Ethnomedicinal uses, phytochemistry, pharmacological activities and toxicological effects of Mimosa pudica- A review

Oluwapelumi, Adurosakin E.; Iweala, E. E. J.; Otike, Johnpaul O.; Dike, Emmanuel Dike; Uche, Miracle Ebubechi; Owanta, Julie I.; Ugbogu, Ositadinma Chinyere; Chinedu, Shalom Nwodo; Ugbogu, Eziuche Amadike

doi:10.1016/j.prmcm.2023.100241

Cited by 9 publications

(6 citation statements)

References 82 publications

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“…Due to the different bioactive compounds present within the plant, Mimosa pudica has a wide array of pharmacological activities. [44][45] These include antioxidant, antimicrobial, wound healing, anxiolytic, anthelmintic, hepatoprotective, antimalarial, anti-inflammatory, antidiabetic, and anticancer properties. Even though Mimosa pudica and its compounds are active against many diseases, including life-threatening diseases such as cancer 46 and diabetes 47 , no clinical trials or quality control studies are available in the literature to confirm this plant's safe and effective doses for disease prevention and treatment.…”

Section: Resultsmentioning

confidence: 99%

Traditional Healing Practices and Folk Medicines in Thailand: A Case Study of Huai Yot District, Trang Province

2024

TJNPR

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A traditional medical practitioner, also known as a traditional healer or folk healer, is acknowledged by their community for their skill in delivering health care using various procedures. 1,2 These methods include using plant, animal, and mineral materials. Their expertise is deeply rooted in the social, cultural, and religious contexts of the community, as well as in the prevalent understandings and attitudes toward health, mental well-being, and the origins of diseases and disabilities. [1][2][3] The World Health Organization (WHO) and other international organizations recognize the importance of traditional medicine and advocate for its integration into national healthcare systems. 2,[4][5][6] This recognition underscores its role in achieving global health goals, especially in areas lacking access to conventional medicine. It serves as a primary healthcare resource for millions, offering treatments that are accessible, affordable, and culturally familiar. [6][7][8][9] Beyond physical ailments, traditional medicine often addresses mental and spiritual well-being, reflecting a holistic approach to health. 3,7,8 Its impact extends to the pharmacological field, where many modern medicines originated in traditional remedies. [10][11][12] Integrating traditional and modern medicine can enrich healthcare systems, providing diverse treatment options and promoting patient autonomy.

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Section: Resultsmentioning

confidence: 99%

Traditional Healing Practices and Folk Medicines in Thailand: A Case Study of Huai Yot District, Trang Province

2024

TJNPR

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“…A succulent plant called A. vera is well-known for its therapeutic benefits and is frequently utilized in many different treatments 119 . Its leaves contain several beneficial secondary metabolites, including chrysophanol, aloin, and aloe-emodin.…”

Section: Phytochemical Constituents and Its Medicinal Propertiesmentioning

confidence: 99%

Venom Vanquish: A Comprehensive Review on Ethnobotany and Phytochemistry of Significant Traditional Medicinal Plants

T. Dhanya,

Kavinila,

David Paul Raj

2024

JNR

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Snakebite is a significant public health concern in many parts of the world, particularly in regions where venomous snakes are prevalent. Snakebites can range from mild to life-threatening, depending on the species of snake, the amount of venom injected, and the location of the bite. Globally, an estimated 5 million people are affected by snake bites each year, according to recent statistics. Since ancient times, traditional medicinal plants have been used to cure a wide range of illnesses, including snake bites. Secondary metabolites contained in plants were efficient in reducing the effects of snake venom. Snake venom is a potent toxin that can cause severe damage to the human body, affecting the nervous system, cardiovascular system, or both. Symptoms can range from mild swelling to life-threatening paralysis, respiratory failure, and hemorrhage. Enzyme activity is inhibited by flavonoids, alkaloids, and tannins, which additionally hinder blood from clotting and lessen inflammation. Treatments for snake bites that are more beneficial and less hazardous could result from the isolation and synthesis of natural drugs. With the use of cutting-edge scientific methods, we can maximize their potential and use their secondary metabolites to develop novel medications and therapies. The study of these plants and their potential uses in contemporary medicine requires more funding and investigation. This will advance our knowledge of these plants and help us create cures for some of the most lethal diseases.

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“…[1][2][3] The whole MP plant is used in healthcare having a broad spectrum of activities. [1,2] The leaves of MP have shown various biological properties including antiinflammatory, antioxidant, antinociceptive, wound healing, hypolipidemic, diuretic, antidiabetic, anticonvulsant, antidepressant, antimicrobial, anti-anxiety, anti-depression, memory enhancer, antifungal, and antidiarrheal activity. [1][2][3] There are various qualitative studies of MP leaves in different extracts, where the presences of flavonoids, alkaloids, terpenoids, carbohydrates, saponins, amino acids, phenols, tannins, proteins and steroids, while glycosides, fats, oils, resins, reducing sugars, phytosterols and phlobatannins were found to be absent.…”

Section: Introductionmentioning

confidence: 99%

“…This plant is observed over the whole globe (Muhammad et al., 2016). Due to their potential benefits, it has remained in use since ancient systems of medicine, including Ayurveda, Unani, Chinese, and Greco‐Arab (Unani‐Tibb) [1–3] . The whole MP plant is used in healthcare having a broad spectrum of activities [1,2] .…”

Section: Introductionmentioning

confidence: 99%

“…Due to their potential benefits, it has remained in use since ancient systems of medicine, including Ayurveda, Unani, Chinese, and Greco‐Arab (Unani‐Tibb) [1–3] . The whole MP plant is used in healthcare having a broad spectrum of activities [1,2] . The leaves of MP have shown various biological properties including anti‐inflammatory, antioxidant, antinociceptive, wound healing, hypolipidemic, diuretic, antidiabetic, anticonvulsant, antidepressant, antimicrobial, anti‐anxiety, anti‐depression, memory enhancer, antifungal, and antidiarrheal activity [1–3] .…”

Section: Introductionmentioning

confidence: 99%

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Quantification of Phytochemicals and Metal Ions as well as the Determination of Volatile Compounds, Antioxidant, Antimicrobial and Antacid Activities of the Mimosa pudica L. Leaf: Exploration of Neglected and Under‐Utilized Part

Gandhi,

Prasad,

Kumar

et al. 2023

Chemistry & Biodiversity

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Mimosa pudica L. (MP) is well‐known plant in traditional medicinal system, especially in India. Unfortunately, leaves of MP are less explored. To determine the food and nutritional value of the neglected part of Mimosa pudica L. (MP), that is MP leaves, phytochemicals and metal ions of MP were quantified by newly developed HPLC and ICPOES‐based methods. The content of phytochemicals observed using HPLC analysis for chlorogenic acid, catechin, and epicatechin was 141.823 (±8.171), 666.621 (±11.432), and 293.175 (±12.743) μg/g, respectively. Using GC/MS/MS analysis, fatty acid like oleic acid were identified. In ICP‐OES analysis, a significant content of Na, K, Ca, Cu, Fe, Mg, Mn, and Zn was observed. The observed TPC and TFC for MP leaf extracts was 44.327 (±1.041) mg GAE/ g of wt. and 214.217 (±4.372) mg QCE/ g of wt., respectively. The DPPH assay depicted a strong antioxidant activity of MP leaf extracts with IC50 values of 0.796 (±0.081) mg/mL and a TEAC value of 0.0356 (±0.0003). A significant antacid activity (666 mg MP+400 mg CaCO3 >400 mg CaCO3 ≫666 mg Gelusil) of MP leaves was noticed. The methanolic extract of MP leaves demonstrated anti‐microbial activity against Staphylococcus aureus (15±2mm), Pseudomonas aeruginosa (12±2mm) and Escherichia coli (10±2mm). In silico studies confirmed the in vitro results obtained for antioxidant, antiacid, and anti‐microbial activities. In addition, in silico studies revealed the anti‐cancerous and anti‐inflammatory potential of the MP leaves. In summary, this study demonstrated the medicinal significance of MP leaves and the conversion of agro‐waste or the under‐utilized part of MP into pharmaceutical potent materials. Consequently, the present study highlighted that MP leaves alone have medicinal importance with good nutritional utility and possess large promise in the pharma industry along with improving bio‐valorization and the environment.

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Ethnomedicinal uses, phytochemistry, pharmacological activities and toxicological effects of Mimosa pudica- A review

Cited by 9 publications

References 82 publications

Traditional Healing Practices and Folk Medicines in Thailand: A Case Study of Huai Yot District, Trang Province

Traditional Healing Practices and Folk Medicines in Thailand: A Case Study of Huai Yot District, Trang Province

Venom Vanquish: A Comprehensive Review on Ethnobotany and Phytochemistry of Significant Traditional Medicinal Plants

Quantification of Phytochemicals and Metal Ions as well as the Determination of Volatile Compounds, Antioxidant, Antimicrobial and Antacid Activities of the Mimosa pudica L. Leaf: Exploration of Neglected and Under‐Utilized Part

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