This study aims to inventory the diversity of biological resources of medicinal plants utilized by Lampung tribe in West Lampung Regency. Data obtained through semi-structured interview methods and observation. Medicinal plants used by Lampung tribe in West Lampung Regency were 50 species which were divided into 22 families. The most used plant parts were leaves (43.55%). Types of diseases that can be treated include swollen wound, scabies, fever, headache, achy body, sprue, dry cough, clear eye medication, kill diseases or poisons from food, stomachache, diarrhea, chronic ulcer, gastricache, bloated, heal wound, dry wound, cold, boils, back pain, wasp stung, taken to cure postpartum, wipe, cough with phlegm, tooth braces, heal baby's belly button, busela, prevent gray hair, bathe the baby, facilitate breastfeeding, reduce sprains after massage, and appendicitis. Processing of medicinal plants by boiling is the most used method (28.38%). The majority of medicinal plants are used by drinking (33.33%).