula is used widely in cosmetic formulations that present phenolic compounds in their chemical constitution. The objective of our research was to develop and evaluate the stability of topical formulations containing 5% hydro-ethanolic extract of calendula leaves, including spreadability, and in vitro photo-protective, and antioxidant capacity. To evaluate the stability, we used organoleptic characteristics, pH, and viscosity parameters. Antioxidant capacity was measured by the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, and the photo-protective capacity by SPF spectrophotometric measure. All formulations were stable. The calendula extract formulations in gel and cream showed no significant variations in pH, and the cream formulations presented lower viscosity variations than gel formulations. The spreadability of the gel formulations was superior to those in cream. The formulations also presented good antioxidant capacities and an FPS of around 1.75. In accordance with the results, the formulations can be used as antioxidants, but considering the low SPF obtained, calendula cannot be considered as a stand-alone sunscreen, yet may well be tested in future studies towards verifying enhancement of synthetic sunscreens.

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Section: Resultsmentioning

confidence: 99%

Physical chemistry evaluation of stability, spreadability, in vitro antioxidant, and photo-protective capacities of topical formulations containing Calendula officinalis L. leaf extract

Deuschle

Bortoluzzi

et al. 2015

Braz. J. Pharm. Sci.

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“…Antioxidant activity of Piper umbellata L. was reported by Baldoqui et al (2009), and was attributed to the presence of 4-nerolidylcathecol, which exhibits antioxidant activity as potent as that of alpha-tocopherol. Rosa et al (2008) assessed the photoprotective potential of aqueous extracts of different plants by methodology of Mansur et al 1986. They showed that the presence of phenolic compounds, tannins, flavonoids, coumarins, cardiotonic glycosides, reducing sugars, triterpenes, and steroids in extracts of Achillea millefolium L., Brassica oleracea var.…”

Section: Phytochemicals In Photoprotectionmentioning

confidence: 99%

“…Cass., and Sonchus oleraceus (L.) L. resulted in significant increases in SPF values, with SPF 8 for A. millefolium; SPF 6 for S. oleraceus; SPF 5 for P. ruderale, B. oleracea var. capitata, and P. barbatus; and SPF 2 for C. rotundus (Rosa et al 2008). In the case of these values, the combination of several of these compounds, or in combination with synthetic sunscreens, may be beneficial as SPF values of 15 or higher are recommended for sun exposure (USFDA 2017, 2019).…”

Section: Phytochemicals In Photoprotectionmentioning

confidence: 99%

“…Aqueous extract 1 µL/mL 8 (Rosa et al 2008) Green propolis and red propolis Ethanolic and glycolic extract in a gel 0.2 µL/mL 2.2-5.8 (Nascimento et al 2009) Pothomorphe umbellate root Crude ethanol-water extract 0.2 µg/mL 21 (Da Silva et al 2005) Sonchus oleraceus Aqueous extract 1 µL/mL 6 (Rosa et al 2008) Brassica oleracea Aqueous extract 1 µL/mL 5 (Rosa et al 2008) Porophyllum ruderale Aqueous extract 1 µL/mL 5 (Rosa et al 2008) Plectranthus barbatus Aqueous extract 1 µL/mL 2 (Rosa et al 2008) Cyperus rotundus Aqueous extract 1 µL/mL 1 (Rosa et al 2008) Rutin -0.1% 1.1 (Velasco et al 2008) Passiflora incarnata Dry extract 1.68% 1.2 (Velasco et al 2008) Plantago lanceolata Hydroglycolic extract 2.78% 1.1 (Velasco et al 2008) Dracocephalum moldavica Ethyl acetate extract 2 mg/mL 24.79 (Khazaeli & Mehrabani 2008) Viola tricolor Ethyl acetate extract 2 mg/mL 25.69 (Khazaeli & Mehrabani 2008) Moringa oleifera Aqueous extract 4.0% 2.01 (Baldisserotto et al 2018) Capnophyllum peregrinum Crude methanolic extract 2 mg/mL 35.21 (Lefahal et al 2018) demonstrated by several previous studies (Wagner 2011). The SPF value is dependent on the molecule(s) present in the extracts that exhibit photoprotection ability, the method of extraction, the concentration of the substances, and the solvent or system in which it is incorporated.…”

Section: Achillea Millefoliummentioning

confidence: 99%

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Can natural products improve skin photoprotection?

et al. 2020

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Due to increased UV radiation on the Earth’s surface, caused by depletion of the stratospheric ozone, people have become more susceptible to different types of skin damage, such as erythema, sunburns, and cancer; this is especially of concern in tropical countries. Thus, efforts to improve awareness as well as the use of sunscreen are increasing worldwide. However, synthetic UV filters have been associated with deleterious effects such as photosensitization. Natural products have been used by ancient cultures for several purposes, including protecting the skin from the sun. However, there is still doubt today whether photoprotection is a real phenomenom or whether it is simply tanning of the skin. Plants have self-protective mechanisms and produce secondary metabolites that can protect themselves from UV radiation. Yet, can phytochemical compounds protect human skin? This review discusses the paradoxical effect of chemical UV filters and the influence of phytochemicals in in vitro and in vivo tests of photoprotection.

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“…A análise espectral a partir da concentração de 10% (massa de planta triturada/volume de água) demonstrou que os extratos promoveram fotoproteção nas regiões, tanto UVA, quanto UVB, resultando em FPS aproximadamente, de 8 para Achillea, 6 para Sonchus, 5 para Porophyllum e Brassica, 2 para Plectranthus e 1 para Cyperus. Os autores concluíram que estudos como este, são relevantes na pré-seleção de espécies vegetais que apresentam potencial de FPS de forma conveniente e de custo reduzido(ROSA et al, 2008).…”

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Síntese e avaliação da segurança in vitro da rutina e do succinato de rutina visando sua incorporação em formulações fotoprotetoras eficazes associados a filtros químicos e físico

Pedriali¹

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Dedico este trabalho... a Deus, pelo dom da vida, por todas as oportunidades que me concedeu e pela força para superar as dificuldades. Ao meu querido companheiro e esposo Dante, com seu exemplo me mostrou outras maneiras de ver as coisas, me apoiou e juntos superamos as dificuldades desta jornada. Aos meus pais Fátima e Antonio pelo cuidado e proteção, por todo o sacrifício que passaram para que me proporcionassem até chegar neste momento. Às minhas irmãs queridas Tatiane e Marcelle que sempre me apoiaram. Aos meus queridos sobrinhos: Vitória e Kaio. Aos meus avós Nair e Francisco, Natalino (in memorian) e Lúcia (in memorian) que mesmo não presentes fisicamente estiveram juntos em atitudes, pensamentos e gestos. Aos meus queridos amigos (irmãos de coração) que são tão importantes para mim pelo apoio, carinho e incentivo em todos os momentos: Karla, Airam, Paulo, Tatiana, Paula e Robson À Psicanálise e aos psicanalistas que estiveram junto comigo neste período de minha vida, que me proporcionaram um olhar mais profundo de mim mesma e com isto um caminhar mais leve e seguro. v AGRADECIMENTOS À minha orientadora e professora, Drª. Maria Valéria Robles Velasco por ter confiado em mim, pelo apoio e incentivo disponibilizados durante estes anos de convivência. Ao professor, Dr. André Rolim Baby pela oportunidade concedida na área da Cosmetologia e pela amizade de longo tempo. Aos professores que participaram da banca de qualificação, Dr. Marcos Antonio Correa (FCF/UNESP) e Drª. Gislaine Ricci Leonardi (UNIFESP/Diadema) pelos ensinamentos, pela confiança e pelos apontamentos realizados. Aos professores encontrados no Congresso XX COLAMIQC, Dr. Marlus Chorilli (FCF/UNESP) e Drª. Gislaine Ricci Leonardi (UNIFESP/Diadema) pelos exemplos e ensinamentos deixados. Às minhas estagiárias e amigas Samara Suemi Iizuka, Raquel Omegna Gago Madruga e Denise Pelegrini Veronezi que se mostraram sempre prestativas e colaboraram em partes deste trabalho. Ao Pesquisador Adjaci Uchoa Fernandes: Instituto de Química (IQ/USP), pela análise dos dados espectros de RMN. Às técnicas do laboratório de Cosmetologia: Claudinéia Aparecida Sales de Oliveira Pinto e Carla Aparecida Gonçalves pelo apoio e atenção disponibilizados. Aos antigos amigos (fase de transição entre o Mestrado e Doutorado): Dayane,

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Estudo Espectrofotométrico Da Atividade Foto-Protetora De Extratos Aquosos De Achillea Millefolium, Brassica Oleracea Var. Capitata, Cyperus Rotundus, Plectranthus Barbatus, Porophyllum Ruderale (Jacq.)

Cited by 15 publications

References 0 publications

Physical chemistry evaluation of stability, spreadability, in vitro antioxidant, and photo-protective capacities of topical formulations containing Calendula officinalis L. leaf extract

Physical chemistry evaluation of stability, spreadability, in vitro antioxidant, and photo-protective capacities of topical formulations containing Calendula officinalis L. leaf extract

Can natural products improve skin photoprotection?

Síntese e avaliação da segurança in vitro da rutina e do succinato de rutina visando sua incorporação em formulações fotoprotetoras eficazes associados a filtros químicos e físico

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