Etiology, clinical characteristics, and outcomes of acute pancreatitis in patients at Assiut University Hospital

Alkareemy, Enas Ahmed Reda; Ahmed, Lobna Abdel-Wahid; El‐Masry, Muhammad Abbas; Habib, Hany; Mustafa, Mohamed H.

doi:10.1186/s43162-020-00025-w

Cited by 14 publications

(19 citation statements)

References 13 publications

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“…In this study, the incidence of gall stones was 71.1% whereas the incidence of alcohol induced pancreatitis was 26.6 % which is similar to Kashid et al [6], where the incidence of gall stones was found to be 36.4 % and that of alcohol 29.1 %,In the study done by Buchler MW et al [15], incidence of gall stones as 45 %. Other studies by Pezelli et al [13], Zarnescu et al [14] , Alkareemy EA et al [16] also shows that the incidence is more in biliary pathology.…”

Section: Discussionmentioning

confidence: 80%

Clinical Profile of Acute Pancreatitis

Yadav

Raya

Kumar

et al. 2022

Janaki Med. Coll. J. Med. Sci.

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Background and objectives: Acute pancreatitis is a disorder that has a wide-ranging presentation, etiology, multifactorial pathogenesisandclinicalconsequencesfrommildselflimitingtoseverelife threatening. The aim of this study is to evaluate demographic characteristics, etiology, clinical presentation and its management. Materials and methods: This retrospective study was carried out in Department of Surgery of National Medical College and Teaching Hospital. A total of45 patients with diagnosis as acute pancreatitis over period of March 2020 to February 2022 were included in this study. History and detailed clinical examination was performed as per the working proforma which included. Chi square test were used for correlation analysis. Data analysis was done using SPSS (Statistical Package for social sciences), version 25. Results: Most of acute pancreatitis were seen in 20-39 years of age group with mean age of 39.7 years. 66.6% patients were female. Gall stone was the most common cause (71.1% patients) of pancreatitis. Abdominal pain was the most common mode of presentation, and tenderness the most common sign. Most of the patients were managed conservatively. Median hospital stay was 9 days. Conclusion: Acute pancreatitis is a common cause of acute abdomen in patients presenting to the emergency department. Gall stone is the most common cause of acute pancreatitis .Clinical diagnosis along with biochemical and radiological findings are required for diagnosis .The management is mainly conservative.

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Section: Discussionmentioning

confidence: 80%

Clinical Profile of Acute Pancreatitis

Yadav

Raya

Kumar

et al. 2022

Janaki Med. Coll. J. Med. Sci.

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“…The only notable finding was the history of blunt abdominal trauma a day prior to the presentation of symptoms which was acquired through a thorough and detailed history. It is important to note that gallstones and alcohol abuse account for 70% of cases of acute pancreatitis [ 1 ]. Hypertriglyceridemia accounts for 2-5% and a large percentage of cases fall under the umbrella term idiopathic.…”

Section: Discussionmentioning

confidence: 99%

“…The pathogenesis resulting in pancreatic injury has multiple etiologies with gallstones and alcohol consumption contributing to a large majority of cases. Consequently, one uncommon cause of acute pancreatitis, direct abdominal trauma, often gets overlooked [ 1 ]. This case describes a 20-year-old male presenting to the hospital with isolated pancreatic tail injury after multiple blows to his abdomen.…”

Section: Introductionmentioning

confidence: 99%

An Unusual Case of Isolated Pancreatitis Secondary to Blunt Abdominal Trauma

Hamzoian¹,

Plasencia²,

Ekpa³

et al. 2022

Cureus

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Acute pancreatitis is an inflammatory condition affecting a large population and resulting in one of the most common causes of gastrointestinal hospitalizations in the United States. The pathogenesis resulting in pancreatic injury has multiple etiologies with gallstones and alcohol consumption contributing to a large majority of cases. Consequently, one uncommon cause of acute pancreatitis, direct abdominal trauma, often gets overlooked. This case describes a 20-year-old male with no past medical history or surgical interventions presenting to the hospital with two days worth of abdominal pain. Physical exam was negative for erythema, ecchymosis and lacerations but further questioning revealed a recent history of an altercation resulting in multiple blunt blows to the abdomen. CT abdomen with contrast was positive for an edematous appearing pancreatic tail with surrounding soft tissue stranding; no pancreatic fluid collections, normal gallbladder and no intrahepatic or extrahepatic biliary ductal dilation. Pancreatitis has a multitude of etiologies and practitioners should address the insulting event as well as the pathological sequelae to prevent reoccurrence of the condition. The importance of taking a full and thorough history should not be overlooked; this could lead to misdiagnosis and misjudgment of the underlying pathological process. We propose the notion that there is a significant number of patients diagnosed with idiopathic pancreatitis who may have more accurately been diagnosed with traumatic pancreatitis with a more thorough history. Additionally, due to the pancreas’s retroperitoneal location, isolated injury with abdominal trauma, such as in this patient, is quite rare. It is critical to differentiate the underlying cause of acute pancreatitis to further counsel patients about avoidance of precipitating factors. We would like to stress the importance of obtaining a thorough history and ruling out alternative causes of patient presentation as management differs greatly after treatment of the acute phase reaction. In patients with traumatic pancreatitis, physicians should establish that there were no residual abdominal injuries and advise patients to restrain from any activities that would result in any sequential abdominal trauma.

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“…For example, the US has idiopathic acute pancreatitis at the top of the list, whilst in Latin America, acute biliary pancreatitis was the most frequent (11) . According to Alkareemy et al (12) , the most common etiology (56%) of acute pancreatitis patients were secondary to gall bladder stones, 26% were idiopathic, and 12% were ERCP. Idiopathic pancreatitis may be due to occult gall stones, dysfunction of the sphincter of Oddi, or cystic fibrosis in children or young adults (13) .…”

Section: Discussionmentioning

confidence: 99%

Association of Systemic Inflammatory Response syndrome with Serum Creatinine, Albumin, and C-Reactive Protein in Acute Pancreatitis Patients

Nageb

Haredi²,

El‐Masry³

et al. 2022

The Egyptian Journal of Hospital Medicine

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Background and aim: Acute pancreatitis (AP) is one of the leading causes of hospital admission from gastrointestinal diseases, with approximately 300,000 emergency department visits each year. Outcomes from acute pancreatitis are influenced by risk stratification, fluid and nutritional management, follow-up care, and risk-reduction strategies. Objective: The current work aimed to assess the pattern and outcome of acute pancreatitis. Patients and methods: A total of 70 patients with acute pancreatitis were enrolled. Those patients were subjected to history and clinical evaluation. All baseline laboratory and radiological data were recorded. Results: Serum albumin was negatively correlated with the length of hospitalization. Severe inflammatory response syndrome was associated with higher C-reactive protein and serum albumin level, in the Contrast-enhanced CT (CECT) scan and systemic inflammatory response syndrome (SIRS) in the first 48 hours were significantly associated with severe inflammation and necrosis. Conclusion: Acute pancreatitis is a challenging condition, which vary in severity and duration. Early diagnosis and severity classification have substantial impact on proper care. A more complicated disease is associated with the early onset of systemic inflammatory response syndrome.

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Etiology, clinical characteristics, and outcomes of acute pancreatitis in patients at Assiut University Hospital

Cited by 14 publications

References 13 publications

Clinical Profile of Acute Pancreatitis

Clinical Profile of Acute Pancreatitis

An Unusual Case of Isolated Pancreatitis Secondary to Blunt Abdominal Trauma

Association of Systemic Inflammatory Response syndrome with Serum Creatinine, Albumin, and C-Reactive Protein in Acute Pancreatitis Patients

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