Ethnomedicinal study, phytochemical characterization, and pharmacological confirmation of selected medicinal plant on the northern slope of Mount Wilis, East Java, Indonesia

Bhagawan, Weka Sidha; SUPROBORINI, ARUM; PUTRI, DENTHA LORENZA PRASTYA; NURFATMA, AISSYAH; PUTRA, ROY TRI

doi:10.13057/biodiv/d230855

Cited by 8 publications

(12 citation statements)

References 37 publications

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“…Use value (UV) merupakan nilai yang digunakan untuk mengukur tingkat kepentingan relatif pada tanaman yang memiliki khasiat berdasarkan peringkat [3]. Sebagian besar jahe digunakan dengan rute oral [9]- [11], dengan cara merebus atau memotong dan menumbuk serta membasahi bagian rimpang dari jahe [10], [11]. Jahe digunakan untuk mengatasi nyeri oleh masyarakat di berbagai tempat di Indonesia.…”

Section: Zingiber Officinaleunclassified

“…Jahe digunakan untuk mengatasi nyeri oleh masyarakat di berbagai tempat di Indonesia. Masyarakat di desa Gunung Wilis, Jawa Timur, menggunakan jahe untuk meredakan nyeri saat menstruasi [10]. Sedangkan pada masyarakat Rongkong, Sulawesi Selatan, dan Lamaknen, NTT, jahe digunakan untuk mengurangi sakit kepala [9], [11].…”

Section: Zingiber Officinaleunclassified

“…Kunir juga telah digunakan dalam pengobatan tradisional Cina (TCM) sebagai pengobatan, pencegahan dan manajemen dari berbagai penyakit [20]. Di Gunung Wilis, Jawa Timur, rimpang kunir digunakan sebagai analegesik untuk mengatasi nyeri menstruasi dengan nilai UV 0,45 [10]. Sedangkan di Gunung Kidul, Yogyakarta, selain untuk nyeri menstruasi kunir juga digunakan untuk mengatasi nyeri pada perut dan nyeri otot dengan UV 0,13 [8].…”

Section: Curcuma Longaunclassified

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Kajian Literatur: Etnomedisin sebagai Analgesik di Indonesia

Andanalusia,

Izzatul Mukhlishah

2023

JSSCR

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Ethnomedicine has a major role in the development of new drugs. Based on ethnomedicine studies, it is known that some plants’ biological activity has potential as a therapy. One of its activities is as an analgesic, which can help to deal with frequent pain incidents in the world. The purpose of this literature review was to collect information on the use of ethnomedicine as an analgesic in several regions in Indonesia. The method used was narrative review using the Google Scholar database with publication limits from 2019 to 2023. There were nine studies that meet the criteria and represent the western, central and eastern parts of Indonesia. A total of four studies show that Zingiber officinale is used as an analgesic with UV 0.02-1.0. Three studies show Alpinia galanga and Piper betle are used as analgesic with UV 0.4-1.77 and 0.06-1.20, respectively. Two studies show that Oriza sativa and Curcuma longa are used by the local people as analgesics with a UV of 0.04-1.40 and 0.13-0.45, respectively. Other plants that have high UV in several regions include Orthosiphon aristatus (0.80); Curcuma viridiflora (4.00); Ficus septica (0.43), and Emelia ribes (0.60) Based on the results, it is known that Zingiber officinale, Alpinia galanga, Piper betle, Oriza sativa, and Curcuma longa are the plants most widely used as analgesics in several regions in Indonesia. This literature review can be used as a consideration in finding analgesic support therapy using ethnomedicine.

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Section: Zingiber Officinaleunclassified

Section: Curcuma Longaunclassified

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Kajian Literatur: Etnomedisin sebagai Analgesik di Indonesia

Andanalusia,

Izzatul Mukhlishah

2023

JSSCR

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“…Therefore, research on the chemical composition and biological effects of different herbs is still being done to identify biologically active natural compounds. 30,32 For example, V. heyneana is used in Traditional Vietnamese Medicine to treat arthritis, bronchitis, boils, inflammation, and menstrual irregularities. These biological effects in the stems of V. heyneana may result from the bioactive phytochemical compounds.…”

Section: Phytochemical Constituentsmentioning

confidence: 99%

Phytochemical Screening, Antioxidant and Xanthine Oxidase Inhibitory Activities of Vitis heyneana Schult. Stem Extracts From Vietnam

2023

TJNPR

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Generally, these agents have the ability to oxidize proteins, lipids, and nucleic acids and produce hazardous byproducts. These byproducts can cause cellular damage, such as changes in membrane structure, damage to organelles, damage to DNA, and dysfunction of cells, in addition to a number of serious illnesses (e.g., diabetes, hypertension, gouty inflammation, dyslipidemia, atherosclerosis, etc.). 4,[8][9][10] Previous reports have demonstrated that gout is associated with comorbidities such as hypertension, renal disease, diabetes mellitus, metabolic syndrome, hyperlipidemia and atherosclerosis, cancer, and aging. 2,11 Therefore, antioxidant therapy using bioactive compounds that inhibit XO activity is frequently suggested as an effective method to prevent gout complications and related ailments. Xanthine oxidase inhibitors (XOIs) e.g., allopurinol, topiroxostat, febuxostat, and pyranostat are a class of medications used for lowering uric acid level in the management of gout. 12,13 Allopurinol, introduced in 1966, is the most commonly used drug to lower urate levels in serum and urine. 14 It has been shown to be effective in reducing flares and tophi as urate levels decrease, reducing cardiovascular mortality, the risk of developing chronic kidney disease, the risk of prostate cancer, [15][16][17] as well as anti-inflammatory, and analgesic effects. 12 However, due to the long-term treatment, allopurinol may lead to many adverse effects including gastrointestinal bleeding, renal toxicity, 5,18 hypersensitivity syndrome and rashes, 13 toxic epidermal necrolysis syndrome, and liver function abnormalities. 5 Therefore, the search for new XO inhibitors, especially natural compounds, is still necessary. Studies have reported that bioactive compounds such as polyphenols (e.g., flavonoids, tannins, and coumarins), saponins, terpenoids, and alkaloids showed uric acid-lowering effects and were effective in inhibiting XO. 19,20 Furthermore, these compounds may also contribute to the improvement of gout by impeding oxidative stress. 20 The genus Vitis L. (belonging to the family Vitaceae) contains 81 accepted species, 21 and they are well known for their many uses in

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“…Indonesia, located in South-East Asia, boasts a remarkable biodiversity of medicinal plants and diverse ethnic groups [6,7]. Within the country, various traditional steam bath methods are employed for different medical purposes.…”

Section: Introductionmentioning

confidence: 99%

Ethnobotanical survey of herbal steam baths among the Tenggerese community in Bromo Tengger Semeru National Park, Indonesia

Bhagawan,

Ekasari,

Agil

2024

IOP Conf. Ser.: Earth Environ. Sci.

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The use of traditional medicines, including medicinal plant in steam baths, is widespread in various traditional healthcare systems. This study aims to document and evaluate the plant species used in herbal steam baths within the Tenggerese community in the Bromo Tengger Semeru National Park, Indonesia, with a focus on women’s reproductive health. A combination of semi-structured interviews and observations was conducted with 13 female informants, including traditional birth attendants and women with children. A total of 12 plant species from 9 families were identified, with Cananga odorata, Piper betle, Rosa chinensis, and Jasminum sambac being the most frequently mentioned. The preparation and utilization of herbal steam baths in the Tenggerese community, particularly in postpartum care, were described. Several plants commonly used in the steam baths have been studied for their phytochemical compounds and pharmacological properties, supporting their traditional use.

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Ethnomedicinal study, phytochemical characterization, and pharmacological confirmation of selected medicinal plant on the northern slope of Mount Wilis, East Java, Indonesia

Cited by 8 publications

References 37 publications

Kajian Literatur: Etnomedisin sebagai Analgesik di Indonesia

Kajian Literatur: Etnomedisin sebagai Analgesik di Indonesia

Phytochemical Screening, Antioxidant and Xanthine Oxidase Inhibitory Activities of Vitis heyneana Schult. Stem Extracts From Vietnam

Ethnobotanical survey of herbal steam baths among the Tenggerese community in Bromo Tengger Semeru National Park, Indonesia

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