Etiology of Catheter-Associated Sepsis

Surgical Treatment of Septic Jugular Thrombophlebitis in Nine Horses

“…Various materials have been used for catheter production including in likely order of decreasing thrombogenicity: polypropylene, polyethylene, PTFE, silicone rubber, polyvinylchloride, and polyurethane 11 . Material used can also have an effect on bacterial colonization with several studies reporting increased bacterial colonization rate in materials associated with higher rates of thrombus formation 12 …”

Role of Arterial catheters as a source of Hospital related Bacteremia

“…Catheters that irritate the vascular intima and provide thrombogenesis and the catheters that are made of materials that are intrinsically thrombogenic are likely to be associated with an increased risk for device associated infection [56].Older studies suggest that stiff catheters were associated with higher infection rates. Such catheters are thought to be more mobile in the insertion tract and thought to be more thrombogenic [57].A clear association has been established between the thrombogenecity of a catheter and the risk for device associated infection [58].…”

Guidelines for the Prevention of Intravascular Catheter-related Infections: Recommendations Relevant to Interventional Radiology for Venous Catheter Placement and Maintenance

“…On the other hand, biofilm formation by C. albicans occurs more readily on silicone elastomer catheter surfaces than on polyurethane catheters (26). Modification of the biomaterial surface properties has been shown to influence the ability of C. albicans to form biofilm (27). Some catheter materials have surface irregularities that enhance the microbial adherence of certain species (e.g., S. epidermidis and C. albicans) (26, 27).…”

“…Modification of the biomaterial surface properties has been shown to influence the ability of C. albicans to form biofilm (27). Some catheter materials have surface irregularities that enhance the microbial adherence of certain species (e.g., S. epidermidis and C. albicans) (26, 27). Catheters made of these materials are particularly vulnerable to microbial colonization and subsequent infection.…”