Abstract. The Grou River is one of the main rivers that feed the reservoir of the Sidi Mohammed Ben Abdellah (SMBA) dam in Morocco. However, this river is particularly threatened by the pollution problem. It is in this context that this study aims to study the effect of wastewater from the rural commune of Jmaa Moulblad on the physicochemical quality of the waters of this river. We analyzed 11 physicochemical parameters (T° of area, T° of water, pH, EC, mV, Sal, TDS, BOD, COD, SS and TOC), with a monthly frequency since the month of December 2014 until November 2015. The results obtained show a worrying situation of the state of this watercourse. To remedy this problem, we recommend pre-treatment of wastewater before discharge and the implementation of a management plan and sustainable management of the Grou River watershed.