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For many years the value of various operations on patients with chronic hyperplastic sinus disease for the relief of asthma has been a greatly debated problem. There has been and remains a marked difference of opinion between the proponents of the conservative treatment of asthma and those of the radical type of surgical intervention. It is planned to report here the effect of the pansinus operation on thirteen patients with markedly advanced chronic hyperplastic pansinusitis associated with asthma. In every case the operation consisted of a bilateral fronto-ethmosphenoidectomy and the Caldwell-Luc operation. This extensive surgical procedure was not done on account of the asthma but was performed primarily for the relief of symptoms of the sinus disease\p=m-\thatis, severe headache, marked nasal discharge or toxemia\p=m-\ and to lessen the probability of the development of complications, such as meningitis or abscess of the brain. ETIOLOGIC RELATIONSHIP OF SINUS DISEASE TO ASTHMAUntil recent years chronic sinus disease has been generally regarded as a frequent cause of asthma. As a result the sinuses have been attacked by all the various types of operation, both conservative and radical, with the hope of curing the asthma. With this in mind some writers 1 have reported marvelous success in the relief of asthma by means of operation on the sinuses.
For many years the value of various operations on patients with chronic hyperplastic sinus disease for the relief of asthma has been a greatly debated problem. There has been and remains a marked difference of opinion between the proponents of the conservative treatment of asthma and those of the radical type of surgical intervention. It is planned to report here the effect of the pansinus operation on thirteen patients with markedly advanced chronic hyperplastic pansinusitis associated with asthma. In every case the operation consisted of a bilateral fronto-ethmosphenoidectomy and the Caldwell-Luc operation. This extensive surgical procedure was not done on account of the asthma but was performed primarily for the relief of symptoms of the sinus disease\p=m-\thatis, severe headache, marked nasal discharge or toxemia\p=m-\ and to lessen the probability of the development of complications, such as meningitis or abscess of the brain. ETIOLOGIC RELATIONSHIP OF SINUS DISEASE TO ASTHMAUntil recent years chronic sinus disease has been generally regarded as a frequent cause of asthma. As a result the sinuses have been attacked by all the various types of operation, both conservative and radical, with the hope of curing the asthma. With this in mind some writers 1 have reported marvelous success in the relief of asthma by means of operation on the sinuses.
CHRONIC disease of the accessory nasal sinuses is thought by many to be a very important factor in the production of chronic bronchitis and bronchitic asthma. One of the commonest problems that confront us in the treatment of these two diseases is a decision as to the advisability of treating the accessory nasal sinuses surgically. In the majority of cases the chronic " disease " of these sinuses is recognised clinically by a thickening of their lining or mucoperiosteum, and the presence of some mucus in the sinus cavity. When one sinus, such as the antrum, shows thickening of its lining, quite often other sinuses (sphenoids, ethmoids or frontals) may also show this abnormality. Usually the antra show the greatest thickening over a larger area and are often singled out for surgical intervention. The work reported here is an attempt to evaluate the effect of radical antral surgery (including removal of this thickened mucoperiosteum, and the establishment of free drainage) on the bronchitic asthma or chronic bronchitis present. This work was thought advisable because of the conflicting opinions found in the literature on the subject. Published results range from the optimistic reports of Potts 1 or Smith 2 to reports of little or no beneficial effect by Rackemann 3 and Piness. 4 We thought that one cause of this diversity of opinion was that sufficient time was not allowed to elapse after the operation before the result was finally recorded. In 1929, therefore, we decided to study a number of patients suffering from bronchitic asthma and chronic bronchitis and to observe them carefully over a long period of time. Thirty-one asthmatic patients were selected for operation.
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