European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009–2014

Dittmar, Daan; Uter, Wolfgang; Bauer, Andrea; Fortina, A Belloni; Bircher, Andreas J.; Czarnecka‐Operacz, Magdalena; Dugonik, Aleksandra; Elsner, Peter; Gallo, Rosella; Ghaffar, S.A.; Giménez-Arnau, A.M.; Johnston, Graham A.R.; Krêcisz, Beata; Filon, Francesca Larese; Rustemeyer, Thomas; Sadowska‐Przytocka, Anna; Sánchez‐Pérez, Javier; Schnuch, Axel; Simon, Dagmar; Śpiewak, Radosław; Spring, Philipp; Corradin, Maria Teresa; Valiukevičienė, Skaidra; Vok, Marko; Weißhaar, Elke; Wilkinson, S. M.; Schuttelaar, Marie L A; Aberer, Werner; Ballmer‐Weber, Barbara; Grabbe, Jürgen; Beiteke, Ulrike; Brasch, Jochen; Fuchs, Thomas; John, Swen Malte; Mahler, Vera; Pesonen, Maria; Jolanki, Riitta; Rantanen, Tapio; Armario‐Hita, J.C.; Fernández‐Redondo, Virginia; García‐Gavín, J.; Mercader, Patricia; Ruiz, Inmaculada Fortes; Silvestre, J.F.; Balato, Anna; Ayala, Fabio; Peserico, Andrea; Sliuziaviciene, Gondinga; Kieć-Swierczyńska, M; Kmecl, Tanja; Pandurovic, Maja Kalac; Kecelj, Nada; Lunder, Tomaž; Godnič, Mojca Simončič; Chowdhury, Mahbub M. U.; Cooper, Susan M.; English, John; Cousen, P.; Horne, Helen; Gawkrodger, David J.; Sabroe, R.A.; Green, Cathy M.; King, Charlotte; Ormerod, Anthony; Samson, Jane E.; Statham, B. N.; Stone, Natalie; White, Ian R.

doi:10.1111/cod.12966

Cited by 25 publications

(34 citation statements)

References 53 publications

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“…In particular, the percentage of males with contact dermatitis, was found to be between 11.8% and 40.8% with a median of 28.75%, while our results showed a male population of 31.29%. 15 Further on, OD manifested a minimum of 5.3% and a maximum of 47.6% in the European cohort study, while in our study we have found that 31.55% were diagnosed with OD. 15 At the same time, AD, HD, LD and FD manifested a minimum of 10.6%, 8.7%, 1.8% and 0.9% respectively, a maximum of 38.5%, 64.2%, 22.4% and 32.9% respectively and finally a median of 24.9%, 25.75%, 4.55% and 11.75% respectively.…”

Section: Discussioncontrasting

confidence: 45%

An epidemiological study of allergic contact dermatitis in Greece: prevalence of sensitization to an adapted European baseline series’ allergens

et al. 2018

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Background: Contact dermatitis is a common skin disorder related to environmental exposures affecting, all age groups, and both genders. The pattern of contact sensitization to a series of allergens included in the European baseline series has already been studied for a number of EU countries by the ESSCA Network. The current study aims to explore the patterns of contact dermatitis in Greece through a patch test against a large number of allergens provoking contact dermatitis.Methods: Retrospective analyses of routine data of 668 patients were collected during 2014 in the Laboratory of Patch Testing, National Referral Centre of Occupational Dermatoses. Sensitization in all cases was tested with a battery of 28 allergens of the European baseline series and additional ones aiming to identify new sensitizations to inform the National baseline of allergens; information for an extended MOAHLFA index was also collected.Results: One at least positive result was found in 61.5% of the patients while 19.1% of those found to be sensitized in two or more allergens. Nickel sulphate, fragrance mix and balsam of Peru were the most prevalent allergens in the total population, as well as with respect to gender. Nickel is the most frequent allergen of baseline series, a result which is in agreement with other reports.Conclusions: Allergic contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease. Further studies should be directed towards that end, in order to facilitate more effective health policies.

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Section: Discussioncontrasting

confidence: 45%

An epidemiological study of allergic contact dermatitis in Greece: prevalence of sensitization to an adapted European baseline series’ allergens

et al. 2018

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“…Figure shows a study flow chart. Overall, 86 416 patients had been tested with the baseline series in 2009 to 2014; 44 300 of these were documented by the use of winalldat software, and were thus utilizable for the present analysis. We considered only the most recent consultation if one patient had multiple consultations.…”

Section: Resultsmentioning

confidence: 99%

European Surveillance System on Contact Allergies (ESSCA): Contact allergies in relation to body sites in patients with allergic contact dermatitis

et al. 2019

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Background Analyses of the European Surveillance System on Contact Allergies (ESSCA) database have focused primarily on the prevalence of contact allergies to the European baseline series, both overall and in subgroups of patients. However, affected body sites have hitherto not been addressed. Objective To determine the prevalence of contact allergies for distinct body sites in patients with allergic contact dermatitis (ACD). Methods Analysis of data collected by the ESSCA ( www.essca‐dc.org ) in consecutively patch tested patients, from 2009 to 2014, in eight European countries was performed. Cases were selected on the basis of the presence of minimally one positive patch test reaction to the baseline series, and a final diagnosis of ACD attributed to only one body site. Results Six thousand two hundred and fifty‐five cases were analysed. The head and hand were the most common single sites that ACD was attributed to. Differences between countries were seen for several body sites. Nickel, fragrance mix I, cobalt and methylchloroisothiazolinone/methylisothiazolinone were the most frequent allergens reported for various body sites. Conclusions Distinct allergen patterns per body site were observed. However, contact allergies were probably not always relevant for the dermatitis that patients presented with. The possibility of linking positive patch test reactions to relevance, along with affected body sites, should be a useful addition to patch test documentation systems.

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“…Another factor associated with MCAs was occupationally related dermatitis (OR 1.94), which had a similar strength as the factor active working adult age group (25‐59 years; OR 1.81). An explanation is the higher probability of allergen exposure through work (which may be undertaken in occlusive conditions and with pre‐existing skin irritation); this promotes sensitization …”

Section: Discussionmentioning

confidence: 99%

“…According to our observation, MCA patients usually present with widespread, long‐lasting and hard‐to‐treat eczema. The incidence of MCA patients varies among populations . Previous studies showed a higher prevalence of MCAs than expected in both general and dermatitis populations .…”

Section: Introductionmentioning

confidence: 90%

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Factors associated with multiple contact allergies in Thai dermatitis patients: A 10‐year retrospective study

Winayanuwattikun

Boonchai

2019

Contact Dermatitis

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Background Multiple contact allergies (MCAs) are defined as three or more positive patch test reactions to unrelated antigens. Factors associated with MCAs include female sex, older age, and certain eczema sites. Objectives To investigate the prevalence of MCAs, risk factors for their development, and patterns of allergen combinations. Methods This retrospective, case‐control study was conducted on patients suspected of having allergic contact dermatitis who had been patch tested with a baseline series in the period January 2007 to December 2016. Results Of the 2178 included patients, 531 (24.4%) had MCAs. A multivariate analysis showed that a generalized distribution of dermatitis represented the highest risk factor (odds ratio [OR] 3.97), followed by a history of metal allergy (OR 3.18). The other significantly associated factors were, in order of decreasing frequency, the dermatitis sites (hands/feet, extremities, and face), age ≥25 years, and occupationally related dermatitis; their ORs were <3. Conclusions The factors that were significantly associated with MCAs were identified. The ranking of the common contact allergens among MCA patients was comparable with that of non‐MCA patients. Metal and fragrance allergens were frequently found to cause concurrent positive reactions in MCA patients.

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European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009–2014

Abstract: The varying prevalences of polysensitization across Europe most likely reflect differences in patient characteristics and referral patterns between departments. Known risk factors for polysensitization are confirmed in a European dermatitis population.

Cited by 25 publications

References 53 publications

An epidemiological study of allergic contact dermatitis in Greece: prevalence of sensitization to an adapted European baseline series’ allergens

An epidemiological study of allergic contact dermatitis in Greece: prevalence of sensitization to an adapted European baseline series’ allergens

European Surveillance System on Contact Allergies (ESSCA): Contact allergies in relation to body sites in patients with allergic contact dermatitis

Factors associated with multiple contact allergies in Thai dermatitis patients: A 10‐year retrospective study

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