Ethanol Extracts from Mistletoe (&lt;i&gt;Viscum album&lt;/i&gt; L.) Act as Natural Antioxidants and Antimicrobial Agents in Uncooked Pork Patties during Refrigerated Storage

Kang, Suk-Nam

doi:10.5713/ajas.15.0253

Cited by 15 publications

(8 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite the experimental differences described, Abies alba dry extract showed a similar average amount of total flavonoid content when compared to VA var. coloratum [43]. Consequently, the methodology applied in the present work could be suggested as a quality parameter for the VA ethanolic and dry extracts.…”

Section: Determination Of Total Flavonoid Contentmentioning

confidence: 93%

Thermoresponsive Hydrogel Containing Viscum album Extract for Topic and Transdermal Use: Development, Stability and Cytotoxicity Activity

et al. 2021

View full text Add to dashboard Cite

Viscum album L. (Santalaceae), also known as European mistletoe, is a semi-parasitic plant that grows on different host trees. Our group recently demonstrated the antitumoral activity of ethanolic V. album extracts in vitro, depending on the dose and the host tree, V. album ssp abietis from Abies alba being the most active extract. The goal of this work focused on the development of a new topical formulation containing V. album extracts, evaluation of in vitro toxicity and ex vivo skin permeation assays. The Poloxamer 407 hydrogel containing 5% of dry (VA_DEH) or aqueous (VA_AEH) extract presented dermal compatible pH and microbiological stability for 180 days. The hydrogels flow curve presented a non-linear relation, characteristic of non-Newtonian fluids, and the mean viscosity for the VA_DEH and VA_AEH was 372.5 ± 7.78 and 331.0 ± 2.83 Pa.s, respectively, being statistically different (Welch’s t test; p < 0.01). Additionally, WST-1 in vitro assays revealed a dose-dependent toxicity for both formulations and VA_DEH presented a higher activity than the VA_AEH. The promising cytotoxic potential of VA_DEH lead to the ex vivo skin permeation assay with 2.73 ± 0.19 µg/cm2 of chlorogenic acid, which permeated at 8 h, showing a transdermal potential. These in vitro results support the idea that VA_DEH is a novel promising candidate for mistletoe therapy. Therefore, further in vivo and pre-clinical experiments should be performed to evaluate the safety and efficacy of this new dermic delivery system.

show abstract

Section: Determination Of Total Flavonoid Contentmentioning

confidence: 93%

Thermoresponsive Hydrogel Containing Viscum album Extract for Topic and Transdermal Use: Development, Stability and Cytotoxicity Activity

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Hydrogen peroxide can be further converted to oxygen and water by catalase and glutathione peroxidase. Superoxide radicals have been observed to inactivate enzymes, degrade DNA, kill cells, and damage cell membranes [24]. The antioxidant activity of rosemary extract was stronger than the superoxide anion scavenging activity.…”

Section: Resultsmentioning

confidence: 99%

Potential antiviral agents of Rosmarinus officinalis extract against herpes viruses 1 and 2

et al. 2020

View full text Add to dashboard Cite

Herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) belong to the herpesviridae family and cause neurological disorders by infecting the nervous system. The present study aimed to investigate the effects of Rosmarinus officinalis L. (rosemary) extract against HSV-1 and HSV-2 in vitro. The antioxidant activity of this extract was investigated by superoxide anion and 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical assays. Rosemary extract was evaluated by an HSV-1 antiviral assay, in which viral replication in Vero cells was determined and quantified using a cytopathic effect assay. The present study showed that rosemary extract at 30 µg/ml caused 55% inhibition of HSV-1 plaques, whereas 40 µg/ml rosemary extract caused 65% inhibition of HSV-2 plaques. The extracts completely inhibited HSV-1 and HSV-2 plaque formation at 50 µg/ml. Scavenging activity of the superoxide anion radical was observed at 65.74 mg/ml, whereas 50% scavenging activity of the DPPH radical was observed at 67.34 mg/ml. These data suggest that rosemary extract may be suitable as a topical prophylactic or therapeutic agent for herpes viral infections. However, further research is required to elucidate the plant’s active constituents, which may be useful in drug development.

show abstract

“…A recent study also proposed the use of Viscum album ethanolic extracts (semiparasitic on the host tree Quercus acutissima ) as a natural source of antioxidants/preservatives in uncooked meat products. This is due to various antioxidant assays (free radical scavenging activity, superoxide anion radical scavenging and hydroxyl radical scavenging activity) supporting the antioxidant potential of Viscum album extracts due to their high phenolic and flavonoid contents [93].…”

Section: Ethnomedicinal Usesmentioning

confidence: 99%

Parasitic Mistletoes of the Genera Scurrula and Viscum: From Bench to Bedside

et al. 2016

View full text Add to dashboard Cite

Abstract:The mistletoes, stem hemiparasites of Asia and Europe, have been used as medicinal herbs for many years and possess sophisticated systems to obtain nutrients from their host plants. Although knowledge about ethnomedicinal uses of mistletoes is prevalent in Asia, systematic scientific study of these plants is still lacking, unlike its European counterparts. This review aims to evaluate the literature on Scurrula and Viscum mistletoes. Both mistletoes were found to have anticancer, antimicrobial, antioxidant and antihypertensive properties. Plants from the genus Scurrula were found to inhibit cancer growth due to presence of phytoconstituents such as quercetin and fatty acid chains. Similar to plants from the genus Viscum, Scurrula also possesses TNFα activity to strengthen the immune system to combat cancer. In line with its anticancer activity, both mistletoes are rich in antioxidants that confer protection against cancer as well as neurodegeneration. Extracts from plants of both genera showed evidence of vasodilation and thus, antihypertensive effects. Other therapeutic effects such as weight loss, postpartum and gastrointestinal healing from different plants of the genus Scurrula are documented. As the therapeutic effects of plants from Scurrula are still in exploration stage, there is currently no known clinical trial on these plants. However, there are few on-going clinical trials for Viscum album that demonstrate the functionalities of these mistletoes. Future work required for exploring the benefits of these plants and ways to develop both parasitic plants as a source of pharmacological drug are explained in this article.

show abstract

Ethanol Extracts from Mistletoe (<i>Viscum album</i> L.) Act as Natural Antioxidants and Antimicrobial Agents in Uncooked Pork Patties during Refrigerated Storage

Cited by 15 publications

References 44 publications

Thermoresponsive Hydrogel Containing Viscum album Extract for Topic and Transdermal Use: Development, Stability and Cytotoxicity Activity

Thermoresponsive Hydrogel Containing Viscum album Extract for Topic and Transdermal Use: Development, Stability and Cytotoxicity Activity

Potential antiviral agents of Rosmarinus officinalis extract against herpes viruses 1 and 2

Parasitic Mistletoes of the Genera Scurrula and Viscum: From Bench to Bedside

Contact Info

Product

Resources

About