Eudesmane-type sesquiterpenoids: Structural diversity and biological activity

Wu, Guang-Xu; Zhao, Hao-Yu; Peng, Cheng; Liu, Fei; Xiong, Liang

doi:10.1016/j.heliyon.2024.e35270

Heliyon

2024

DOI: 10.1016/j.heliyon.2024.e35270

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Eudesmane-type sesquiterpenoids: Structural diversity and biological activity

Guang-Xu Wu,

Hao-Yu Zhao,

Cheng Peng

et al.

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Research Progress on Sesquiterpenes from the Genus Ainsliaea

Zhang,

Sun,

Liu

et al. 2024

Molecules

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Sesquiterpenes constitute the principal components of the genus Ainsliaea, encompassing guaiane, germacrane, eudesmane, and polymer sesquiterpene lactones types. These secondary metabolites exhibit diverse pharmacological activities, including antitumor, antibacterial, anti-inflammatory, antiviral, antioxidant, hepatoprotective, and neuroprotective effects. Through a comprehensive literature search of the Web of Science, PubMed, SciFinder, and CNKI databases, it was discovered that there are as many as 145 main sesquiterpenoids in the genus Ainsliaea. However, the nuclear magnetic resonance (NMR) data for the sesquiterpenes in this genus have not been systematically compiled and summarized. Therefore, this review aims to highlight the chemical structures, NMR data, and pharmacological activities of sesquiterpenes in Ainsliaea. By meticulously analyzing published scholarly literature, our goal is to provide a solid foundation for further exploration of new sesquiterpenes and extensive utilization of this genus.

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Research Progress on Sesquiterpenes from the Genus Ainsliaea

Zhang,

Sun,

Liu

et al. 2024

Molecules

View full text Add to dashboard Cite

show abstract

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Eudesmane-type sesquiterpenoids: Structural diversity and biological activity

Cited by 1 publication

References 128 publications

Research Progress on Sesquiterpenes from the Genus Ainsliaea

Research Progress on Sesquiterpenes from the Genus Ainsliaea

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